Figure 74.1
(a) Generalized lipoatrophy of the upper and lower limbs. (b) Severe lipoatrophy of the buttocks. (From Martinez et al . 2000 [ ]. Reproduced with p...
Figure 74.5
A pro‐opiomelanocortin (POMC) deficient patient and his unaffected sister showing a lack of red hair. The arrows show a C202T mutation leading to a pr...
Figure 74.9
Lipoedema. (From Langendoen et al . 2009 [ ]. Reproduced with permission of John Wiley & Sons.)
Figure 74.2
Clinical features of Albright hereditary osteodystrophy: (a) obesity; (b) round facies; (c) hypoplastic skin lesion; and (d) detailed view of a skin l...
Figure 74.6
Multiple lipomas in association with Proteus syndrome. (From Smithson and Winter 2004 [ ]. Reproduced with permission of John Wiley & Sons.)
Figure 74.3
X‐ray showing brachydactyly in Albright hereditary osteodystrophy [ ].
Figure 74.7
Hereditary panniculitis caused by homozygous ZZ α 1 ‐antitrypsin deficiency. (From Chowdhury et al . 2002 [ ]. Reproduced with permission of John Wi...
Figure 74.4
Gene structure and post‐translational processing of pro‐opiomelanocortin (POMC). POMC in mammals consists of three exons, of which exons 2 and 3 are t...
Figure 74.8
Alpha‐1‐antitrypsin‐deficiency panniculitis (phenotype PiZZ). (From Yesudian et al . 2004 [ ]. Reproduced with permission of John Wiley & Sons Ltd.)...
