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Figure c08/f001
Figure 08.1
Histopathological features of skin inflammation. (a) Subacute dyshidrosiform dematitis with intraepidermal intercellular oedema (spongiosis), and accu...
Figure c08/f005
Figure 08.5
Role of macrophages for innate and acquired immune function. (Modified with permission from Gordon S. Alternative activation of macrophages. Nature R...
Figure c08/f009
Figure 08.9
The classification of hypersensitivity reactions according to Coombs and Gell. Reaction type IV involves direct cellular interaction and differs there...
Figure c08/f002
Figure 08.2
Epithelial γδ T‐cell interactions with keratinocytes in the epidermis. Distinct functional interactions occur between dendritic epidermal T cells (DET...
Figure c08/f006
Figure 08.6
Classification of innate lymphoid cells (ILCs) into three groups on the basis of their functional characteristics. The proposed classification of ILCs...
Figure c08/f010
Figure 08.10
Structure of immunoglobulin E (IgE). It consists of two heavy chains, each with five immunoglobulin domains, and two light chains, containing two immu...
Figure c08/f003
Figure 08.3
Neutrophil emigration. (a) Rolling: cells roll over the endothelium by brief non‐adherent contacts via the selectins, particularly L‐selectin. The int...
Figure c08/f007
Figure 08.7
Activation of naive T lymphocytes by interaction with dendritic antigen‐presenting cell. Signal 1 comes from interaction of the T‐cell receptor (TCR) ...
Figure c08/f011
Figure 08.11
Differentiation pathways of CD4+ Th cell subsets. Depending on the adjuvant effects of the substances co‐exposed with the antigen and on the status of...
Figure c08/f004
Figure 08.4
A proposed mechanistic model on how SHARPIN regulates tumour necrosis factor (TNF)‐induced nuclear factor (NF)‐κB activation through linear ubiquitina...
Figure c08/f008
Figure 08.8
Differentiation of CD4+ T lymphocytes. Precursor naive T cells have the potential to differentiate into either Th1, Th2 or Th17 cells, depending upon ...