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Figure c143/f001
Figure 143.1
Large congenital naevus.
Figure c143/f005
Figure 143.5
(a,b) Superficial spreading melanoma (late presentation).
Figure c143/f009
Figure 143.9
Acral lentiginous melanoma of the sole (late presentation).
Figure c143/f013
Figure 143.13
Amelanotic melanoma. (a) Amelanotic superficial spreading melanoma. (b) Amelanotic nodular.
Figure c143/f017
Figure 143.17
Acral lentiginous melanoma with typical lentiginous pattern.
Figure c143/f021
Figure 143.21
Malignant blue naevus.
Figure c143/f025
Figure 143.25
(a,b) Pigmented melanoma skin metastasis. In a subset of melanoma patients mostly with primary melanoma on the lower extremity, melanoma metastases de...
Figure c143/f029
Figure 143.29
(a,b) Rash secondary to BRAF inhibitor. A patient treated with the selective BRAF inhibitor vemurafenib (after 2 weeks of treatment) has developed...
Figure c143/f002
Figure 143.2
Atypical/dysplastic naevi.
Figure c143/f006
Figure 143.6
(a–c) Nodular melanomas.
Figure c143/f010
Figure 143.10
Acral lentiginous melanoma in the nail area. Early presentation as a longitudinal melanonychia.
Figure c143/f014
Figure 143.14
(a,b) Amelanotic acral lentiginous melanomas.
Figure c143/f018
Figure 143.18
Lentigo maligna melanoma.
Figure c143/f022
Figure 143.22
Breslow depth.
Figure c143/f026
Figure 143.26
Amelanotic melanoma skin metastasis. Amelanotic melanoma skin metastases require a very careful skin examination, as they can be easily missed.
Figure c143/f030
Figure 143.30
Positron emission tomography‐computed tomography (PET‐CT) scans of an advanced BRAF mutated melanoma patient treated with selective BRAF inhibitor v...
Figure c143/f003
Figure 143.3
Atypical/dysplastic naevus syndrome.
Figure c143/f007
Figure 143.7
 (a–e) Lentigo maligna melanomas.
Figure c143/f011
Figure 143.11
(a–c) Acral lentiginous melanomas in the nail area. Late presentation.
Figure c143/f015
Figure 143.15
Regressive mealnomas. (a) Partial regression. (b) Quasi‐total regression.
Figure c143/f019
Figure 143.19
Superficial spreading melanoma.
Figure c143/f023
Figure 143.23
(a–c) Sentinel lymph node biopsy allows detection of melanoma micrometastases in regional lymph nodes. Radioactive tracer and dye are injected intrade...
Figure c143/f027
Figure 143.27
Targeting signalling pathways in melanoma. The mitogen‐activated protein kinase (MAPK) pathway is one of the most important signalling pathways in mel...
Figure c143/f004
Figure 143.4
(a–c) Superficial spreading melanoma (early presentation).
Figure c143/f008
Figure 143.8
(a–d) Acral lentiginous melanomas.
Figure c143/f012
Figure 143.12
Mucosal melanomas. (a) Anal; (b) oral.
Figure c143/f016
Figure 143.16
Nodular melanoma.
Figure c143/f020
Figure 143.20
Desmoplastic melanoma.
Figure c143/f024
Figure 143.24
Treatment algorithm of advanced melanoma in a tertiary referral centre. The landscape of systemic treatment options in metastatic melanoma has rapidly...
Figure c143/f028
Figure 143.28
The mitogen‐activated protein kinase (MAPK) pathway. This pathway is a key regulator for gene expression that drives melanocytic gene differentiation ...