Figure 132.1
Epidermis of a freckle showing a hyperpigmented basal cell layer without elongated rete ridges or melanocytic hyperplasia. Magnification 20× (H&E). (...
Figure 132.5
(a) Simple lentigo. (b) Dermoscopic image of simple lentigo.
Figure 132.9
(a) Ink‐spot lentigo. (b) Dermoscopic image of an ink‐spot lentigo showing a bizarre‐looking black pigment network which is typical. (Courtesy of Dr ...
Figure 132.13
(a) Labial melanotic macule. (b) Dermoscopic image of a labial melanotic macule reveals a combination of grey‐brown dots arranged in parallel lines an...
Figure 132.17
Naevus of Ito, showing a typical distribution over the shoulder area.
Figure 132.21
Aquired dermal naevus. (a) Nested pattern of development in the upper portion of the lesion. There is no junctional component. Magnification 10× (H&E)...
Figure 132.25
(a) Overview (3.5 × 5 mm) of a junctional lentiginous naevus by reflectance confocal microscopy showing a ringed pattern. (b) Detail (1.2 × 1.7 mm) wh...
Figure 132.29
Compound conjunctival naevus. (a) Naevic aggregates are observed mainly beneath the conjunctival epithelium, in the substantia propria and partially a...
Figure 132.33
Recurrent naevus. (a) Macule developing within the scar of a previously excised melanocytic naevus. (b) Dermoscopic image showing a slightly asymmetri...
Figure 132.37
(a) Cockade naevus. (b) Dermoscropic image of a cockade naevus showing a darker, central homogeneous pattern, a lighter inner ring and a peripheral br...
Figure 132.41
Classic Spitz naevus. (a) A well‐circumscribed pink nodule. (b) A round, symmetrical lesion with dotted vessels and lack of pigmentation. (Courtesy o...
Figure 132.45
Common blue naevus. (a) Poorly circumscribed area of elongated, pigmented melanocytes in the dermis. The dendritic melanocytes are located between the...
Figure 132.49
Malignant blue naevus that has arisen in a previous cellular blue naevus. This lesion subsequently metastasized to the lymph nodes.
Figure 132.53
(a) Dysplastic nevus (4.2 × 6 mm) by reflectance confocal microscopy showing a more disarranged pattern with elongated junctional nests in the centre ...
Figure 132.2
(a) Freckles. (b) Dermoscopic image showing hyperpigmented lesions with reticular pattern and moth‐eaten edges.
Figure 132.6
(a) Solar lentigo in the middle of the left cheek. (b) Dermoscopic image of solar lentigo showing a uniform structureless macule with sharply demarcat...
Figure 132.10
Mucosal melanosis. (a) Squamous epithelium of the oral cavity with hyperpigmentation of the basal cells. Magnification 10× (H&E). (b) Hyperpigmentatio...
Figure 132.14
Mongolian spot in the lumbosacral area. (Courtesy of Professor A. Katsarou‐Katsari, Pediatric Dermatology Unit, Andreas Sygros Hospital, Athens, Gree...
Figure 132.18
Speckled lentiginous naevi: numerous darker macules and papules (representing junctional and compound naevi) can be seen on a faintly visible tan macu...
Figure 132.22
(a) Junctional naevus. (b) Dermoscopic image of a junctional naevus showing a reticular pattern with a smooth ending at the periphery.
Figure 132.26
(a) Overview (1.8 × 2.6 mm) of a compound naevus by reflectance confocal microscopy. Some nests filling the papillae are clearly visible in the centre...
Figure 132.30
Conjunctival naevus. (a) A well‐circumscribed papule of various shades of brown. (b) Dermoscopic image showing homogeneous brown‐greyish pigmentation ...
Figure 132.34
Halo naevus. (a) Dense lymphocytic infiltrate with disruption of the naevomelanocytic aggregates, especially in the mid and deep portion of the dermal...
Figure 132.38
Targetoid haemosiderotic naevus. (a) Naevus acutely presenting with a haemorrhagic halo. (b) Dermoscopic image showing a peripheral, structureless, pu...
Figure 132.42
(a) Pigmented Spitz naevus. (b) Dermoscopic image of a pigmented Spitz naevus showing a well‐circumscribed symmetrical nodule with a papillomatous sur...
Figure 132.46
Cellular blue naevus. (a) Multiple amelanotic nodules of naevomelanocytes are characteristic. The cellular component of blue naevus extends deep to th...
Figure 132.50
Dysplastic naevus syndrome: multiple clinically atypical naevi on the back. The lower surgical scar on the sacral area corresponds to a previously rem...
Figure 132.3
Lentigo simplex: hyperpigmentation is evident in the basal and squamous epidermal cells. There is a slight increase of non‐atypical melanocytes betwee...
Figure 132.7
PUVA‐induced lentigines in a patient with psoriasis.
Figure 132.11
Penile lentiginosis: prominent melanocytic dendrites among the hyperpigmented basal layer cells. Magnification 40× (H&E). (Courtesy of Dr K. Frangia,...
Figure 132.15
Naevus of Ota.
Figure 132.19
Junctional naevus. (a) Aggregates of naevomelanocytic cells in the rete ridges of a hyperplastic epidermis. There is no dermal component. Magnificatio...
Figure 132.23
Compound naevus. (a) Hyperpigmented papule surrounded by symmetrical, lighter brown, macular area. (b) Dermoscopic image showing a structureless brown...
Figure 132.27
Compound acral naevus. (a) The junctional component predominates, with variable sized and shaped nests located mainly to the tips of the rete ridges. ...
Figure 132.31
Nail matrix naevus. (a) A longitudinal pigmented band. (b) Dermoscopic image showing brown, longitudinal parallel lines with regular spacing and thick...
Figure 132.35
(a) Halo naevus. (b) Dermoscopic image of a halo naevus showing a symmetrical compound naevus (globular pattern) surrounded by a whitish halo.
Figure 132.39
Compound naevus of Spitz. (a) Sparsly demarcated naevomelanocytic proliferation at the junctional area and mainly in the dermis. The dermal component ...
Figure 132.43
Atypical Spitz tumour. (a) Asymmetrical nodule with heterogeneous pigmentation. (b) Dermoscopic image of the symmetrical, peripheral distribution of p...
Figure 132.47
(a) Blue naevus. (b) Dermoscopic image of a blue naevus showing a homogeneous blue pattern.
Figure 132.51
Compound dysplastic naevus. (a) Hyperplastic epidermis with bridging of the adjacent rete ridges. Nests of melanocytes, of variable sizes and shapes, ...
Figure 132.4
(a, b) Multiple lentigines in a patient with the Carney complex and a PRKAR1A mutation. Only about a third of patients with the complex have this clas...
Figure 132.8
Ink‐spot lentigo. (a) Epidermis with lentiginous hyperplasia and intensely hyperpigmented basal cells. Foci of less or no pigmentation are usually obs...
Figure 132.12
Genital melanosis.
Figure 132.16
Naevus of Ota. (a) Skin with sparse dendritic melanocytes in the upper dermis and no melanocytic hyperplasia in the overlying epidermis. Magnification...
Figure 132.20
Acquired compound naevus. (a) Naevomelanocytic proliferation in the junctional area and the dermis. The dermal component extends beyond the boundaries...
Figure 132.24
(a) Dermal naevi. (b) Dermoscopic image showing a symmetrical, flesh‐coloured, homogeneous pattern with coma‐shaped vessels.
Figure 132.28
(a) Naevus on the sole of a foot. (b) Dermoscopic image of acral naevus showing a parallel furrow pattern.
Figure 132.32
(a) Combined naevus. (b) Combined naevus with eccentric, structureless, bluish area and peripheral, brown, globular pattern. (Courtesy of Dr D. Sgour...
Figure 132.36
Meyerson naevus. (a) A small‐sized naevus with an eczematous component. (b) Dermoscopic image showing yellowish crusts covering a naevus with a faint ...
Figure 132.40
Pigmented spindle cell naevus of Reed. (a) An almost exclusively intraepidermal naevomelanocytic lesion with heavily pigmented spindle cells arranged ...
Figure 132.44
Reed naevus. (a) Darkly pigmented symmetrical macule. (b) Dermoscopic image showing a ‘starburst’ pattern with diffuse blue‐black pigmentation and sym...
Figure 132.48
(a) Cellular blue naevus. (b) Dermoscopic image of a cellular blue naevus showing a well‐circumscribed, protuberant nodule with homogeneous dark blue ...
Figure 132.52
(a–e) Clinically atypical naevi of variable shapes, sizes and pigmentary patterns (on the left) and their corresponding dermoscopic images (on the rig...
