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Figure c142/f001
Figure 142.1
Pathological features of actinic keratoses showing alternating parakeratosis and hyperkeratosis.
Figure c142/f005
Figure 142.5
Dermoscopy showing thickened warty appearance of seborrhoeic keratosis.
Figure c142/f009
Figure 142.9
Solitary basal cell carcinoma with pearly edge and minimal hyperkeratosis.
Figure c142/f013
Figure 142.13
Actinic keratosis (AK) management algorithm. *Treatment should be decided following discussion with the patient, assessment of treatment availability ...
Figure c142/f017
Figure 142.17
Cutaneous horn with low height‐to‐base ratio. Pathology showed squamous cell carcinoma at the base.
Figure c142/f021
Figure 142.21
Pathology of Bowen disease showing loss of polarity of the epidermis and the presence of atypical mitoses and giant cells.
Figure c142/f025
Figure 142.25
Superficial basal cell carcinoma mimicking Bowen disease.
Figure c142/f029
Figure 142.29
(a) Large confluent areas of bowenoid papulosis. (b) Following treatment for 6 weeks with 5% imiquimod cream. (c) Marked improvement seen at follow‐up...
Figure c142/f033
Figure 142.33
Key signalling pathways involved in the formation of squamous cell carcinomas (SCCs). Mutations induced by UVB exposure can perturb multiple cellular ...
Figure c142/f037
Figure 142.37
Well‐differentiated squamous cell carcinoma with even circumscribed edge and central crusting.
Figure c142/f041
Figure 142.41
Squamous cell carcinoma (SCC) management algorithm. (Annex 3 reproduced and adapted with permission from the Scottish Intercollegiate Guidelines Netwo...
Figure c142/f002
Figure 142.2
Actinic keratosis.
Figure c142/f006
Figure 142.6
Squamous cell carcinoma showing hyperkeratosis with a raised nodule.
Figure c142/f010
Figure 142.10
‘Low‐risk’ disease characterized by few thin actinic keratoses.
Figure c142/f014
Figure 142.14
(a) Actinic keratoses before treatment with 5% 5‐fluorouracil cream. (b) Three weeks into treatment with daily 5% 5‐fluorouracil cream. (c) Post‐treat...
Figure c142/f018
Figure 142.18
Pathology of post‐ionizing radiation keratosis.
Figure c142/f022
Figure 142.22
Bowen disease.
Figure c142/f026
Figure 142.26
Squamous cell carcinoma with hyperkeratosis and raised thickened edge.
Figure c142/f030
Figure 142.30
Dermoscopy of Bowen disease showing irregular erythematous base, mild hyperkeratosis with vascular structures throughout the lesion.
Figure c142/f034
Figure 142.34
Pathological features of well‐differentiated, early invasive squamous cell carcinoma, showing differentiated keratinocytes invading the underlying der...
Figure c142/f038
Figure 142.38
Seborrhoeic keratosis mimicking squamous cell carcinoma.
Figure c142/f042
Figure 142.42
(a) Pathology of keratoacanthoma showing endophytic growth pattern with epidermal lipping and no evidence of dermal invasion (×20). (Courtesy of Dr M...
Figure c142/f003
Figure 142.3
Lichenoid actinic keratoses.
Figure c142/f007
Figure 142.7
Bowen disease which is usually larger than actinic keratoses with an irregular erythematous base.
Figure c142/f011
Figure 142.11
‘High‐risk’ disease characterized by multiple thick actinic keratoses and previously excised non‐melanoma skin cancer.
Figure c142/f015
Figure 142.15
(a) Hyperkeratotic actinic keratosis before treatment with 5% imiquimod cream. (b) Four weeks into treatment with 5% imiquimod cream. (c) Post‐treatme...
Figure c142/f019
Figure 142.19
Cornoid lamella with parakeratotic column overlying epidermal dyskeratotic and vacuolated cells, representing the clinically visible raised margin see...
Figure c142/f023
Figure 142.23
Multiple areas of Bowen disease on the lower leg.
Figure c142/f027
Figure 142.27
Discoid dermatitis of the lower leg. (Courtesy of Dr W. A. D. Griffiths, Epsom Hospital, Surrey, UK.)
Figure c142/f031
Figure 142.31
Bowen disease management algorithm. *Treatment should be decided following discussion with patient, treatment availability and local expertise with th...
Figure c142/f035
Figure 142.35
Multiple invasive squamous cell carcinomas in a patient with a history of exposure to arsenic.
Figure c142/f039
Figure 142.39
Well‐differentiated squamous cell carcinoma on the helix of the ear (high‐risk site).
Figure c142/f043
Figure 142.43
Scarring seen in a patient with multiple self‐healing squamous epitheliomas.
Figure c142/f004
Figure 142.4
Seborrhoeic keratosis.
Figure c142/f008
Figure 142.8
(a,b) Keratoacanthoma which is often larger and more hyperkeratotic than actinic keratosis.
Figure c142/f012
Figure 142.12
‘High‐risk’ disease characterized by multiple thick actinic keratoses in an immunosuppressed patient on ciclosporin.
Figure c142/f016
Figure 142.16
Typical cutaneous horn. Underlying this lesion, a carcinoma in situ was identified after biopsy.
Figure c142/f020
Figure 142.20
Disseminated superficial actinic porokeratosis on the lower legs.
Figure c142/f024
Figure 142.24
Periungual Bowen disease.
Figure c142/f028
Figure 142.28
(a,b) Plaque with thick scale. Examination elsewhere shows typical scaly plaques seen in psoriasis.
Figure c142/f032
Figure 142.32
(a) Bowen disease before treatment with liquid nitrogen cryotherapy. (b) Dermoscopy prior to treatment, showing crusting with central vascular structu...
Figure c142/f036
Figure 142.36
Raised erythematous invasive squamous cell carcinoma in an elderly patient on a light‐exposed site.
Figure c142/f040
Figure 142.40
Poorly differentiated squamous cell carcinoma presenting as a nodule and lacking typical keratin centre.