Part 1, Reference for Chapter 8: Inflammation, Immunology and Allergy
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Clinical characteristics of inflammation and phases of inflammation
- 1 Neuronal control of skin function: the skin disease as a neuroendocrine organ. Physiol Rev 2006 Oct;86(4):1309–79. Cross Ref link Pubmed link , , , , .
- 2 Tachykinins and their receptors: contributions to physiological control and the mechanism of disease. Physiol Rev 2014 Jan;94(1):265–301. Cross Ref link Pubmed link , , , , .
- 3 Pain and itch: insights into the neural circuits of aversive somatosensation in health and disease. Curr Opin Neurobiol 2011 Dec;21(6):880–7. Cross Ref link Pubmed link .
- 4 Origin and physiological roles of inflammation. Nature 2008 Jul 24;454:428–35. Cross Ref link Pubmed link .
- 5 A mechanism for the initiation of allergen‐induced T helper type 2 responses. Nat Immunol 2008 Mar;9:310–18. Cross Ref link Pubmed link , , , .
- 6 Activation and regulation of the inflammasomes. Nat Rev Immunol 2013 Jun;13(6):397–411. Cross Ref link Pubmed link , , .
- 7 Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol 2002 Jul;3(7):673–80. Cross Ref link Pubmed link , , , et al.
- 8 Resolution phase of inflammation: novel endogenous anti‐inflammatory and proresolving lipid mediators and pathways. Annu Rev Immunol 2007;25:101–37. Cross Ref link Pubmed link .
- 9 Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008 May 2;320:674–7. Cross Ref link Pubmed link , , , , , .
- 10 Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006 Mar 9;440:228–32. Cross Ref link Pubmed link , , , et al.
- 11 RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 1999 Jun 25;97:889–901. Cross Ref link Pubmed link , , , et al.
- 12 Mrp8 and Mrp14 are endogenous activators of Toll‐like receptor 4, promoting lethal, endotoxin‐induced shock. Nat Med 2007 Sep;13:1042–9. Cross Ref link Pubmed link , , , et al.
- 13 The inflammatory response to cell death. Annu Rev Pathol 2008;3:99–126. Cross Ref link Pubmed link , .
- 14 Active caspase‐1 is a regulator of unconventional protein secretion. Cell 2008 Mar 7;132:818–31. Cross Ref link Pubmed link , , , .
- 15 Role of NF‐κB in epithelial biology. Immunol Rev 2012 Mar;246(1):346–58. Cross Ref link Pubmed link .
- 16 The role of dendritic cells in autoimmunity. Nat Rev Immunol 2013 Aug;13(8):566–77. Cross Ref link Pubmed link , , , .
- 17 Lesional dentritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T‐cell subsets. J Allergy Clin Immunol 2011 Sep;128(3):574–82. Cross Ref link Pubmed link , , , et al.
Cellular components of cutaneous inflammation
Epidermis
- 18 Plaque psoriasis vs. atopic dermatitis and lichen planus: a comparison for lesional T‐cell subsets, epidermal proliferation and differentiation. Br J Dermatol 2005 Jul;153:72–8. Cross Ref link Pubmed link , , .
- 19 Impaired sphingomyelinase activity and epidermal differentiation in atopic dermatitis. J Invest Dermatol 2004 Jun;122:1423–31. Cross Ref link Pubmed link , , , et al.
- 20 The skin: an indispensable barrier. Exp Dermatol 2008 Dec;17:1063–72. Cross Ref link Pubmed link , , .
- 21 PPAR and LXR activators regulate ABCA12 expression in human keratinocytes. J Invest Dermatol 2008 Jan;128:104–9. Cross Ref link Pubmed link , , , et al.
- 22 Thematic review series: skin lipids. Peroxisome proliferator‐activated receptors and liver X receptors in epidermal biology. J Lipid Res 2008 Mar;49:499–509. Cross Ref link Pubmed link , , , , .
- 23 Peroxisome proliferator‐activated receptors (PPARs) and the human skin: importance of PPARs in skin physiology and dermatologic diseases. Am J Clin Dermatol 2008;9:15–31. Cross Ref link Pubmed link , , , .
- 24 Involvement of MIF in basement membrane damage in chronically UVB‐exposed skin in mice. PLOS One 2014 Feb 21:9(2):e89569. Cross Ref link Pubmed link , , , , .
- 25 CXC chemokines and their receptors: a case for a significant biological role in cutaneous wound healing. Histol Histopathol 2008 Nov;23:1399–407. Pubmed link , .
- 26 Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol 2002 Jul;3:673–80. Cross Ref link Pubmed link , , , et al.
- 27 Impaired IFN‐gamma‐dependent inflammatory responses in human keratinocytes overexpressing the suppressor of cytokine signaling 1. J Immunol 2002 Jul 1;169:434–42. Cross Ref link Pubmed link , , , , .
- 28 Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healing. J Cell Biol 2000 Oct 16;151:209–20. Cross Ref link Pubmed link , , , et al.
- 29 Infliximab for psoriasis. J Am Acad Dermatol 2003 Aug;49:S112–17. Cross Ref link Pubmed link .
- 30 Early inflammatory processes in the skin. Curr Mol Med 2013 Sep;13(8):1250–69. Cross Ref link Pubmed link , , .
- 31 Ultraviolet radiation effects on the proteome of skin cells. Adv Exp Med Biol 2013;990:111–19. Cross Ref link Pubmed link , .
- 32 Interplay between CXCR2 and BLT1 facilitates neutrophil infiltration and resultant keratinocyte activation in a murine model of imiquimod‐induced psoriasis. J Immunol 2014 May 1;192(9):4361–9. Cross Ref link Pubmed link , , , et al.
- 33 In situ demonstration of phosphorylated c‐jun and p38 MAP kinase in epidermal keratinocytes following ultraviolet B irradiation of human skin. J Pathol 2001 Feb;193:248–55. Cross Ref link Pubmed link , , , , , .
- 34 Reversal of ultraviolet radiation‐induced immune suppression by recombinant interleukin‐12: suppression of cytokine production. Immunology 2000 Sep;101:90–6. Cross Ref link Pubmed link , , .
- 35 A role for NF‐kappaB‐dependent gene transactivation in sunburn. J Clin Invest 2000 Jun;105:1751–9. Cross Ref link Pubmed link , , , et al.
- 36 Keratinocytes in epidermal immune responses. Curr Opin Allergy Clin Immunol 2001 Oct;1:469–76. Cross Ref link Pubmed link , , .
- 37 The enhanced monocyte adhesiveness after UVB exposure requires ROS and NF‐kappaB signaling in human keratinocyte. J Biochem Mol Biol 2006 Sep 30;39:618–25. Cross Ref link Pubmed link , , , et al.
- 38 Role of ROS and MAPK in TPA‐induced ICAM‐1 expression in the myeloid ML‐1 cell line. J Cell Biochem 2007 Mar 1;100:1010–21. Cross Ref link Pubmed link , , , .
- 39 Microarray analysis identifies interferon‐inducible genes and Stat‐1 as major transcriptional targets of human papillomavirus type 31. J Virol 2000 May;74:4174–82. Cross Ref link Pubmed link , .
- 40 CD44 as a receptor for colonization of the pharynx by group A Streptococcus. J Clin Invest 2000 Oct;106:995–1002. Cross Ref link Pubmed link , , .
- 41 The influence of heterologous combinations of antiserum and enzyme‐labeled estrogen on the characteristics of estrogen enzyme‐immunoassays. Immunochemistry 1975 Aug;12:667–70. Cross Ref link Pubmed link , .
- 42 Kindler syndrome in mice and men. Cancer Biol Ther 2014 Jun 11;15(9):1198–207. Cross Ref link Pubmed link , .
- 43 Kindler syndrome: a focal adhesion genodermatosis. Br J Dermatol 2009 Feb;160:233–42. Cross Ref link Pubmed link , , , et al.
- 44 Proteases and proteomics: cutting to the core of human skin pathologies. Proteomics Clin Appl 2014 Jun;8(5–6):389–402. Cross Ref link Pubmed link , , , .
- 45 β1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progeny. PLOS One 2013 Dec 27;8(12):e84356. Cross Ref link Pubmed link , , , et al.
- 46 Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells. Nat Med 2006 Dec;12:1397–402. Cross Ref link Pubmed link , , , et al.
Dermis
- 47 The chemokine receptor CCR3 participants in tissue remodeling during atopic skin inflammation. J Dermatol Sci 2013 Jul;71(1):12–21. Cross Ref link Pubmed link , , , et al.
- 48 Collagen lattice effects on fibroblast arachidonic acid metabolism. J Cell Physiol 1989 May;139:392–7. Cross Ref link Pubmed link .
- 49 Contraction and organization of collagen gels by cells cultured from periodontal ligament, gingiva and bone suggest functional differences between cell types. J Cell Sci 1981 Aug;50:299–314. Pubmed link , , .
- 50 Extracellular matrix organization modulates fibroblast growth and growth factor responsiveness. Exp Cell Res 1989 Jun;182:572–82. Cross Ref link Pubmed link , , .
- 51 Modulation of cellular biosynthetic activity in the retracting collagen lattice. Eur J Cell Biol 1987 Dec;45:44–50. Pubmed link , , .
- 52 Association between tension and orientation of periodontal ligament fibroblasts and exogenous collagen fibres in collagen gels in vitro. J Cell Sci 1982 Dec;58:125–38. Pubmed link , , .
- 53 Fibroblasts, myofibroblasts, and wound contraction. J Cell Biol 1994 Feb;124:401–4. Cross Ref link Pubmed link .
- 54 Extracellular matrix alters PDGF regulation of fibroblast integrins. J Cell Biol 1996 Jan;132:239–49. Cross Ref link Pubmed link , .
- 55 Decreased level of PDGF‐stimulated receptor autophosphorylation by fibroblasts in mechanically relaxed collagen matrices. J Cell Biol 1993 Aug;122:663–72. Cross Ref link Pubmed link , .
- 56 Abnormally differenitating keratinocytes in the epidermis of systemic sclerosis patients show enhanced secretion of CCN2 and S100A9. J Invest Dermatol 2014 Nov;134(11):2693–702. Cross Ref link Pubmed link , , , , .
- 57 Decreased expression of alpha 2 beta 1 integrin in scleroderma fibroblasts. Exp Dermatol 1996 Feb;5:57–63. Cross Ref link Pubmed link , , , , , .
- 58 Impaired regulation of collagen pro‐alpha 1(I) mRNA and change in pattern of collagen‐binding integrins on scleroderma fibroblasts. J Invest Dermatol 1993 Aug;101:216–21. Cross Ref link Pubmed link , , , .
- 59 Fibrogenic cytokines: the role of immune mediators in the development of scar tissue. Immunol Today 1991 Jan;12:17–23. Cross Ref link Pubmed link .
- 60 The relationship between allergen‐induced tissue eosinophilia and markers of repair and remodeling in human atopic skin. J Immunol 2002 Oct 15;169:4604–12. Cross Ref link Pubmed link , , , , , .
- 61 Neuropeptides and sebaceous glands. Eur J Dermatol 2002 Sep–Oct;12:422–7. Pubmed link , , .
- 62 J Pathol 2014 Jul;233(3):294–307. Cross Ref link Pubmed link , , , et al.
- 63 Blockade of mast cell activation reduces cutaneous scar formation. PLOS One 2014 Jan 22;9(1):e85226. Cross Ref link Pubmed link , , , , .
- 64 The enzyme Cyp26b1 mediates inhibition of mast cell activation by fibroblasts to maintain skin‐barrier homeostasis. Immunity 2014 Apr 17;40(4):530–41. Cross Ref link Pubmed link , , , et al.
Epidermal and dermal cell–cell communication during inflammation
Endothelial cells, Selectins
- 65 Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1. J Exp Med 1990 Jul 1;172:263–72. Cross Ref link Pubmed link , , , et al.
- 66 A platelet membrane protein expressed during platelet activation and secretion. Studies using a monoclonal antibody specific for thrombin‐activated platelets. J Biol Chem 1984 Jul 25;259:9121–6. Pubmed link , , , , .
- 67 GMP‐140, a platelet alpha‐granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel–Palade bodies. J Clin Invest 1989 Jul;84:92–9. Cross Ref link Pubmed link , , , , .
- 68 Oncostatin M is a proinflammatory mediator. In vivo effects correlate with endothelial cell expression of inflammatory cytokines and adhesion molecules. J Clin Invest 1997 Jul 1;100:158–68. Cross Ref link Pubmed link , , , et al.
- 69 Interleukin 4 or oncostatin M induces a prolonged increase in P‐selectin mRNA and protein in human endothelial cells. J Exp Med 1996 Jul 1;184:81–92. Cross Ref link Pubmed link , , , , .
- 70 Interleukin‐13 induces PSGL‐1/P‐selectin‐dependent adhesion of eosinophils, but not neutrophils, to human umbilical vein endothelial cells under flow. Blood 2000 May 15;95:3146–52. Pubmed link , , , , .
- 71 Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell 1991 May 31;65:859–73. Cross Ref link Pubmed link , .
- 72 Induction of superoxide anion production from monocytes an neutrophils by activated platelets through the P‐selectin‐sialyl Lewis X interaction. J Leukoc Biol 1994 Nov;56:583–7. Pubmed link , , , , .
- 73 Coexpression of GMP‐140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils. J Cell Biol 1991 Oct;115:223–34. Cross Ref link Pubmed link , , , , , .
- 74 The selectins: vascular adhesion molecules. FASEB J 1995 Jul;9:866–73. Pubmed link , , , .
- 75 Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP‐140. J Biol Chem 1989 May 15;264:7768–71. Pubmed link , , , , .
- 76 P‐selectin glycoprotein ligand‐1 is broadly expressed in cells of myeloid, lymphoid, and dendritic lineage and in some nonhematopoietic cells. Blood 1996 Oct 15;88:3010–21. Pubmed link , , , , , .
- 77 Targeted gene disruption demonstrates that P‐selectin glycoprotein ligand 1 (PSGL‐1) is required for P‐selectin‐mediated but not E‐selectin‐mediated neutrophil rolling and migration. J Exp Med 1999 Dec 20;190:1769–82. Cross Ref link Pubmed link , , , et al.
- 78 CD24 mediates rolling of breast carcinoma cells on P‐selectin. FASEB J 1998 Sep;12:1241–51. Pubmed link , , , et al.
- 79 Engagement of P‐selectin glycoprotein ligand‐1 enhances tyrosine phosphorylation and activates mitogen‐activated protein kinases in human neutrophils. J Biol Chem 1997 Nov 7;272:28750–6. Cross Ref link Pubmed link , , , .
- 80 T cell adhesion to P‐selectin induces tyrosine phosphorylation of pp125 focal adhesion kinase and other substrates. J Immunol 1997 Feb 1;158:1061–7. Pubmed link , , , et al.
- 81 Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science 1989 Mar 3;243:1160–5. Cross Ref link Pubmed link , , , .
- 82 Substance P induces the expression of an endothelial‐leukocyte adhesion molecule by microvascular endothelium. J Invest Dermatol 1990 Apr;94:492–5. Cross Ref link Pubmed link , , .
- 83 Degranulation of human mast cells induces an endothelial antigen central to leukocyte adhesion. Proc Natl Acad Sci U S A 1989 Nov;86:8972–6. Cross Ref link Pubmed link , , , .
- 84 The E‐selectin‐ligand ESL‐1 is a variant of a receptor for fibroblast growth factor. Nature 1995 Feb 16;373:615–20. Cross Ref link Pubmed link , , , et al.
- 85 The P‐selectin glycoprotein ligand functions as a common human leukocyte ligand for P‐ and E‐selectins. J Biol Chem 1995 May 12;270:11662–70. Cross Ref link Pubmed link , , , et al.
- 86 The neutrophil selectin LECAM‐1 presents carbohydrate ligands to the vascular selectins ELAM‐1 and GMP‐140. Cell 1991 Sep 6;66:921–33. Cross Ref link Pubmed link , , , , , .
- 87 Endothelial‐leukocyte adhesion molecule 1 stimulates the adhesive activity of leukocyte integrin CR3 (CD11b/CD18, Mac‐1, alpha m beta 2) on human neutrophils. J Exp Med 1991 Jun 1;173:1493–500. Cross Ref link Pubmed link , , , et al.
- 88 Differences between human eosinophils and neutrophils in the function and expression of sialic acid‐containing counterligands for E‐selectin. J Immunol 1994 Jan 15;152:774–82. Pubmed link , , , , , .
- 89 Effect of in vivo interleukin‐1 on adhesion molecule expression in normal human skin. J Invest Dermatol 1992 Mar;98:384–7. Cross Ref link Pubmed link , , , , , .
- 90 A unique phenotype of skin‐associated lymphocytes in humans. Preferential expression of the HECA‐452 epitope by benign and malignant T cells at cutaneous sites. Am J Pathol 1990 May;136:1053–68. Pubmed link , , , .
- 91 Control of lymphocyte recirculation in man. II. Differential regulation of the cutaneous lymphocyte‐associated antigen, a tissue‐selective homing receptor for skin‐homing T cells. J Immunol 1993 Feb 1;150:1122–36. Pubmed link , , , , , .
- 92 Cutaneous lymphocyte antigen is a specialized form of PSGL‐1 expressed on skin‐homing T cells. Nature 1997 Oct 30;389:978–81. Cross Ref link Pubmed link , , , .
- 93 Anti‐E‐selectin is ineffective in the treatment of psoriasis: a randomized trial. Br J Dermatol 2002 May;146:824–31. Cross Ref link Pubmed link , , , et al.
- 94 Serum ELAM‐1 is increased in vasculitis, scleroderma, and systemic lupus erythematosus. J Rheumatol 1993 May;20:809–14. Pubmed link , , , , .
- 95 Soluble E‐selectin serum levels correlate with disease activity in psoriatic patients. Clin Exp Dermatol 1999 Jan;24:33–6. Cross Ref link Pubmed link , , , , .
- 96 Soluble E‐selectin as a marker of disease activity in pustulosis palmaris et plantaris. Acta Derm Venereol 1999 Nov;79:462–4. Cross Ref link Pubmed link , , , , .
- 97 A cell‐surface molecule involved in organ‐specific homing of lymphocytes. Nature 1983 Jul 7–13;304:30–4. Cross Ref link Pubmed link , , .
- 98 Rapid modulation of homing receptors (gp90MEL‐14) induced by activators of protein kinase C. Receptor shedding due to accelerated proteolytic cleavage at the cell surface. J Immunol 1990 Apr 15;144:3130–6. Pubmed link , .
- 99 Sequential contribution of L‐ and P‐selectin to leukocyte rolling in vivo. J Exp Med 1995 Feb 1;181:669–75. Cross Ref link Pubmed link , , , et al.
- 100 The L‐selectin antibody FMC46 mediates rapid, transient increase in intracellular calcium in human peripheral blood mononuclear cells and Daudi lymphoma cells. Biochem Biophys Res Commun 1995 Dec 26;217:1145–50. Cross Ref link Pubmed link , , .
- 101 Ligation of L‐selectin on T lymphocytes activates beta1 integrins and promotes adhesion to fibronectin. J Immunol 1997 Oct 1;159:3498–507. Pubmed link , , , .
- 102 GlyCAM‐1, a physiologic ligand for L‐selectin, activates beta 2 integrins on naive peripheral lymphocytes. J Exp Med 1996 Oct 1;184:1343–8. Cross Ref link Pubmed link , , , et al.
- 103 Signaling functions of L‐selectin. Enhancement of tyrosine phosphorylation and activation of MAP kinase. J Biol Chem 1995 Jun 23;270:15403–11. Cross Ref link Pubmed link , , , , .
- 104 Targeting selectins and selectin ligands in inflammation and cancer. Expert Opin Ther Targets 2007 Nov;11:1473–91. Cross Ref link Pubmed link , , , .
- 105 Selective requirements for leukocyte adhesion molecules in models of acute and chronic cutaneous inflammation: participation of E‐ and P‐ but not L‐selectin. Blood 1999 Jan 15;93:580–9. Pubmed link , , .
- 106 PSGL‐1 as a novel therapeutic target. Drug News Perspect 2004 Nov;17:579–86. Cross Ref link Pubmed link .
- 107 Anti‐selectin therapy for the treatment of inflammatory diseases. Inflamm Allergy Drug Targets 2008 Jun;7:85–93. Cross Ref link Pubmed link , .
- 108 Diminished lymphocyte adhesion and alleviation of allergic responses by small‐molecule‐ or antibody‐mediated inhibition of L‐selectin functions. J Invest Dermatol 2007 Jan;127:90–7. Cross Ref link Pubmed link , , , et al.
- 109 PS3, a semisynthetic beta‐1,3‐glucan sulfate, diminishes contact hypersensitivity responses through inhibition of L‐ and P‐selectin functions. J Invest Dermatol 2009 May;129:1192–202. Cross Ref link Pubmed link , , , et al.
Endothelial adhesion molecules regulating leukocyte migration
- 110 Cytokines and chemokines orchestrate atopic skin inflammation. J Allergy Clin Immunol 2006 Jul;118:178–89. Cross Ref link Pubmed link , , , .
- 111 Integrins: a family of cell surface receptors. Cell 1987 Feb 27;48:549–54. Cross Ref link Pubmed link .
Cell–cell adhesion in the epidermis and dermis during inflammation
- 112 Integrins: a family of cell surface receptors. Cell 1987 Feb 27;48:549–54. Cross Ref link Pubmed link .
- 113 Integrins: bidirectional, allosteric signaling machines. Cell 2002 Sep 20;110:673–87. Cross Ref link Pubmed link .
- 114 Novel function for beta 1 integrins in keratinocyte cell–cell interactions. J Cell Biol 1990 Mar;110:803–15. Cross Ref link Pubmed link , , , et al.
- 115 Modulating leukocyte recruitment in inflammation. J Allergy Clin Immunol 20–07 Jul;120:3–10. Cross Ref link Pubmed link , , .
- 116 Radiographic evidence of cholecystokinin octapeptide receptors in the hamster gallbladder. Scand J Gastroenterol 1991 Nov;26:1165–72. Cross Ref link Pubmed link , , , et al.
- 117 Induction of organ‐selective CD4+ regulatory T cell homing. Eur J Immunol 2007 Apr;37:978–89. Cross Ref link Pubmed link , , , et al.
- 118 Inhibition of eosinophilia in vivo by a small molecule inhibitor of very late antigen (VLA)‐4. Eur J Pharmacol 2007 Mar 22;559:202–9. Cross Ref link Pubmed link , , , et al.
- 119 Activated macrophages are essential in a murine model for T cell‐mediated chronic psoriasiform skin inflammation. J Clin Invest 2006 Aug;116:2105–14. Cross Ref link Pubmed link , , , et al.
- 120 Clinical utility of tryptase levels in systemic mastocytosis and associated hematologic disorders. Leuk Res 2001 Jul;25:553–62. Cross Ref link Pubmed link .
- 121 In vivo functions of integrins: lessons from null mutations in mice. Matrix Biol 2000 Jul;19:203–9. Cross Ref link Pubmed link .
- 122 The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell–cell and cell–substrate adhesion of human epidermal cells. J Cell Biol 1990 Apr;110:1387–404. Cross Ref link Pubmed link , , , .
- 123 The alpha 6 beta 1 (VLA‐6) and alpha 6 beta 4 protein complexes: tissue distribution and biochemical properties. J Cell Sci 1990 Jun;96(Pt 2):207–17. Pubmed link , , , .
- 124 Expression of beta 1, beta 3, beta 4, and beta 5 integrins by human epidermal keratinocytes and non‐differentiating keratinocytes. J Cell Biol 1991 Nov;115:829–41. Cross Ref link Pubmed link , .
- 125 Changes in keratinocyte adhesion during terminal differentiation: reduction in fibronectin binding precedes alpha 5 beta 1 integrin loss from the cell surface. Cell 1990 Oct 19;63:425–35. Cross Ref link Pubmed link , .
- 126 Decreased expression of fibronectin and the alpha 5 beta 1 integrin during terminal differentiation of human keratinocytes. J Cell Sci 1991 Feb;98(Pt 2):225–32. Pubmed link , .
- 127 Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis. J Clin Invest 1992 Jun;89:1892–901. Cross Ref link Pubmed link , , , .
- 128 Expression of beta 4 integrins in human skin: comparison of epidermal distribution with beta 1‐integrin epitopes, and modulation by calcium and vitamin D3 in cultured keratinocytes. J Invest Dermatol 1991 Sep;97:562–7. Cross Ref link Pubmed link , , , , .
- 129 Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes. Proc Natl Acad Sci U S A 1990 Nov;87:8970–4. Cross Ref link Pubmed link , , , , .
- 130 Overexpression of extracellular matrix receptors (VLA‐3, 5 and 6) on psoriatic keratinocytes. Br J Dermatol 1991 Sep;125:211–16. Cross Ref link Pubmed link , , .
- 131 Regulation of extracellular matrix proteins and integrin cell substratum adhesion receptors on epithelium during cutaneous human wound healing in vivo. Am J Pathol 1993 Nov;143:1458–69. Pubmed link , , , , .
- 132 Distinctive integrin expression in the newly forming epidermis during wound healing in humans. J Invest Dermatol 1993 Oct;101:600–4. Cross Ref link Pubmed link , , , , , .
- 133 Keratinocytes in human wounds express alpha v beta 6 integrin. J Invest Dermatol 1996 Jan;106:42–8. Cross Ref link Pubmed link , , , et al.
- 134 Human Thy‐1 induces secretion of matrix metalloproteinase‐9 and CXCL8 from human neutrophils. Eur J Immunol 2008 May;38:1391–403. Cross Ref link Pubmed link , , , , .
- 135 Efalizumab, a reversible T‐cell modulator for psoriasis. J Cutan Med Surg 2006;9 Suppl. 1:4–9. Cross Ref link Pubmed link , , .
- 136 1‐alpha,25‐Dihydroxyvitamin D3 modulates the response of human keratinocytes to ionizing radiation exposure. Anticancer Res 2006 Jul–Aug;26:2735–41. Pubmed link , , , .
- 137 Sharpin is a keg regulator of immune and inflammatory responses. J Cell Mol Med 2012 Oct;16(10):2271–9. Cross Ref link Pubmed link , , , .
Leukocyte trafficking and integrins
- 138 Regulatory mechanisms in leukocyte adhesion: flexible receptors for sophisticated travelers. Immunol Today 1992 Jun;13:224–30. Cross Ref link Pubmed link , , .
- 139 Ins and outs of LFA‐1. Immunol Today 1995 Oct;16:479–83. Cross Ref link Pubmed link , , .
- 140 Activation of LFA‐1 through a Ca2(+)‐dependent epitope stimulates lymphocyte adhesion. J Cell Biol 1991 Jan;112:345–54. Cross Ref link Pubmed link , , , et al.
- 141 Adhesive signaling in platelets. Curr Opin Cell Biol 1994 Oct;6:695–704. Cross Ref link Pubmed link , , .
- 142 Extracellular Ca2+ modulates leukocyte function‐associated antigen‐1 cell surface distribution on T lymphocytes and consequently affects cell adhesion. J Cell Biol 1994 Mar;124:1061–70. Cross Ref link Pubmed link , , , .
- 143 Efalizumab for patients with moderate to severe plaque psoriasis: a randomized controlled trial. JAMA 2003 Dec 17;290:3073–80. Cross Ref link Pubmed link , , , et al.
Cell adhesion molceules of the immunoglobulin superfamily
- 144 A human intercellular adhesion molecule (ICAM‐1) distinct from LFA‐1. J Immunol 1986 Aug 15;137:1270–4. Pubmed link , , , .
- 145 Intercellular adhesion molecule 3, a third adhesion counter‐receptor for lymphocyte function‐associated molecule 1 on resting lymphocytes. J Exp Med 1992 Jan 1;175:185–90. Cross Ref link Pubmed link , .
- 146 Cooperative interactions of LFA‐1 and Mac‐1 with intercellular adhesion molecule‐1 in facilitating adherence and transendothelial migration of human neutrophils in vitro. J Clin Invest 1989 Jun;83:2008–17. Cross Ref link Pubmed link , , , , .
- 147 PECAM‐1 is required for transendothelial migration of leukocytes. J Exp Med 1993 Aug 1;178:449–60. Cross Ref link Pubmed link , , , .
- 148 Circulating adhesion molecules in disease. Immunol Today 1993 Oct;14:506–12. Cross Ref link Pubmed link , .
- 149 Soluble E‐selectin, other markers of inflammation and disease severity in children with atopic dermatitis. Br J Dermatol 1998 Mar;138:431–5. Cross Ref link Pubmed link , , , et al.
- 150 Soluble intercellular adhesion molecule‐1 and soluble E‐selectin levels in patients with atopic dermatitis. Br J Dermatol 1996 Apr;134:657–61. Cross Ref link Pubmed link , , , et al.
- 151 Squamous cell carcinoma‐related antigen (SCCr‐Ag), sICAM‐1 and beta 2‐microglobulin are useful markers of disease activity in psoriasis. Acta Derm Venereol 1999 Mar;79:132–5. Cross Ref link Pubmed link , , , , , .
- 152 Elevated levels of circulating intercellular adhesion molecule‐3 (cICAM‐3) in psoriasis. Acta Derm Venereol 1996 Jan;76:2–5. Pubmed link , , , .
- 153 Serum adhesion molecules and interleukin‐2 receptor as markers of tumour load and prognosis in advanced cutaneous melanoma. Eur J Cancer 2001 Sep;37:1629–34. Cross Ref link Pubmed link , , , et al.
- 154 Circulating soluble adhesion molecules in patients with systemic sclerosis: correlation between circulating soluble vascular cell adhesion molecule‐1 (sVCAM‐1) and impaired left ventricular diastolic function. Rheumatol Int 2000 Dec;20:21–4. Cross Ref link Pubmed link , , , et al.
- 155 Increased serum levels of soluble vascular cell adhesion molecule 1 and E‐selectin in patients with localized scleroderma. J Am Acad Dermatol 2000 Jan;42:64–9. Cross Ref link Pubmed link , , , et al.
- 156 L1 cell adhesion molecule (L1CAM) in invasive tumors. Cancer Lett 2009 Sep 18;282(2):137–45. Cross Ref link Pubmed link , , .
- 157 Molecular isolation and characterization of a soluble isoform of activated leukocyte cell adhesion molecule that modulates endothelial cell function. J Biol Chem 2004 Dec 31;279:55315–23. Cross Ref link Pubmed link , .
- 158 Mouse CD99 participates in T‐cell recruitment into inflamed skin. Blood 2004 Nov 15;104:3205–13. Cross Ref link Pubmed link , , , , , .
Adhesion molecules on activated keratinocytes
- 159 Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM‐1). J Exp Med 1988 Apr 1;167:1323–40. Cross Ref link Pubmed link , , , .
- 160 Gamma interferon induces different keratinocyte cellular patterns of expression of HLA‐DR and DQ and intercellular adhesion molecule‐I (ICAM‐I) antigens. Br J Dermatol 1989 Jan;120:1–8. Cross Ref link Pubmed link , , .
- 161 Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. J Immunol 1986 Sep 15;137:1893–6. Pubmed link , , , et al.
- 162 Kinetics and characterization of intercellular adhesion molecule‐1 (ICAM‐1) expression on keratinocytes in various inflammatory skin lesions and malignant cutaneous lymphomas. J Am Acad Dermatol 1989 May;20:782–90. Cross Ref link Pubmed link , , , , , .
- 163 Induction by IL 1 and interferon‐gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM‐1). J Immunol 1986 Jul 1;137:245–54. Pubmed link , , , , .
- 164 Points of control exerted along the macrophage–endothelial cell‐polymorphonuclear neutrophil axis by PECAM‐1 in the innate immune response of acute colonic inflammation. J Immunol 2008 Aug 1;181:2145–54. Cross Ref link Pubmed link , , , et al.
- 165 Stress‐induced neurogenic inflammation in murine skin skews dendritic cells towards maturation and migration: key role of intercellular adhesion molecule‐1/leukocyte function‐associated antigen interactions. Am J Pathol 2008 Nov;173:1379–88. Cross Ref link Pubmed link , , , , , .
- 166 Epstein–Barr virus‐encoded LMP1 induces a hyperproliferative and inflammatory gene expression programme in cultured keratinocytes. J Gen Virol 2008 Nov;89:2806–20. Cross Ref link Pubmed link , , , et al.
- 167 Keratinocytes resident in normal human skin constitutively express, at low levels, the intercellular adhesion molecule‐1. An in situ immunoelectronmicroscopy study. Br J Dermatol 1996 Jul;135:32–5. Cross Ref link Pubmed link , , , , , .
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- 176 Intercellular adhesion molecule‐I (ICAM‐I) expression correlated to inflammation. Br J Dermatol 1989 Apr;120:479–84. Cross Ref link Pubmed link , , , .
- 177 Increased expression of adhesion receptors in both lesional and non‐lesional psoriatic skin. Arch Dermatol Res 1994;286:304–11. Cross Ref link Pubmed link , , , , , .
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Endothelin 1
- 180 A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988 Mar 31;332:411–15. Cross Ref link Pubmed link , , , et al.
- 181 Cultured human keratinocytes synthesize and secrete endothelin‐1. J Invest Dermatol 1993 Jan;100:23–6. Cross Ref link Pubmed link , , , , , .
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- 184 Effects of endothelins on signal transduction and proliferation in human melanocytes. J Biol Chem 1991 Sep 25;266:18352–7. Pubmed link , , .
- 185 Inflammatory murine skin responses to UV‐B light are partially dependent on endothelin‐1 and mast cells. Am J Pathol 2006 Sep;169:815–22. Cross Ref link Pubmed link , , , .
- 186 Mast cells promote homeostasis by limiting endothelin‐1‐induced toxicity. Nature 2004 Nov 25;432:512–16. Cross Ref link Pubmed link , , , et al.
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Innate immune defence mechanisms
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- 195 Leukocyte granule proteins mobilize innate host defenses and adaptive immune responses. Immunol Rev 2000 Oct;177:68–78. Cross Ref link Pubmed link , , , .
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- 197 Cathelicidins – a family of multifunctional antimicrobial peptides. Cell Mol Life Sci 2003 Apr;60:711–20. Cross Ref link Pubmed link , .
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- 199 Antimicrobial peptides in health and disease. N Engl J Med 2002 Oct 10;347:1199–200. Cross Ref link Pubmed link .
- 200 A peptide antibiotic from human skin. Nature 1997 Jun 26;387:861. Cross Ref link Pubmed link , , , .
- 201 Isolation and characterization of human beta‐defensin‐3, a novel human inducible peptide antibiotic. J Biol Chem 2001 Feb 23;276:5707–13. Cross Ref link Pubmed link , , , .
- 202 The expression of the gene coding for the antibacterial peptide LL‐37 is induced in human keratinocytes during inflammatory disorders. J Biol Chem 1997 Jun 13;272:15258–63. Cross Ref link Pubmed link , , , et al.
- 203 Differential regulation of beta‐defensin expression in human skin by microbial stimuli. J Immunol 2005 Apr 15;174:4870–9. Cross Ref link Pubmed link , , , , , .
- 204 Histamine enhances the production of human beta‐defensin‐2 in human keratinocytes. Am J Physiol Cell Physiol 2007 Dec;293:C1916–23. Cross Ref link Pubmed link , .
- 205 Antimicrobial peptides human beta‐defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines. J Invest Dermatol 2007 Mar;127:594–604. Cross Ref link Pubmed link , , , et al.
- 206 Barrier function, epidermal differentiation, and human beta‐defensin 2 expression in tinea corporis. J Invest Dermatol 2007 Jul;127:1720–7. Cross Ref link Pubmed link , , , et al.
- 207 The constitutive capacity of human keratinocytes to kill Staphylococcus aureus is dependent on beta‐defensin 3. J Invest Dermatol 2007 Oct;127:2368–80. Cross Ref link Pubmed link , , , , , .
- 208 Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. Nat Med 2007 Aug;13:975–80. Cross Ref link Pubmed link , , , et al.
- 209 Histatins, a novel family of histidine‐rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans. J Biol Chem 1988 Jun 5;263:7472–7. Pubmed link , , , et al.
- 210 Antiviral effect of human saliva against hantavirus. J Med Virol 2008 Dec;80:2122–6. Cross Ref link Pubmed link , , , , , .
- 211 Histatins are the major wound‐closure stimulating factors in human saliva as identified in a cell culture assay. FASEB J 2008 Nov;22:3805–12. Cross Ref link Pubmed link , , , et al.
- 212 Safety and clinical effects of topical histatin gels in humans with experimental gingivitis. J Clin Periodontol 2002 Dec;29:1051–8. Cross Ref link Pubmed link , , , , .
- 213 Histatin 5 initiates osmotic stress response in Candida albicans via activation of the Hog1 mitogen‐activated protein kinase pathway. Eukaryot Cell 2007 Oct;6:1876–88. Cross Ref link Pubmed link , , , , .
- 214 The human cathelicidin LL‐37 host defense peptide upregulates tight junction‐related proteins and increases human epidermal keratinocyte barrier function. J Innate Immun 2014 May 23. Pubmed link , , , et al.
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- 216 Neurovascular and neuroimmune aspects in the pathophysiology of rosacea. J Investig Dermatol Symp Proc 2011 Dec;15(1): 53–62. Cross Ref link Pubmed link , , , et al.
- 217 Defensins – innate immunity at the epithelial frontier. Eur J Gastroenterol Hepatol 2001 Jul;13:771–6. Cross Ref link Pubmed link , .
- 218 The IAP family: endogenous caspase inhibitors with multiple biological activities. Cell Res 2000 Sep;10:169–77. Cross Ref link Pubmed link , .
- 219 Leukocyte antimicrobial peptides: multifunctional effector molecules of innate immunity. J Leukoc Biol 2000 Dec;68:785–92. Pubmed link .
- 220 Beta‐defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science 1999 Oct 15;286:525–8. Cross Ref link Pubmed link , , , et al.
- 221 By IL‐1 signaling, monocyte‐derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide. J Immunol 2003 Jan 1;170:575–80. Cross Ref link Pubmed link , , .
- 222 Mechanisms for induction of acquired host immunity by neutrophil peptide defensins. Proc Natl Acad Sci U S A 1999 Jan 19;96:651–6. Cross Ref link Pubmed link , , , , .
- 223 Antimicrobial peptides in the skin. N Engl J Med 2003 Jan 23;348:361–3;author reply, 3. Cross Ref link Pubmed link , , .
- 224 Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes. Infect Immun 1987 Mar;55:568–71. Pubmed link .
- 225 Inhibition of activation of the classical pathway of complement by human neutrophil defensins. Blood 1998 Nov 15;92:3898–903. Pubmed link , , , , .
- 226 Cutting edge: mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide. J Immunol 2003 Mar 1;170:2274–8. Cross Ref link Pubmed link , , .
- 227 Human beta defensin‐1 and ‐2 expression in human pilosebaceous units: upregulation in acne vulgaris lesions. J Invest Dermatol 2001 Nov;117:1120–5. Cross Ref link Pubmed link , , , et al.
- 228 Localization of human beta‐defensin‐2 and human neutrophil peptides in superficial folliculitis. Br J Dermatol 2003 Jan;148:188–91. Cross Ref link Pubmed link , , , , .
- 229 Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med 2002 Oct 10;347:1151–60. Cross Ref link Pubmed link , , , et al.
- 230 Inflammatory cytokines break down intrinsic immunological tolerance of human primary keratinocytes to cytosolic DNA. J Immunol 2014 Mar 1;192(5):2395–404. Cross Ref link Pubmed link , , , et al.
- 231 The newborn infant is protected by an innate antimicrobial barrier: peptide antibiotics are present in the skin and vernix caseosa. Br J Dermatol 2002 Dec;147:1127–34. Cross Ref link Pubmed link , , , et al.
- 232 Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors. J Immunol 2003 Jun 1;170:5583–9. Cross Ref link Pubmed link , , , , , .
- 233 Effects of human neutrophil peptide‐1 on the expression of interstitial collagenase and type I collagen in human dermal fibroblasts. Arch Dermatol Res 2002 Jul;294:185–9. Cross Ref link Pubmed link , , , , .
- 234 Highly complex peptide aggregates of the S100 fused‐type protein hornerin are present in human skin. J Invest Dermatol 2009 Jun;129(6):1446–58. Cross Ref link Pubmed link , , , et al.
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- 236 Hornerin is a component of the epidermal cornified cell envelopes. FASEB J 2011 May;25(5):1567–76. Cross Ref link Pubmed link , , , et al.
- 237 Defects of filaggrin‐like proteins in both lesional and nonlesional atopic skin. J Allergy Clin Immunol 2013 Apr;131(4):1094–102. Cross Ref link Pubmed link , , , et al.
Toll‐like receptors, Nucleotide binding site and leucine‐rich repeat proteins, Scavenger receptors, Mannose receptor and other C‐type lectins
- 238 Antibodies to proteinase 3 prime human oral, lung, and kidney epithelial cells to secrete proinflammatory cytokines upon stimulation with agonists to various Toll‐like receptors, NOD1, and NOD2. Clin Vaccine Immunol 2008 Jul;15:1060–6. Cross Ref link Pubmed link , , .
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- 242 Mrp8 and Mrp14 are endogenous activators of Toll‐like receptor 4, promoting lethal, endotoxin‐induced shock. Nat Med 2007 Sep;13:1042–9. Cross Ref link Pubmed link , , , et al.
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- 245 TIRAP: an adapter molecule in the Toll signaling pathway. Nat Immunol 2001 Sep;2:835–41. Cross Ref link Pubmed link , , .
- 246 Genetic approaches to the study of Toll‐like receptor function. Microbes Infect 2002 Jul;4:887–95. Cross Ref link Pubmed link , .
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- 249 Toll‐like receptor and IL‐12 signaling control susceptibility to contact hypersensitivity. J Exp Med 2008 Sep 1;205: 2151–62. Cross Ref link Pubmed link , , , et al.
- 250 Glucocorticoids enhance Toll‐like receptor 2 expression in human keratinocytes stimulated with Propionibacterium acnes or proinflammatory cytokines. J Invest Dermatol 2009 Feb;129:375–82. Cross Ref link Pubmed link , , , , , .
- 251 Double‐stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3‐, PKR‐, and MDA5/RIG‐I‐mediated differential signaling. J Immunol 2008 Aug 15;181:2694–704. Cross Ref link Pubmed link , , , et al.
- 252 Nods, Nalps and Naip: intracellular regulators of bacterial‐induced inflammation. Cell Microbiol 2003 Sep;5:581–92. Cross Ref link Pubmed link , , , .
- 253 NODs: intracellular proteins involved in inflammation and apoptosis. Nat Rev Immunol 2003 May;3:371–82. Cross Ref link Pubmed link , .
- 254 Scavenger receptors in innate immunity. Curr Opin Immunol 2002 Feb;14:123–8. Cross Ref link Pubmed link , , .
- 255 SCART scavenger receptors identify a novel subset of adult gammadelta T cells. J Immunol 2008 Aug 1;181:1710–16. Cross Ref link Pubmed link , , .
- 256 Expression of CD163 in dermatofibroma, cellular fibrous histiocytoma, and dermatofibrosarcoma protuberans: comparison with CD68, CD34, and Factor XIIIa. J Cutan Pathol 2006 May;33:353–60. Cross Ref link Pubmed link , .
- 257 The mannose receptor family. Biochim Biophys Acta 2002 Sep 19;1572:364–86. Cross Ref link Pubmed link , .
- 258 Mannose receptor‐mediated regulation of serum glycoprotein homeostasis. Science 2002 Mar 8;295:1898–901. Cross Ref link Pubmed link , , , et al.
- 259 Dermal dendritic cells” comprise two distinct populations: CD1+ dendritic cells and CD209+ macrophages. J Invest Dermatol 2008 Sep;128:2225–31. Cross Ref link Pubmed link , , , , . “
- 260 Dendritic cell interaction with Candida albicans critically depends on N‐linked mannan. J Biol Chem 2008 Jul 18;283:20590–9. Cross Ref link Pubmed link , , , et al.
- 261 Macrophage mannose receptor on lymphatics controls cell trafficking. Blood 2008 Jul 1;112:64–72. Cross Ref link Pubmed link , , , et al.
- 262 Enhanced anti‐inflammation of inhaled dexamethasone palmitate using mannosylated liposomes in an endotoxin‐induced lung inflammation model. Mol Pharmacol 2008 Nov;74:1183–92. Cross Ref link Pubmed link , , , , , .
Cells regulating innate immunity
Natural killer cells
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- 279 Activation and function of natural killer cell responses during viral infections. Curr Opin Immunol 1997 Feb;9:24–34. Cross Ref link Pubmed link .
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Polymorphonuclear granulocytes
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- 296 Staphylococcal cutaneous infections: invasion, evasion and aggression. J Dermatol Sci 2006 Jun;42:203–14. Cross Ref link Pubmed link , , , .
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Mast cells
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- 345 Variable expression of activation‐linked surface antigens on human mast cells in health and disease. Immunol Rev 2001 Feb;179:74–81. Cross Ref link Pubmed link , , , et al.
- 346 Characterization of neuropeptide‐induced histamine release from human dispersed skin mast cells. Br J Pharmacol 1988 Sep;95:121–30. Cross Ref link Pubmed link , , .
- 347 Heterogeneity of human mast cells and basophils in response to muscle relaxants. Anesthesiology 1991 Jun;74:1078–86. Cross Ref link Pubmed link , , , , , .
- 348 Histamine is released in the wheal but not the flare following challenge of human skin in vivo: a microdialysis study. Clin Exp Allergy 1997 Mar;27:284–95. Cross Ref link Pubmed link , , .
- 349 Recurrent urticaria and reduced diamine oxidase activity. Clin Exp Allergy 1990 Jul;20:373–6. Cross Ref link Pubmed link , , , , .
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- 351 Variant LTC(4) synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast. Thorax 2000 Oct;55 Suppl. 2:S28–31. Cross Ref link Pubmed link , , , et al.
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- 356 Proteinase‐activated receptor‐2 mediates itch: a novel pathway for pruritus in human skin. J Neurosci 2003 Jul 16;23:6176–80. Pubmed link , , , et al.
- 357 Agonists of proteinase‐activated receptor 2 induce inflammation by a neurogenic mechanism. Nat Med 2000 Feb;6:151–8. Cross Ref link Pubmed link , , , et al.
- 358 Identification of a potential effector function for IgE autoantibodies in the organ‐specific autoimmune disease bullous pemphigoid. J Invest Dermatol 2003 May;120:784–8. Cross Ref link Pubmed link , , , et al.
- 359 Gene polymorphism in Netherton and common atopic disease. Nat Genet 2001 Oct;29:175–8. Cross Ref link Pubmed link , , , et al.
- 360 NF‐kappa B and TNF‐alpha: a positive autocrine loop in human lung mast cells? J Immunol 2002 Nov 1;169:5287–93. Cross Ref link Pubmed link , , , , , .
- 361 Human lung mast cells are enriched in the capacity to produce granulocyte–macrophage colony‐stimulating factor in response to IgE‐dependent stimulation. Eur J Immunol 1998 Feb;28:708–15. Cross Ref link Pubmed link , , , et al.
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- 363 Production of IL‐13 by human lung mast cells in response to Fcepsilon receptor cross‐linkage. Clin Exp Allergy 1998 Oct;28:1219–27. Cross Ref link Pubmed link , , , , , .
- 364 Immunology of cutaneous leishmaniasis: the role of mast cells, phagocytes and dendritic cells for protective immunity. Eur J Dermatol 2007 Mar–Apr;17:115–22. Pubmed link .
- 365 Histamine upregulates keratinocyte MMP‐9 production via the histamine H1 receptor. J Invest Dermatol 2008 Dec;128:2783–91. Cross Ref link Pubmed link , , , et al.
- 366 Mast cells: versatile regulators of inflammation, tissue remodeling, host defense and homeostasis. J Dermatol Sci 2008 Jan;49:7–19. Cross Ref link Pubmed link , .
- 367 Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nat Rev Immunol 2008 Jun;8:478–86. Cross Ref link Pubmed link , , .
- 368 Mast cells in the promotion and limitation of chronic inflammation. Immunol Rev 2007 Jun;217:304–28. Cross Ref link Pubmed link , , , , , .
Monocytes and macrophages
- 369 Immunobiology, 5 edn. New York: Taylor & Francis Inc., 2001. , , , .
- 370 Macrophages. New York: Garland, 2001. , , .
- 371 Endotoxin and muramyl dipeptide modulate surface receptor expression on human mononuclear cells. Immunopharmacology 2000 Jul 20;48:117–28. Cross Ref link Pubmed link , , , , .
- 372 Protease‐activated receptors: novel PARtners in innate immunity. Trends Immunol 2007 Dec;28:541–50. Cross Ref link Pubmed link , , , .
- 373 Ultraviolet B radiation upregulates the production of macrophage migration inhibitory factor (MIF) in human epidermal keratinocytes. J Invest Dermatol 1999 Feb;112:210–15. Cross Ref link Pubmed link , , , .
- 374 Ultraviolet A‐induced production of matrix metalloproteinase‐1 is mediated by macrophage migration inhibitory factor (MIF) in human dermal fibroblasts. J Biol Chem 2004 Jan 16;279:1676–83. Cross Ref link Pubmed link , , , et al.
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- 376 Impaired contact hypersensitivity in macrophage migration inhibitory factor‐deficient mice. Eur J Immunol 2003 Jun;33:1478–87. Cross Ref link Pubmed link , , , et al.
- 377 Macrophage migration inhibitory factor is an essential immunoregulatory cytokine in atopic dermatitis. Biochem Biophys Res Commun 1997 Nov 7;240:173–8. Cross Ref link Pubmed link , , , , .
- 378 Histochemical analysis of macrophage migration inhibitory factor in psoriasis vulgaris. Histochem Cell Biol 2002 Sep;118:251–7. Pubmed link , , , et al.
- 379 Evidence for a role of macrophage migration inhibitory factor in psoriatic skin disease. Br J Dermatol 1999 Dec;141:1061–6. Cross Ref link Pubmed link , , , , , .
- 380 Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor. J Clin Invest 2003 May;111:1309–18. Cross Ref link Pubmed link , , , et al.
- 381 Expression of macrophage migration inhibitory factor in diffuse systemic sclerosis. Ann Rheum Dis 2003 May;62:460–4. Cross Ref link Pubmed link , , , et al.
- 382 Macrophage migratory inhibitory factor (MIF) expression in acute graft‐versus‐host disease (GVHD) in allogeneic hemopoietic stem cell transplant recipients. Bone Marrow Transplant 2002 Sep;30:375–80. Cross Ref link Pubmed link , , , et al.
- 383 Macrophage migration inhibitory factor. Crit Care Med 2002 Jan;30:S27–S35. Cross Ref link , .
- 384 Macrophage migration inhibitory factor: a regulator of innate immunity. Nat Rev Immunol 2003 Oct;3:791–800. Cross Ref link Pubmed link , .
- 385 Macrophage activation through CCR5‐ and CXCR4‐mediated gp120‐elicited signaling pathways. J Leukoc Biol 2003 Nov;74:676–82. Cross Ref link Pubmed link , , , , , .
- 386 Peroxisome proliferator‐activated receptors and the control of inflammation. Curr Drug Targets Inflamm Allergy 2002 Sep;1:243–8. Cross Ref link Pubmed link , , .
- 387 Impaired skin wound healing in peroxisome proliferator‐activated receptor (PPAR)alpha and PPARbeta mutant mice. J Cell Biol 2001;154:799–814. Cross Ref link Pubmed link , , , et al.
- 388 Expression of peroxisome proliferator‐activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes. J Invest Dermatol 2003 Sep;121:441–7. Cross Ref link Pubmed link , , , , .
- 389 The anti‐apoptotic role of PPARbeta contributes to efficient skin wound healing. J Steroid Biochem Mol Biol 2003 Jun;85:257–65. Cross Ref link Pubmed link , , , , .
- 390 Peroxisome proliferator‐activated receptors in cutaneous biology. Br J Dermatol 2003 Aug;149:229–36. Cross Ref link Pubmed link , .
- 391 Modulation of vascular inflammation by PPARs. Drug News Perspect 2003 Mar;16:109–16. Cross Ref link Pubmed link , , .
- 392 TREMs in the immune system and beyond. Nat Rev Immunol 2003 Jun;3:445–53. Cross Ref link Pubmed link .
- 393 iC3b arrests monocytic cell differentiation into CD1c‐expressing dendritic cell precursors: a mechanism for transiently decreased dendritic cells in vivo after human skin injury by ultraviolet B. J Invest Dermatol 2003 May;120:802–9. Cross Ref link Pubmed link , , , , , .
- 394 Cytokine signaling modules in inflammatory responses. Immunity 2008 Apr;28:477–87. Cross Ref link Pubmed link , .
- 395 Misbehaving macrophages in the pathogenesis of psoriasis. J Clin Invest 2006 Aug;116:2084–7. Cross Ref link Pubmed link , .
- 396 Targeting leukocyte recruitment in the treatment of psoriasis. Clin Dermatol 2008 Sep–Oct;26:527–38. Cross Ref link Pubmed link , , .
- 397 Immunopathogenesis of psoriasis. Clin Rev Allergy Immunol 2007 Oct;33:45–56. Cross Ref link Pubmed link , , .
- 398 Pathogenic role for skin macrophages in a mouse model of keratinocyte‐induced psoriasis‐like skin inflammation. J Clin Invest 2006 Aug;116:2094–104. Cross Ref link Pubmed link , , , et al.
- 399 Activated macrophages are essential in a murine model for T cell‐mediated chronic psoriasiform skin inflammation. J Clin Invest 2006 Aug;116:2105–14. Cross Ref link Pubmed link , , , et al.
- 400 Immunological profile of peripheral blood lymphocytes and monocytes/macrophages in Kawasaki disease. Clin Exp Immunol 2005 Sep;141:381–7. Cross Ref link Pubmed link , , .
- 401 Clearance of apoptotic cells in human SLE. Curr Dir Autoimmun 2006;9:173–87. Pubmed link , , , et al.
- 402 Alternative activation of macrophages. Nat Rev Immunol 2003 Jan;3(1):23–35. Cross Ref link Pubmed link .
Platelets
- 403 Study of platelet behavior in vivo after endothelial stimulation with laser irradiation using fluorescence intravital videomicroscopy and PEGylated liposome staining. Microvasc Res 2002 Sep;64:316–25. Cross Ref link Pubmed link , , , , .
- 404 Platelet involvement in cutaneous small vessel vasculitis. J Cutan Pathol 2002 Mar;29:176–80. Cross Ref link Pubmed link , , .
- 405 Platelets and inflammation. Anat Embryol (Berl) 1997 Jul;196:1–11. Cross Ref link Pubmed link .
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- 407 Signal transduction by the platelet Fc receptor. Blood 1990 Sep 15;76:1165–72. Pubmed link , .
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- 409 Human platelet activation by C3a and C3a des‐arg. J Exp Med 1983 Aug 1;158:603–15. Cross Ref link Pubmed link , .
- 410 Proteinase‐activated receptor‐2 in the skin: receptor expression, activation and function during health and disease. Drug News Perspect 2008 Sep;21:369–81. Cross Ref link Pubmed link , .
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- 412 versatility, modulation, and signaling in cell adhesion. Cell 1992 Apr 3;69:11–25. Cross Ref link Pubmed link . Integrins:
- 413 Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen. J Biol Chem 1991 Apr 25;266:7363–7. Pubmed link , , , , , .
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- 416 Biochemical mechanisms of platelet activation. Blood 1989 Sep;74:1181–95. Pubmed link , .
- 417 Platelet membrane responses to surface and suspension activation. Blood Cells 1990;16:43–70;discussion, 2. Pubmed link , , .
- 418 Platelet microparticles bind, activate and aggregate neutrophils in vitro. Blood Cells Mol Dis 1995;21:217–31;discussion, 31a. Cross Ref link Pubmed link , , , , .
- 419 Lipoxin formation in human platelets. Adv Prostaglandin Thromboxane Leukot Res 1991;21A:97–100. Pubmed link , , , .
- 420 Lipoxin and leukotriene production during receptor‐activated interactions between human platelets and cytokine‐primed neutrophils. Adv Prostaglandin Thromboxane Leukot Res 1991;21A:93–6. Pubmed link , , .
- 421 Basal transepidermal water loss is increased in platelet‐type 12‐lipoxygenase deficient mice. J Invest Dermatol 1999 Jun;112:861–5. Cross Ref link Pubmed link , , , , .
- 422 Human microvascular endothelial cells adhere to thrombospondin‐1 via an RGD/CSVTCG domain independent mechanism. J Invest Dermatol 1996 Feb;106:215–20. Cross Ref link Pubmed link , , , .
- 423 Increased and prolonged inflammation and angiogenesis in delayed‐type hypersensitivity reactions elicited in the skin of thrombospondin‐2‐deficient mice. Blood 2002 Jan 15;99:538–45. Cross Ref link Pubmed link , , , et al.
- 424 Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev 2004 Aug;15:255–73. Cross Ref link Pubmed link .
- 425 Proteinase‐activated receptors: transducers of proteinase‐mediated signaling in inflammation and immune response. Endocr Rev 2005 Feb;26:1–43. Cross Ref link Pubmed link , , , et al.
- 426 Activated, not resting, platelets increase leukocyte rolling in murine skin utilizing a distinct set of adhesion molecules. J Invest Dermatol 2004 Mar;122:830–6. Cross Ref link Pubmed link , , , et al.
- 427 The biology of P‐selectin glycoprotein ligand‐1: its role as a selectin counterreceptor in leukocyte‐endothelial and leukocyte‐platelet interaction. Thromb Haemost 1999 Jan;81:1–7. Pubmed link , , .
- 428 Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004 Jan;91:4–15. Pubmed link , , , , .
- 429 Inflammatory cells during wound repair: the good, the bad and the ugly. Trends Cell Biol 2005 Nov;15:599–607. Cross Ref link Pubmed link , .
- 430 Platelet function in cutaneous diseases. Platelets 2008 Aug;19:317–21. Cross Ref link Pubmed link , , .
- 431 Platelet‐mediated microvascular inflammation and thrombosis in thrombocythemia vera: a distinct aspirin‐responsive arterial thrombophilia, which transforms into a bleeding diathesis at increasing platelet counts. Pathol Biol (Paris) 2003 Apr;51:167–75. Cross Ref link Pubmed link .
Innate lymphoid cells
- 432 Th1‐ and Th2‐like subsets of innate lymphoid cells. Immunol Rev 2013 Mar;252(1):133–8. Cross Ref link Pubmed link , , .
- 433 TH2, allergy and group 2 innate lymphoid cells. Nat Immunol 2013 Jun;14(6):536–42. Cross Ref link Pubmed link , , , .
- 434 Beyond NK cells: the expanding universe of innate lymphoid cells. Front Immunol 2014 Jun 16;5:282. Cross Ref link Pubmed link , , .
- 435 The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nat Immunol 2011 Jan;12(1):21–7. Cross Ref link Pubmed link , .
- 436 A T‐bet gradient controls the fate and function of CCR6‐RORγt+ innate lymphoid cells. Nature 2013 Feb 14;494(7436):261–5. Cross Ref link Pubmed link , , , et al.
- 437 Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1. Nat Immunol 2013 Dec;14(12):1229–36. Cross Ref link Pubmed link , , , et al.
- 438 Regulation of cytokine secretion in human CD127(+) LTi‐like innate lymphoid cells by Toll‐like receptor 2. Immunity 2010 Nov 24;33(5):752–64. Cross Ref link Pubmed link , , , , , .
- 439 Characterization of innate lymphoid cells in human skin and blood demonstrates increase of NKp44 +ILC3 in psoriasis. J Invest Dermatol 2014 Apr;134(4):984–91. Cross Ref link Pubmed link , , , et al.
- 440 TSLP elicits IL‐33‐independent innate lymphoid cell responses to promote skin inflammation. Sci Transl Med 2013 Jan 30;5. , , , et al.
- 441 Increased number and frequency of group 3 innate lymphoid cells in nonlesional psoriatic skin. Br J Dermatol 2014 Mar;170(30):609–16. Cross Ref link Pubmed link , , , et al.
- 442 A role for IL‐25 and IL‐33‐driven type‐2 innate lymphoid cells in atopic dermatitis. J Exp Med 2013;210(13):2939–50. Cross Ref link Pubmed link , , , et al.
Adaptive immune system
Major histocompatibility complex and skin inflammation
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- 445 Allergen uptake and presentation by dendritic cells. Curr Opin Allergy Clin Immunol 2001 Feb;1:51–9. Cross Ref link Pubmed link .
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- 448 Cytotoxicity is mandatory for CD8(+) T cell‐mediated contact hypersensitivity. J Exp Med 1999 Mar 1;189:779–86. Cross Ref link Pubmed link , , , et al.
- 449 Studies of the modulation of MHC antigen and cell adhesion molecule expression on human dermal microvascular endothelial cells. J Invest Dermatol 1991 Aug;97:190–6. Cross Ref link Pubmed link , , , , .
- 450 Hyperkeratosis and leukocytosis in transgenic mice carrying MHC class I chain‐related gene B (MICB). Tissue Antigens 2003 Apr;61:300–7. Cross Ref link Pubmed link , , , et al.
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- 452 The major histocompatibility complex and inflammation. South Med J 2000 Feb;93:169–72. Cross Ref link Pubmed link , .
- 453 Oral treatment with recombinant human interleukin‐11 improves mucosal transport in the colon of human leukocyte antigen‐B27 transgenic rats. J Pharmacol Exp Ther 2004 Jan;308:206–13. Cross Ref link Pubmed link , , .
- 454 Expression of MHC class II, CD70, CD80, CD86 and pro‐inflammatory cytokines is differentially regulated in oral epithelial cells following bacterial challenge. Oral Microbiol Immunol 2003 Dec;18:350–8. Cross Ref link Pubmed link , , , , , .
- 455 HLA‐C expression pattern is spatially different between psoriasis and eczema skin lesions. J Invest Dermatol 2007 Feb;127:342–8. Cross Ref link Pubmed link , , , .
- 456 Fine mapping of the psoriasis susceptibility locus PSORS1 supports HLA‐C as the susceptibility gene in the Han Chinese population. PLOS Genet 2008 Mar;4:e1000038. Cross Ref link Pubmed link , , , et al.
- 457 Sequence and haplotype analysis supports HLA‐C as the psoriasis susceptibility 1 gene. Am J Hum Genet 2006 May;78:827–51. Cross Ref link Pubmed link , , , et al.
Antigen presentation
- 458 Differential and sequential expression of multiple chemokines during elicitation of allergic contact hypersensitivity. Am J Pathol 2001 Feb;158:431–40. Cross Ref link Pubmed link , , , , , .
- 459 Overexpression of CD1d by keratinocytes in psoriasis and CD1d‐dependent IFN‐gamma production by NK‐T cells. J Immunol 2000 Oct 1;165:4076–85. Cross Ref link Pubmed link , , , et al.
- 460 Hapten‐specific tolerance induced by acute, low‐dose ultraviolet B radiation of skin requires mast cell degranulation. Eur J Immunol 2001 Jun;31:1736–46. Cross Ref link Pubmed link , , , , .
- 461 Allergens and irritants transcriptionally upregulate CD80 gene expression in human keratinocytes. J Invest Dermatol 2000 Jun;114:1085–92. Cross Ref link Pubmed link , , , et al.
- 462 Immune response modifiers – mode of action. Exp Dermatol 2006 May;15(5):331–41. Cross Ref link Pubmed link , , , , .
- 463 Human beta‐defensin 3 induces maturation of human langerhans cell‐like dendritic cells: an antimicrobial peptide that functions as an endogenous adjuvant. J Invest Dermatol 2013 Feb;133(2):460–8. Cross Ref link Pubmed link , , , et al.
- 464 IL‐23 from langerhans cells is required for the development of imiquimod‐induced psoriasis‐like dermatitis by induction of IL‐17A‐producing γδ T cells. J Invest Dermatol 2014 Jul;134(7):1912–21. Cross Ref link Pubmed link , , , et al.
- 465 Imiquimod‐induced psoriasis‐like skin inflammation in mice is mediated via the IL‐23/IL‐17 axis. Immunology 2009 May 1;182(9):5836–45. Cross Ref link , , , et al.
- 466 Molecular mechanisms of lymphocyte‐mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu Rev Immunol 1996;14:207–32. Cross Ref link Pubmed link , , , , .
- 467 CD95 (Fas)‐dependent elimination of self‐reactive B cells upon interaction with CD4 +T cells. Nature 1995 Jul 13;376:181–4. Cross Ref link Pubmed link , , , et al.
- 468 Fas antigen is the major target molecule for CD4+ T cell‐mediated cytotoxicity. J Immunol 1994 Feb 1;152:1127–33. Pubmed link , , .
Acute‐phase proteins
- 469 Interactions of C‐reactive protein with the complement system. III. Complement‐dependent passive hemolysis initiated by CRP. J Exp Med 1975 Nov 1;142:1065–77. Cross Ref link Pubmed link , , , .
- 470 Features of human spontaneous vasculitis reproduced experimentally in animals. Effects of antiglobulins, C‐reactive protein and fibrin. Bayer Symposium. VI. Experimental Models of Chronic Inflammatory Disease. New York: Springer, 1977:117–51. Cross Ref link .
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- 472 Lack of mannose‐binding lectin‐A enhances survival in a mouse model of acute septic peritonitis. Microbes Infect 2002 Jul;4:773–84. Cross Ref link Pubmed link , , , et al.
- 473 Digestion of the fifth component of complement by leukocyte enzymes. Sequential generation of chemotactic activities for leukocytes and for tumor cells. Am J Pathol 1979 Jan;94:75–83. Pubmed link , , , , .
- 474 Role of proteinases in cutaneous inflammation. In: Safai B, Good RA, eds. Immunodermatology. New York: Plenum Press, 1981:177–87. Cross Ref link , , .
- 475 Clearance of apoptotic cells in human SLE. Curr Dir Autoimmun 2006;9:173–87. Pubmed link , , , et al.
- 476 Cutaneous reactions to recombinant cytokine therapy. J Am Acad Dermatol 1995 Sep;33:393–410;quiz, 2. Cross Ref link Pubmed link , .
Mediators of inflammation
Cytokines, Interleukins
- 477 Psoriatic skin lesions contain biologically active amounts of an interleukin 1‐like compound. J Immunol 1986 Dec 1;137:3469–74. Pubmed link , , , , , .
- 478 Cytokine signaling modules in inflammatory responses. Immunity 2008 Apr;28:477–87. Cross Ref link Pubmed link , .
- 479 T helper 1 to T helper 2 shift in cytokine expression: an autoregulatory process in superantigen‐associated psoriasis progression? J Med Microbiol 2009 Feb;58:180–4. Cross Ref link Pubmed link , , , , .
- 480 The majority of epidermal T cells in psoriasis vulgaris lesions can produce type 1 cytokines, interferon‐gamma, interleukin‐2, and tumor necrosis factor‐alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J Invest Dermatol 1999 Nov;113:752–9. Cross Ref link Pubmed link , , , , .
- 481 Antitumor activity of DAB389IL‐2 fusion toxin in mycosis fungoides. J Am Acad Dermatol 1998 Jul;39:63–73. Cross Ref link Pubmed link , , , et al.
- 482 Elevated levels of endogenous IL‐6 in systemic lupus erythematosus. A putative role in pathogenesis. J Immunol 1991 Jul 1;147:117–23. Pubmed link , , , , , .
- 483 Interleukin 6: insights to its function in skin by overexpression in transgenic mice. Proc Natl Acad Sci U S A 1992 Jun 1;89:5068–72. Cross Ref link Pubmed link , , , , .
- 484 Interleukin‐12 suppresses ultraviolet radiation‐induced apoptosis by inducing DNA repair. Nat Cell Biol 2002 Jan;4:26–31. Cross Ref link Pubmed link , , , et al.
- 485 T cells and mast cells as a major source of interleukin‐13 in atopic dermatitis. Dermatology 2002;205:11–17. Cross Ref link Pubmed link , , , , , .
- 486 Interleukin‐15 and the regulation of lymphoid homeostasis. Mol Immunol 2002 Dec;39:537–44. Cross Ref link Pubmed link , , , et al.
- 487 Inhibition of keratinocyte apoptosis by IL‐15: a new parameter in the pathogenesis of psoriasis? J Immunol 2000 Aug 15;165:2240–50. Cross Ref link Pubmed link , , , et al.
- 488 IL‐23 and T(H)17‐mediated inflammation in human allergic contact dermatitis. J Allergy Clin Immunol 2009 Feb;123:486–92. Cross Ref link Pubmed link , , , , .
- 489 Early growth response gene 2 (Egr‐2) controls the self‐tolerance of T cells and prevents the development of lupuslike autoimmune disease. J Exp Med 2008 Sep 29;205:2295–307. Cross Ref link Pubmed link , , , et al.
- 490 Keratinocytes in epidermal immune responses. Curr Opin Allergy Clin Immunol 2001 Oct;1:469–76. Cross Ref link Pubmed link , , .
- 491 Interleukin‐20 protien locates to distinct mononuclear cells in psoriatic skin. Exp Dermatol 2014;May 23(5):349–52. Cross Ref link Pubmed link , , , et al.
- 492 Interleukin‐20 plays a critical role in maintenance and development of psoriasis in human xenograft transplantation model. Br J Dermatol 2009 Feb;160(2):284–96. Cross Ref link Pubmed link , , , et al.
- 493 Interleukin‐21 and the IL‐21 receptor: novel effectors of NK and T cell responses. J Leukoc Biol 2002 Nov;72:856–63. Pubmed link , , , .
- 494 The role of IL‐22 and Th22 cells in human skin diseases. Dermatol Sci 2013 Oct;72(1):3–8. Cross Ref link .
- 495 Keratinocyte‐derived IL‐24 plays a role in the positive feedback regulation of epidermal inflammation in response to environmental and endogenous toxic stressors. Toxicol Appl Pharmacol Aug 2014;280(2):199–206. Cross Ref link Pubmed link , , , .
- 496 New IL‐17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL‐25. J Immunol 2002 Jul 1;169:443–53. Cross Ref link Pubmed link , , , et al.
- 497 IL‐27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. Immunity 2002 Jun;16:779–90. Cross Ref link Pubmed link , , , et al.
- 498 Interleukin‐28 and interleukin‐29: novel regulators of skin biology. J Interferon Cytokine Res Aug 2010;30(8):617–28. Cross Ref link Pubmed link , , .
- 499 Neuroimmune interactions in allergic skin diseases. Curr Opin Allergy Clin Immunol 2007 Oct;7:365–73. Cross Ref link Pubmed link , , , .
- 500 Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. Nat Immunol 2004 Jul;5:752–60. Cross Ref link Pubmed link , , , et al.
- 501 IL‐31: a new link between T cells and pruritus in atopic skin inflammation. J Allergy Clin Immunol 2006 Feb;117:411–17. Cross Ref link Pubmed link , , , et al.
- 502 IL‐31 is associated with cutaneous lymphocyte antigen‐positive skin homing T cells in patients with atopic dermatitis. J Allergy Clin Immunol 2006 Feb;117:418–25. Cross Ref link Pubmed link , , , et al.
- 503 The role of IL‐32 in cutaneous T‐cell lymphoma. J Invest Dermatol 2014 May;134(5):1428–35. Cross Ref link Pubmed link , , , et al.
- 504 Interleukin‐32 induces the differentiation of monocytes into macrophage‐like cells. Proc Natl Acad Sci U S A 2008 Mar 4;105:3515–20. Cross Ref link Pubmed link , , , et al.
- 505 Interleukin‐33 affects cytokine production by keratinocytes in vitiligo. Clin Exp Dermatol 2015 Mar;40(2):163–70. Cross Ref link Pubmed link , , , .
- 506 Interkeukin‐34, a cytokine crucial for the differentiation and maintenance of tissue resident macrophages and Langerhans cells. Eur J Immunol 2014 Jun;44(6):1575–81. Cross Ref link Pubmed link , .
- 507 The inhibitory cytokine IL‐35 contributes to regulatory T‐cell function. Nature 2007 Nov 22;450:566–9. Cross Ref link Pubmed link , , , et al.
- 508 Human CD4+ CD25+ Foxp3 +regulatory T cells do not constitutively express IL‐35. J Immunol 2008 Nov 15;181:6898–905. Cross Ref link Pubmed link , , , , .
- 509 Biology of IL‐36 cytokines and their role in disease . Semin Immunol 2013 Dec 15;25(6):458–65. Cross Ref link Pubmed link , .
- 510 IL‐37 ameliorates the inflammatory process in psoriasis by suppressing proinflammatory cytokine production. Immunology 2014 Feb 15;192(4):1815–23. Cross Ref link , , , , et al.
Interferons
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- 516 Cathepsin S activity is detectable in human keratinocytes and is selectively upregulated upon stimulation with interferon‐gamma. J Invest Dermatol 2002 Jul;119:44–9. Cross Ref link Pubmed link , , , et al.
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- 522 Alpha–nterferon increases immunoglobulin production in cultured human mononuclear leukocytes. J Immunol 1983 Mar;130:1215–19. Pubmed link , , , , .
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Tumour necrosis factor
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- 534 Shock and tissue injury induced by recombinant human cachectin. Science 1986 Oct 24;234:470–4. Cross Ref link Pubmed link , , , et al.
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- 543 Interferon‐gamma‐induced RANTES production by human keratinocytes is enhanced by IL‐1beta, TNF‐alpha, IL‐4 and IL‐13 and is inhibited by dexamethasone and tacrolimus. Dermatology 2001;202:239–45. Cross Ref link Pubmed link , , , , .
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Cytokine suppressors and inhibitors
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- 550 Native interleukin 1 inhibitors. Immunol Today 1989 Feb;10:61–6. Cross Ref link Pubmed link .
- 551 Soluble cytokine receptors: their role in immunoregulation. FASEB J 1991 Aug;5:2567–74. Pubmed link .
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- 554 Interleukin‐1 (IL‐1) receptor antagonist binds to the 80κDa IL‐1 receptor but does not initiate IL‐1 signal transduction. J Biol Chem 1991 Jun 5;266:10331–6. Pubmed link , , , .
- 555 Interleukin‐1 receptor antagonist competitively inhibits the binding of interleukin‐1 to the type II interleukin‐1 receptor. J Biol Chem 1991 Aug 5;266:14147–50. Pubmed link , , , .
- 556 Interleukin‐1 receptor antagonist activity of a human interleukin‐1 inhibitor. Nature 1990 Jan 25;343:336–40. Cross Ref link Pubmed link , , , et al.
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- 558 Interactions between cytokines and alpha 2‐macroglobulin. Immunol Today 1990 May;11:163–6. Cross Ref link Pubmed link .
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- 562 In vivo accumulation of a turnip crinkle virus defective interfering RNA is affected by alterations in size and sequence. J Virol 1991 Sep;65:4582–90. Pubmed link , .
Chemokines, Chemokine receptors
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- 567 Interleukin‐8 and related chemotactic cytokines – CXC and CC chemokines. Adv Immunol 1994;55:97–179. Cross Ref link Pubmed link , , .
- 568 Monocyte chemotactic protein 1 is a potent activator of human basophils. J Exp Med 1992 May 1;175:1271–5. Cross Ref link Pubmed link , , , .
- 569 Monocyte chemotactic and activating factor is a potent histamine‐releasing factor for human basophils. J Exp Med 1992 Feb 1;175:489–93. Cross Ref link Pubmed link , , , , .
- 570 Transcytosis and surface presentation of IL‐8 by venular endothelial cells. Cell 1997 Oct 31;91:385–95. Cross Ref link Pubmed link , , , et al.
- 571 Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8. Proc Natl Acad Sci U S A 1993 Aug 1;90:7158–62. Cross Ref link Pubmed link , , , , .
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- 574 Role of eosinophil‐chemotactic C‐C chemokines in cutaneous inflammation. J Leukoc Biol 1996 Jan;59:1–5. Pubmed link , , , .
- 575 Monocyte chemotactic protein MCP‐2 activates human basophil and eosinophil leukocytes similar to MCP‐3. J Immunol 1995 Apr 15;154:4166–72. Pubmed link , , , , , .
- 576 Functional expression of the eotaxin receptor CCR3 in T lymphocytes co‐localizing with eosinophils. Curr Biol 1997 Nov 1;7:836–43. Cross Ref link Pubmed link , , , et al.
- 577 Targeted disruption of the chemokine eotaxin partially reduces antigen‐induced tissue eosinophilia. J Exp Med 1997 Feb 17;185:785–90. Cross Ref link Pubmed link , , , , .
- 578 Involvement of CC chemokine ligand 18 (CCL18) in normal and pathological processes. J Leukoc Biol 2005 Jul;78:14–26. Cross Ref link Pubmed link , , .
- 579 CTACK, a skin‐associated chemokine that preferentially attracts skin‐homing memory T cells. Proc Natl Acad Sci U S A 1999 Dec 7;96:14470–5. Cross Ref link Pubmed link , , , et al.
- 580 Cutting edge: the orphan chemokine receptor G protein‐coupled receptor‐2 (GPR‐2, CCR10) binds the skin‐associated chemokine CCL27 (CTACK/ALP/ILC). J Immunol 2000 Apr 1;164:3465–70. Cross Ref link Pubmed link , , , et al.
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- 582 Neutrophil‐activating proteins in psoriasis. J Invest Dermatol 1992 Feb;98:241–7. Cross Ref link Pubmed link , , , .
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- 584 Recombinant human interferon‐inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J Exp Med 1993 Jun 1;177:1809–14. Cross Ref link Pubmed link , , , et al.
- 585 Epithelial neutrophil activating peptide‐78: a novel chemotactic cytokine for neutrophils in arthritis. J Clin Invest 1994 Sep;94:1012–18. Cross Ref link Pubmed link , , , et al.
- 586 Human herpesvirus KSHV encodes a constitutively active G‐protein‐coupled receptor linked to cell proliferation. Nature 1997 Jan 23;385:347–50. Cross Ref link Pubmed link , , , , .
- 587 Fusion of monocytes and macrophages with HIV‐1 correlates with biochemical properties of CXCR4 and CCR5. Nat Med 1999 Mar;5:303–8. Cross Ref link Pubmed link , , , , .
- 588 Impaired host defense, hematopoiesis, granulomatous inflammation and type 1‐type 2 cytokine balance in mice lacking CC chemokine receptor 1. J Exp Med 1997 Jun 2;185:1959–68. Cross Ref link Pubmed link , , , et al.
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- 590 The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. Nature 1999 Aug 19;400:776–80. Cross Ref link Pubmed link , , , et al.
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- 592 Beta‐defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science 1999 Oct 15;286:525–8. Cross Ref link Pubmed link , , , et al.
- 593 Broad spectrum chemokine antagonistic activity of a human poxvirus chemokine homolog. Proc Natl Acad Sci U S A 1998 May 26;95:6403–7. Cross Ref link Pubmed link , , .
- 594 Neutrophil and B cell expansion in mice that lack the murine IL‐8 receptor homolog. Science 1994 Jul 29;265:682–4. Cross Ref link Pubmed link , , , et al.
- 595 Delayed wound healing in CXCR2 knockout mice. J Invest Dermatol 2000 Aug;115:234–44. Cross Ref link Pubmed link , , , et al.
- 596 CXC chemokines in angiogenesis. J Leukoc Biol 2000 Jul;68:1–8. Pubmed link , , , et al.
Proteases
- 597 Thrombin signalling and protease‐activated receptors. Nature 2000 Sep 14;407:258–64. Cross Ref link Pubmed link .
- 598 Specificity of coagulation factor signaling. J Thromb Haemost 2003 Jul;1:1495–503. Cross Ref link Pubmed link , , .
- 599 Protease‐induced leukocyte chemotaxis and activation: roles in host defense and inflammation. J Med Invest 2001 Aug;48:133–41. Pubmed link , , , .
- 600 Role of mast cell chymase in allergen‐induced biphasic skin reaction. Biochem Pharmacol 2002 Oct 1;64:1187. Cross Ref link Pubmed link , , , et al.
- 601 Gamma‐secretase‐mediated proteolysis in cell‐surface‐receptor signalling. Nat Rev Mol Cell Biol 2002 Sep;3:673–84. Cross Ref link Pubmed link .
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- 603 Agonists of proteinase‐activated receptor 2 induce cytokine release and activation of nuclear transcription factor kappaB in human dermal microvascular endothelial cells. J Invest Dermatol 2002 Feb;118:380–5. Cross Ref link Pubmed link , , , et al.
- 604 Immunolocalization of protease‐activated receptor‐2 in skin: receptor activation stimulates interleukin‐8 secretion by keratinocytes in vitro. Immunology 1998 Jul;94:356–62. Cross Ref link Pubmed link , , , et al.
- 605 Thrombin and trypsin induce granulocyte–macrophage colony‐stimulating factor and interleukin‐6 gene expression in cultured normal human keratinocytes. Proc Assoc Am Physicians 1997 Mar;109:190–207. Pubmed link , , .
- 606 Tryptase: potential role in airway inflammation and remodeling. Am J Physiol Lung Cell Mol Physiol 2002 Feb;282:L193–6. Cross Ref link Pubmed link .
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- 608 Proteinase‐activated receptors: transducers of proteinase‐mediated signaling in inflammation and immune response. Endocr Rev 2005 Feb;26:1–43. Cross Ref link Pubmed link , , , et al.
- 609 Proinflammatory role of proteinase‐activated receptor‐2 in humans and mice during cutaneous inflammation in vivo. FASEB J 2003 Oct;17:1871–85. Cross Ref link Pubmed link , , , et al.
- 610 Proteinase‐activated receptor‐2 mediates itch: a novel pathway for pruritus in human skin. J Neurosci 2003 Jul 16;23:6176–80. Pubmed link , , , et al.
- 611 Agonists of proteinase‐activated receptor 2 induce inflammation by a neurogenic mechanism. Nat Med 2000 Feb;6:151–8. Cross Ref link Pubmed link , , , et al.
- 612 uPAR: a versatile signalling orchestrator. Nat Rev Mol Cell Biol 2002 Dec;3:932–43. Cross Ref link Pubmed link , .
- 613 Serum level of soluble urokinase‐type plasminogen activator receptor is a strong and independent predictor of survival in human immunodeficiency virus infection. Blood 2000 Dec 15;96:4091–5. Pubmed link , , , et al.
- 614 Functional involvement of urokinase‐type plasminogen activator receptor in pemphigus acantholysis. J Cutan Pathol 1998 Oct;25:469–74. Cross Ref link Pubmed link , , .
- 615 Urokinase‐generated plasmin activates matrix metalloproteinases during aneurysm formation. Nat Genet 1997 Dec;17:439–44. Cross Ref link Pubmed link , , , et al.
- 616 uPA, uPAR, PAI‐1: key intersection of proteolytic, adhesive and chemotactic highways? Immunol Today 1997 Sep;18:415–17. Cross Ref link Pubmed link .
- 617 LEKTI proteolytic processing in human primary keratinocytes, tissue distribution and defective expression in Netherton syndrome. Hum Mol Genet 2003 Oct 1;12:2417–30. Cross Ref link Pubmed link , , , et al.
- 618 Protease inhibitors: current status and future prospects. J Med Chem 2000;Feb 10;43:305–41. Cross Ref link Pubmed link , , .
- 619 Human and mouse proteases: a comparative genomic approach. Nat Rev Genet 2003 Jul;4:544–58. Cross Ref link Pubmed link , , , .
- 620 Development of a chymase inhibitor: pharmacological characterization of a chymase inhibitor in inflamed tissue remodeling and fibrosis. Jpn J Pharmacol 2002 Nov;90:206–9. Cross Ref link Pubmed link , .
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- 622 Role of matriptase, hepatocyte‐growth factor inhibitor‐1 and proteinase‐activated receptor‐2 in human skin cancer. J Invest Dermatol 2009 Jul;129(7):1816–23. Cross Ref link Pubmed link , , , .
- 623 Spink5‐deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity. Nat Genet 2005 Jan;37:56–65. Pubmed link , , , et al.
- 624 Human tissue kallikreins as promiscuous modulators of homeostatic skin barrier functions. Biol Chem 2008 Jun;389:669–80. Cross Ref link Pubmed link , .
- 625 Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity. J Invest Dermatol 2005 Sep;125:510–20. Cross Ref link Pubmed link , , , et al.
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- 627 Kallikrein‐related peptidases. Cell Mol Life Sci 2008 Jul;65:2019–38. Cross Ref link Pubmed link , .
- 628 Increased basal transepidermal water loss leads to elevation of some but not all stratum corneum serine proteases. Int J Cosmet Sci 2008 Dec;30:435–42. Cross Ref link Pubmed link , , , .
- 629 Endothelin‐converting enzyme‐1 regulates endosomal sorting of calcitonin receptor‐like receptor and beta‐arrestins. J Cell Biol 2007 Dec 3;179:981–97. Cross Ref link Pubmed link , , , et al.
- 630 Endothelin‐converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling. Proc Natl Acad Sci U S A 2007 Jul 10;104:11838–43. Cross Ref link Pubmed link , , , et al.
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Matrix metalloproteinases
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- 643 Matrix metalloproteinase‐19 is expressed by keratinocytes in psoriasis. Acta Derm Venereol 2003;83:108–14. Cross Ref link Pubmed link , , , et al.
- 644 Induction of matrix metalloproteinase‐9 secretion from human keratinocytes in culture by ultraviolet B irradiation. J Dermatol Sci 2003 Nov;33:105–11. Cross Ref link Pubmed link , , , , .
- 645 Histamine upregulates keratinocyte MMP‐9 production via the histamine H1 receptor. J Invest Dermatol 2008 Dec;128:2783–91. Cross Ref link Pubmed link , , , et al.
- 646 Induction of matrix metalloproteinase‐9 in keratinocytes by histamine. J Invest Dermatol 2008 Dec;128:2748–50. Cross Ref link Pubmed link .
- 647 Matrix metalloproteinase gelatinase B (MMP‐9) coordinates and effects epithelial regeneration. J Biol Chem 2002 Jan 18;277:2065–72. Cross Ref link Pubmed link , , , et al.
- 648 Conformational dependence of collagenase (matrix metalloproteinase‐1) up‐regulation by elastin peptides in cultured fibroblasts. J Biol Chem 2001 Feb 16;276:5222–7. Cross Ref link Pubmed link , , , et al.
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- 650 Modulation of keratinocyte‐derived MMP‐9 by IL‐13: a possible role for the pathogenesis of epidermal inflammation. J Invest Dermatol 2008 Jan;128:59–66. Cross Ref link Pubmed link , , , .
- 651 Inflammation in stasis dermatitis upregulates MMP‐1, MMP‐2 and MMP‐13 expression. J Dermatol Sci 2001 Apr;25:198–205. Cross Ref link Pubmed link , , , et al.
- 652 Propionibacterium acnes stimulates pro‐matrix metalloproteinase‐2 expression through tumor necrosis factor‐alpha in human dermal fibroblasts. J Invest Dermatol 2008 Apr;128:846–54. Cross Ref link Pubmed link , , , , , .
- 653 Increased inflammation delays wound healing in mice deficient in collagenase‐2 (MMP‐8). FASEB J 2007 Aug;21:2580–91. Cross Ref link Pubmed link , , , et al.
- 654 MMP19 is essential for T cell development and T cell‐mediated cutaneous immune responses. PLOS One 2008;3:e2343. Cross Ref link Pubmed link , , , et al.
- 655 Expression of MMP‐9, MMP‐10 and TNF‐alpha and lack of epithelial MMP‐1 and MMP‐26 characterize pyoderma gangrenosum. J Cutan Pathol 2007 Dec;34:889–98. Cross Ref link Pubmed link , , , .
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- 658 Collagenase expression is rapidly induced in wound‐edge keratinocytes after acute injury in human skin, persists during healing, and stops at re‐epithelialization. J Invest Dermatol 1995 Apr;104:479–83. Cross Ref link Pubmed link , , , .
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- 660 Interstitial collagenase is expressed by keratinocytes that are actively involved in reepithelialization in blistering skin disease. J Invest Dermatol 1995 Jun;104:982–8. Cross Ref link Pubmed link , , , , , .
- 661 Collagenase in wound healing: effect of wound age and type. J Invest Dermatol 1992 Dec;99:709–14. Cross Ref link Pubmed link , , , , .
- 662 Tissue inhibitor of metalloproteinases‐1 is decreased and activated gelatinases are increased in chronic wounds. J Invest Dermatol 1995 Feb;104:236–40. Cross Ref link Pubmed link , , , et al.
- 663 Characterization of biologic properties of wound fluid collected during early stages of wound healing. J Invest Dermatol 1992 Nov;99:559–64. Cross Ref link Pubmed link , , .
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- 669 Tetracyclines: nonantibiotic properties and their clinical implications. J Am Acad Dermatol 2006 Feb;54:258–65. Cross Ref link Pubmed link , .
Lysosomal mediators
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- 678 Lysosomal hydrolases of the epidermis. 2. Ester hydrolases. Br J Dermatol 1975 Oct;93:391–8. Cross Ref link Pubmed link , .
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- 680 Neutral proteinase of rabbit skin: an enzyme capable of degrading skin protein and inducing an inflammatory response. Biochim Biophys Acta 1974 May 20;350:1–12. Cross Ref link Pubmed link , .
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Radical oxygen species
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- 690 Reactive nitrogen and oxygen species in airway inflammation. Eur J Pharmacol 2001 Oct 19;429:251–62. Cross Ref link Pubmed link , , , .
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- 698 Roles of beta 2 integrins of rat neutrophils in complement‐ and oxygen radical‐mediated acute inflammatory injury. J Immunol 1992 Mar 15;148:1847–57. Pubmed link , , , et al.
- 699 Nitric oxide‐peroxynitrite‐poly(ADP‐ribose) polymerase pathway in the skin. Exp Dermatol 2002 Jun;11:189–202. Cross Ref link Pubmed link , , , et al.
- 700 An immunohistochemical assessment of the response of the psoriatic lesion to single and repeated applications of high‐dose dithranol cream. Skin Pharmacol Appl Skin Physiol 2002 Nov–Dec;15:393–400. Cross Ref link Pubmed link , , , , , .
- 701 Oxidative stress promotes blood cell‐endothelial cell interactions in the microcirculation. Cardiovasc Toxicol 2002;2:165–80. Cross Ref link Pubmed link , , , .
- 702 Mechano‐oxidative coupling by mitochondria induces proinflammatory responses in lung venular capillaries. J Clin Invest 2003 Mar;111:691–9. Cross Ref link Pubmed link , , , , .
- 703 Glutathione monoethyl ester ameliorates caerulein‐induced pancreatitis in the mouse. J Clin Invest 1992 Jan;89:109–16. Cross Ref link Pubmed link , , , .
- 704 Antioxidant and prooxidant mechanisms in the regulation of redox(y)‐sensitive transcription factors. Cell Signal 2002 Nov;14:879–97. Cross Ref link Pubmed link .
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- 707 Increased alveolar macrophage chemiluminescence and airspace cell superoxide production in active pulmonary sarcoidosis. J Lab Clin Med 1988 Aug;112:147–56. Pubmed link , , , .
Nitric oxide
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- 710 Formation of nitric oxide‐derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 1998 Jan 22;391:393–7. Cross Ref link Pubmed link , , , et al.
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- 712 Arginase modulates nitric oxide production in activated macrophages. Am J Physiol 1998 Jan;274:H342–8. Pubmed link , , .
- 713 Modulation of leukocyte‐endothelial interactions by reactive metabolites of oxygen and nitrogen: relevance to ischemic heart disease. Free Radic Biol Med 1998 Sep;25:404–33. Cross Ref link Pubmed link , , .
- 714 Nitric oxide inhibits neutrophil beta 2 integrin function by inhibiting membrane‐associated cyclic GMP synthesis. J Cell Physiol 1997 Jul;172:12–24. Cross Ref link Pubmed link , , , .
- 715 Inducible nitric oxide synthase‐deficient mice have enhanced leukocyte‐endothelium interactions in endotoxemia. FASEB J 1997 Oct;11:955–64. Pubmed link , , , et al.
- 716 Regulation of gene expression by nitric oxide. Pflugers Arch 2001 Jul;442:479–86. Cross Ref link Pubmed link , , .
- 717 Differential expression of three T lymphocyte‐activating CXC chemokines by human atheroma‐associated cells. J Clin Invest 1999 Oct;104:1041–50. Cross Ref link Pubmed link , , , et al.
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- 719 Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR‐stimulated double‐positive thymocytes. J Immunol 1997 ;158:4696–703. Pubmed link , , , et al.
- 720 Thymic dendritic cells express inducible nitric oxide synthase and generate nitric oxide in response to self‐ and alloantigens. J Immunol 2000 May 1;164:4649–58. Cross Ref link Pubmed link , , , et al.
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- 722 Nitric oxide induces apoptosis in mouse thymocytes. J Immunol 1995 Sep 15;155:2858–65. Pubmed link , , , , , .
- 723 Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite‐driven apoptotic death. J Immunol 1999 Mar 15;162:3356–66. Pubmed link , , , et al.
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- 725 Clinical and serologic manifestations of autoimmune disease in MRL‐lpr/lpr mice lacking nitric oxide synthase type 2. J Exp Med 1997 Aug 4;186:365–73. Cross Ref link Pubmed link , , , et al.
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- 727 Control of the autoimmune response by type 2 nitric oxide synthase. J Immunol 2001 Sep 1;167:3000–6. Cross Ref link Pubmed link , , , et al.
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Histamine
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- 737 Histamine enhances TGF‐beta1‐mediated suppression of Th2 responses. FASEB J 2003 Jun;17:1089–95. Cross Ref link Pubmed link , , , , , .
- 738 Histamine regulates T‐cell and antibody responses by differential expression of H1 and H2 receptors. Nature 2001 Sep 27;413:420–5. Cross Ref link Pubmed link , , , et al.
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- 741 Regulation of histamine‐mediated prostacyclin synthesis in cultured human vascular endothelial cells. Cell 1981 Jun;24:915–23. Cross Ref link Pubmed link , , , .
- 742 H2 histamine receptor‐mediated increase in intracellular Ca2+ in cultured human keratinocytes. J Dermatol Sci 1999 Sep;21:127–32. Cross Ref link Pubmed link , .
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Platelet‐activating factor
- 750 Properties of PAF‐acether‐induced platelet aggregation and secretion. Studies in gel‐filtered human platelets. Thromb Res 1983 Mar 15;29:595–608. Cross Ref link Pubmed link , , , .
- 751 Platelet‐activating factor (PAF) as a mediator of neutrophil‐platelet interactions in inflammation. Agents Actions 1981 Dec;11:545–7. Cross Ref link Pubmed link .
- 752 Acetyl glyceryl ether phosphorylcholine stimulates leukotriene B4 synthesis in human polymorphonuclear leukocytes. J Clin Invest 1982 Nov;70:1058–65. Cross Ref link Pubmed link , , .
- 753 Monocyte tethering by P‐selectin regulates monocyte chemotactic protein‐1 and tumor necrosis factor‐alpha secretion. Signal integration and NF‐kappa B translocation. J Clin Invest 1995 May;95:2297–303. Cross Ref link Pubmed link , , , , .
- 754 Accumulation of eosinophils in response to intracutaneous PAF‐acether and allergens in man. Lancet 1986 Jun 14;1:1378–9. Cross Ref link Pubmed link , .
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- 761 Dermal dendritic cells, and not Langerhans cells, play an essential role in inducing an immune response. J Immunol 2008 Mar 1;180:3057–64. Cross Ref link Pubmed link , , , , .
- 762 Platelet‐activating factor is crucial in psoralen and ultraviolet A‐induced immune suppression, inflammation, and apoptosis. Am J Pathol 2006 Sep;169:795–805. Cross Ref link Pubmed link , , , et al.
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Prostaglandins and thromboxanes, Leukotrienes
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- 766 Genetic and pharmacological analysis of prostanoid receptor function. J Clin Invest 2001 Jul;108:25–30. Cross Ref link Pubmed link , .
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- 768 Prostanoid receptors: structures, properties, and functions. Physiol Rev 1999 Oct;79:1193–226. Pubmed link , , .
- 769 Cyclooxygenase‐dependent signalling: molecular events and consequences. FEBS Lett 1999 Feb 19;445:1–5. Cross Ref link Pubmed link , , , .
- 770 Prostaglandins and leukotrienes as inflammatory mediators. Br Med Bull 1987 Apr;43:285–96. Pubmed link , .
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- 773 Altered prostaglandin E2 regulation of cytokine production in atopic dermatitis. J Immunol 1993 Sep 15;151:3345–52. Pubmed link , , , .
- 774 Prostacyclin and the vascular endothelium. Bull Eur Physiopathol Respir 1981;17:687–701. Pubmed link , .
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- 777 Effect of lipoxygenase metabolites of arachidonic acid on proliferation of human T cells and T cell subsets. J Immunol 1985 Feb;134:1125–9. Pubmed link , , .
- 778 15‐hydroxy‐5,8,11,13‐eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase. J Biol Chem 1980 Jul 10;255:5996–8. Pubmed link , , .
- 779 Dermis‐derived 15‐hydroxy‐eicosatetraenoic acid inhibits epidermal 12‐lipoxygenase activity. J Invest Dermatol 1986 Oct;87:494–8. Cross Ref link Pubmed link , , , , .
- 780 Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature 1997 Aug 14;388:678–82. Cross Ref link Pubmed link , , , et al.
- 781 Impaired bone resorption to prostaglandin E2 in prostaglandin E receptor EP4‐knockout mice. J Biol Chem 2000 Jun 30;275:19819–23. Cross Ref link Pubmed link , , , et al.
- 782 Prostaglandin D2 as a mediator of allergic asthma. Science 2000 Mar 17;287:2013–17. Cross Ref link Pubmed link , , , et al.
- 783 Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes. J Clin Invest 2001 Jul;108:15–23. Cross Ref link Pubmed link , , .
- 784 Leukotrienes, sphingolipids, and leukocyte trafficking. J Immunol 2003 Jul 1;171:5–10. Cross Ref link Pubmed link , , .
- 785 Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 2001 Nov 30;294:1871–5. Cross Ref link Pubmed link .
- 786 Leukotriene B4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues. Nat Immunol 2003 Oct;4:965–73. Cross Ref link Pubmed link , , , , .
- 787 T helper cell type 2 cytokines coordinately regulate immunoglobulin E‐dependent cysteinyl leukotriene production by human cord blood‐derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4. J Exp Med 2001 Jan 1;193:123–33. Cross Ref link Pubmed link , , , , .
- 788 Mast cell‐dependent migration of effector CD8+ T cells through production of leukotriene B4. Nat Immunol 2003 Oct;4:974–81. Cross Ref link Pubmed link , , , , .
- 789 Leukotriene B4 receptor BLT1 mediates early effector T cell recruitment. Nat Immunol 2003 Oct;4:982–90. Cross Ref link Pubmed link , , , et al.
- 790 Lipoxin A4 and lipoxin B4 stimulate the release but not the oxygenation of arachidonic acid in human neutrophils: dissociation between lipid remodeling and adhesion. J Cell Physiol 1990 Jun;143:512–23. Cross Ref link Pubmed link , , , .
- 791 Lipoxin recognition sites. Specific binding of labeled lipoxin A4 with human neutrophils. J Biol Chem 1992 Aug 15;267:16168–76. Pubmed link , , , .
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- 793 Actions of lipoxins A4 and B4 on signal transduction events in Friend erythroleukemia cells. Proc Soc Exp Biol Med 1992 Nov;201:169–73. Cross Ref link Pubmed link , , .
- 794 Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction. J Exp Med 1996 Jan 1;183:137–46. Cross Ref link Pubmed link , .
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- 799 A small molecule CRTH2 antagonist inhibits FITC‐induced allergic cutaneous inflammation. Int Immunol 2009 Jan;21:81–93. Cross Ref link Pubmed link , , , et al.
- 800 Prostaglandin E2 is a major soluble factor produced by stromal cells for preventing inflammatory cytokine production from dendritic cells. Int Immunol 2008 Sep;20:1219–29. Cross Ref link Pubmed link , , , et al.
Neuromediators
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- 802 Neurophysiological, neuroimmunological, and neuroendocrine basis of pruritus. J Invest Dermatol 2006 Aug;126:1705–18. Cross Ref link Pubmed link , , , , , .
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- 830 Somatostatin. N Engl J Med 1983 Dec 15;309:1495–501. Cross Ref link Pubmed link .
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Cell apoptosis and inflammation
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