Schematic representation of three hypothalamopituitary axes that impact on human skin: key elements of the central hypothalamopituitary–adrenal (HPA) ...
Cutis verticis gyrata.
Addisonian pigmentation of the palmar creases 37 years after bilateral adrenalectomy for Cushing disease from ACTH‐producing pituitary adenoma (Nelson...
Striae due to obesity in a young man.
Neurosarcoidosis with hypopituitarism presenting as a rash. A diagnosis of cutaneous and pulmonary sarcoidosis was readily established in a 35‐year‐ol...
The human hair follicle as a (neuro‐) endocrine microcosm. This schematic drawing of a human anagen VI scalp hair follicle indicates the main intrafol...
Histamine‐evoked ‘geographical’ pattern of flushing due to foregut carcinoid tumour. (Courtesy of Professor M. Greaves, London, UK.)
Pigmentation of (a) the gingivae and (b) the tongue in a woman who presented with darkening skin due to Addison disease.
Acanthosis nigricans, skin tags and striae in a 41‐year‐old obese male with type 2 diabetes.
Gynaecomastia due to long‐term spironolactone therapy given for hypertension.
A patient with Graves disease with pretibial myxoedema and exophthalmos.
Acromegaly: note the coarse features, severe acne and seborrhoea.
An 18‐year‐old male with pituitary Cushing disease followed by hypopituitarism. (a) Obesity and gynaecomastia. (b) Insulin resistance with acanthosis ...
Necrolytic migratory erythema. (Courtesy of Dr Kristian Thomsen, Finsen Institute, Copenhagen, Denmark.)