Figure 29.1
Diagnoses of infectious syphilis made at GUM clinics in England, Scotland and Wales peaked towards the end of World War II, and then fell sharply in t...
Figure 29.5
Primary and secondary syphilis by sex and sexual behaviour in selected areas of the USA, 2007–2011. MSM, men who have sex with men; MSW, men who have ...
Figure 29.9
Treponema pallidum showing typical morphology.
Figure 29.13
(a) Bilateral early chancres of the labia majora. (b) Chancre of the fourchette with surrounding oedema. This patient also had accompanying gonorrhoea...
Figure 29.17
Syphilitic leukoderma showing depigmentation at sites of healed secondary lesions on the neck and upper back.
Figure 29.21
Oral lesions of secondary syphilis. (a) Split papules at the angle of the mouth. (b) Mucous patches on the buccal mucosa.
Figure 29.25
Mucosal lesions of tertiary syphilis. (a) Early gumma of the hard palate. (b) Perforated gumma of the hard palate.
Figure 29.29
Neurosyphilis causing Argyll–Robertson pupils of the eyes. The abdomen shows multiple scars after surgical intervention for tabetic crises mimicking a...
Figure 29.33
(a) Early congenital syphilis showing serous nasal discharge from nasopharyngitis – ‘syphilitic snuffles’. (b) Congenital syphilitic facies with saddl...
Figure 29.37
Widespread syphilitic osteitis, periostitis and destructive metaphysitits of the long bones.
Figure 29.41
Clutton's joints in late congenital syphilis.
Figure 29.2
Diagnoses of infectious syphilis by gender in England, 2003–2012. (Data from GUMCAD Public Health England, http://www.hpa.org.uk/gumcad . © Crown co...
Figure 29.6
Secondary syphilis showing psoriasiform hyperplasia of the epidermis with spongiosis and interface change with abundant plasma cells.
Figure 29.10
Immunofluorescent image of Treponemal pallidum .
Figure 29.14
(a) Primary chancre of the upper lip showing a typical button‐like induration. (b) Primary chancre of the left tonsil.
Figure 29.18
Secondary syphilis showing papular syphilides on (a) the forearms and (b) the trunk.
Figure 29.22
(a) Papular lesions of the face extending into the hairline. (b) Moth‐eaten alopecia in secondary syphilis associated with papular lesions of the scal...
Figure 29.26
Visceral lesions of tertiary syphilis. (a) Gumma of the liver causing portal vein obstruction. (b) Portal hypertension with caput medusa caused by hep...
Figure 29.30
Tabes dorsalis. (a) Charcot's (neuropathic) joints of the knee. (b) X‐ray of Charcot's joints of the knee showing a loss of normal alignment with mult...
Figure 29.34
Early congenital syphilis with widespread papular and vesicular lesions covering the body.
Figure 29.38
Dactylitis of the little finger in late congenital syphilis.
Figure 29.42
Early congenital syphilis showing osteitis of the skull bones (arrow) causing a worm‐eaten appearance.
Figure 29.3
Diagnoses of infectious syphilis by age and gender in England, 2012. (Data from GUMCAD Public Health England, http://www.hpa.org.uk/gumcad . © Crown...
Figure 29.7
Secondary syphilis. Immunohistochemistry shows numerous spirochaetes within the epidermis.
Figure 29.11
Penile chancres. (a) Primary syphilis showing chancres on the glans and shaft of the penis. (b) Taking specimens for dark ground microscopy from a pen...
Figure 29.15
Syphilitic paronychia caused by a primary chancre of the middle finger.
Figure 29.19
Secondary syphilis showing psoriasiform lesions of the palms.
Figure 29.23
Syphilitic iritis causing circumcorneal injection of the blood vessels.
Figure 29.27
Chronic interstitial glossitis with bilateral squamous carcinoma.
Figure 29.31
Typical serological responses at different stages and in response to treatment of syphilis. FTA, fluorescent treponemal antibody; Ig, immunoglobulin; ...
Figure 29.35
Early congenital syphilis with ruptured bullous pemiphigioid lesions on the soles of the feet.
Figure 29.39
Late congenital syphilis with gummata on the forehead and scalp.
Figure 29.43
Malformations of the secondary dentition in late congenital syphilis. (a) Hutchinson's teeth. (b) Close‐up of Hutchinson's incisors.
Figure 29.4
Reported cases of syphilis by stage of infection in the USA, 1941–2011. (Courtesy of Centers for Disease Control and Prevention, Atlanta, GA, USA.)
Figure 29.8
Treponema pallidum on dark ground microscopy.
Figure 29.12
Anal lesion in syphilis.
Figure 29.16
Secondary syphilis. (a) Extensive truncal maculopapular rash. (b) Macular rash with lesions following the skin lines of cleavage. (c) Papulosquamous p...
Figure 29.20
Condylomata lata of secondary syphilis: (a, b) perianal; (c) round the groin; (d) perivulval; (e) on the penile shaft with surrounding depigmentation ...
Figure 29.24
Skin lesions in tertiary syphilis. (a) Nodular gummata of the arm. (b) Psoriasiform gummata on the neck. (c) Psoriasiform gummata of the leg before (r...
Figure 29.28
Cardiovascular syphilis. (a) Chest X‐ray showing a dilated aorta with linear calcification in the wall of the ascending aorta. (b) Chest X‐ray showing...
Figure 29.32
Reported cases of congenital syphilis (CS) among infants by year of birth and rates of primary and secondary syphilis (P&S) among women in the USA, 20...
Figure 29.36
Wimberger's sign (arrow) – destruction of the proximal metaphyses of the tibiae.
Figure 29.40
Early congenital syphilis with chorioretinitis and optic atrophy.
Figure 29.44
Moon's molars showing a dome‐shaped malformation and loss of cusps (arrows).
