Schematic of the pathophysiology of atopic eczema.
Atopic eczema: infantile phase.
Atopic ’dirty neck’; reticulate pigmentation on the neck of a patient with longstanding atopic eczema.
(a) Discoid eczema lesions in an atopic child. (b) Discoid lesions on the face. Saliva is a common irritant in young children. (c) Discoid lesion aggr...
(a) Follicular lichenification on the surface. (b) Atopic hand eczema.
The incidence of atopic respiratory symptoms in 1200 patients with atopic eczema. (From Rajka 1960–1 [ ]. Reproduced with permission from Medical Jou...
Spectrum of trigger factors at different ages. (Adapted from Katayama et al . 2011 [ ]. Reproduced with permission from the Japanese Society of Alle...
(a,b) Worldwide change in atopic eczema symptom prevalence between International Study of Asthma and Allergies in Childhood (ISAAC) Phases 1 and 3. SE...
(a) Dermatitis causing hypopigmentation. (b) Extensor dermatitis in an infant.
Atopic eczema: erythema, papules, excoriations, crusting and secondary infection but, in this case, little lichenification.
Atopic eczema of the fingers of a child.
Kaposi varicelliform eruption: eczema herpeticum.
(a) Lip‐lick cheilitis. (b) Lip‐lick dermatitis with mild impetiginization. (c) Lip‐lick dermatitis with hyperpigmentation.
(a) Airborne facial eczema with lip‐lick cheilitis. (b) Airborne facial dermatitis with lip‐lick cheilitis. (c) Periorbital dermatitis in the older ch...
Pathophysiology of atopic eczema (AE). LN, lymph node; TSLP, thymic stromal lymphopoietin.
(a) Lichenification, crusting and excoriation in the popliteal fossae. (b) Postinflammatory pigmentation. (c) Flexural dermatitis causing hypopigmenta...
Marked lichenification on the knees of an African child. The popliteal fossae were spared.
Nail involvement in atopic eczema in childhood.
Periorbital dermatitis with Dennie–Morgan fold.
Trigger factors for atopic eczema.
Filaggrin (FLG). A representation of the clinical features identified in FLG homozygote or compound hetrerozygote mutations (FLG –/–) versus heteroz...
Flexural atopic eczema of the wrist in a child.
Persistent lichenification in an extensor distribution.
Adult flexural dermatitis.
Atopic eczema treatment algorithm. TCI, topical calcineurin inhibitors; TCS, topical corticosteroids.