(a) Scleromyxoedema. The typical triad of microscopic features with diffuse dermal mucin deposition, fibroblast proliferation and fibrotic collagen. (...
Scleromyxoedema. Deep longitudinal erythematous folding on the forehead (leonine face). (Courtesy of D. Metze, MD, Munster, Germany.)
Acral persistent papular mucinosis. Multiple skin‐coloured papules on the dorsal aspect of the hand.
Pretibial myxoedema with diffuse non‐pitting oedema and plaque‐like lesions on the legs.
(a) Papular and nodular mucinosis in connective tissue disease. (b) Abundant mucin deposition throughout the reticular dermis (Alcian blue stain).
(a) Pinkus follicular mucinosis. A sharply demarcated erythematous plaque with follicular prominence. (b) Alopecic plaque in follicular mucinosis. (c)...
Scleromyxoedema. Widespread eruption of closely spaced papules on the back of the hand.
Scleromyxoedema. Deep furrowing on the shoulders and back (Shar‐Pei sign).
Discrete papular lichen myxoedematosus. Mucinous skin‐coloured papules on the trunk.
Pretibial myxoedema of nodular type.
Self‐healing cutaneous mucinosis. Mucinous subcutaneous nodules and papules on the periarticular areas of the hand in a child.
Scleromyxoedema. Papules on the thigh.
Scleromyxoedema. ‘Doughnut sign’ on the proximal interphalangeal joints.
Reticular erythematous mucinosis in the midline of the chest and abdomen.
Elephantiasic pretibial myxoedema. (Courtesy of B. Cribier, MD, Strasbourg, France.)
Cutaneous focal mucinosis. A solitary whitish papule with cystic appearance.
Scleromyxoedema. Papules behind the ear.
(a) Microscopic features of acral persistent papular mucinosis. Focal mucin accumulation in the upper dermis sparing a grenz zone without fibroblast p...
Scleredema in a diabetic patient with firm non‐pitting oedema and induration on the upper back, neck and shoulders on erythematous background.
Localized myxoedema on the preradial area. Note the orange peel appearance. (Courtesy of S. Verma, MD, Vadodara, Gujarat, India.)
Digital myxoid cyst. A translucent dome‐shaped nodule on the distal interphalangeal joint of the finger.