Changes in dermal connective tissue due to ageing and photodamage

    Introduction and general description

    • 1  Kligman AM, Lavker RM. Cutaneous aging. The difference between intrinsic aging and photoaging. J Cutaneous Aging Cosmetic Dermatol 1988;1:512.
    • 2  Yaar M, Gilchrest BA. Photoageing: mechanism, prevention and therapy. Br J Dermatol 2007;157:87487. Cross Ref link Pubmed link
    • 3  Kaya G, Saurat JH. Dermatoporosis: a chronic cutaneous insufficiency fragility syndrome. Clinicopathological features, mechanism, prevention and potential treatments. Dermatology 2007;215:284294. Cross Ref link Pubmed link

    Wrinkles

    • 4  Smith JB, Fenske NA. Cutaneous manifestations and consequences of smoking. J Am Acad Dermatol 1996;34:71732. Cross Ref link Pubmed link
    • 5  Kligman AM, Zheng P, Lavker RM. The anatomy and pathogenesis of wrinkles. Br J Dermatol 1985;113:3742. Cross Ref link Pubmed link
    • 6  Tsuji T, Yorifuji T, Hamarta T, et al. Light and scanning electron microscopic studies on wrinkles in aged person's skin. Br J Dermatol 1986;114:32935. Cross Ref link Pubmed link
    • 7  Lavker RM. Structural alterations in exposed and unexposed skin. J Invest Dermatol 1979;73:5969. Cross Ref link Pubmed link
    • 8  Yin L, Morita A, Tsuji T. Skin aging induced by ultraviolet exposure and tobacco smoking: evidence from epidemiological and molecular studies. Photodermatol Photoimmunol Photomed 2001;17:17883. Cross Ref link Pubmed link

    Actinic elastosis

    • 9  Kligman AM. Early destructive effects of sunlight on human skin. J Am Acad Dermatol 1969;210:237780.
    • 10  Finlayson GR, Sams WM Jr, Smith JG. Erythema ab igne: a histopathological study. J Invest Dermatol 1966;46:1048. Cross Ref link Pubmed link
    • 11  Braverman IM, Fonferko E. Studies in cutaneous aging. II. The microvasculature. J Invest Dermatol 1982;78:4448. Cross Ref link Pubmed link
    • 12  Bonkevitch F, Souza PR. Cutis rhomboidalis protects skin from malignant epithelial tumors. Med Hypotheses 2014;82:6523. Cross Ref link Pubmed link
    • 13  Wojno T, Tenzel RR. Actinic comedonal plaque of the eye. Am J Ophthalmol 1983;96:6878. Cross Ref link Pubmed link
    • 14  Lugo A, Montalvo l, González JR, et al. Bullous solar elastosis. Am J Dermatopathol 2005;27:345. Cross Ref link Pubmed link
    • 15  John SM, Hamm H. Actinic comedonal plaque. A rare ectopic form of the Favre–Racouchot syndrome. Clin Exp Dermatol 1993;18:2568. Cross Ref link Pubmed link
    • 16  Carter VH, Constantine VS, Poole WL. Elastotic nodules of the antihelix. Arch Dermatol 1969;100:2825. Cross Ref link Pubmed link
    • 17  Requena L, Aguilar A, Sánchez YE. Elastotic nodules of the ears. Cutis 1989;44:4524. Pubmed link
    • 18  Weedon D. Elastotic nodules of the ear. J Cutan Pathol 1981;8:42933. Cross Ref link Pubmed link
    • 19  Davis BE, Koh HK. Faces going up in smoke. A dermatologic opportunity for cancer prevention. Arch Dermatol 1992;128:25562. Cross Ref link
    • 20  Gilchrest BA. A review of skin ageing and its medical therapy. Br J Dermatol 1996;135:86775. Cross Ref link Pubmed link
    • 21  Kligman LH. Connective tissue photo‐damage in hairless mice is potentially reversible. J Invest Dermatol 1987;88:S1217. Cross Ref link
    • 22  Moy LS, Murad H, Moy RL. Glycolic acid therapy, evaluation of efficacy and techniques in treatment of photodamaged lesions. Am J Cosmetic Surg 1993;10:913.
    • 23  Hubbard BA, Unger JG, Rohrich RJ. Reversal of skin aging with topical retinoids. Plast Reconstr Surg 2014;133;481e490e. Cross Ref link Pubmed link
    • 24  Singh M, Griffiths CEM. The use of retinoids in the treatment of photoaging. Dermatol Ther 2006;19:297305. Cross Ref link Pubmed link
    • 25  Kligman AM, Dogadkina D, Lavker RM. Effects of topical tretinoin on non‐sun‐exposed protected skin of the elderly. J Am Acad Dermatol 1993;29:2533. Cross Ref link Pubmed link
    • 26  Gilchrest BA. Turning back the clock: retinoic acid modifies intrinsic aging changes. J Clin Invest 1994;94:171112. Cross Ref link Pubmed link
    • 27  Lateef H, Stevens MJ, Varani J. All‐trans‐retinoic acid suppresses matrix metalloproteinase activity and increases collagen synthesis in diabetic human skin in organ culture. Am J Pathol 2004;165:16774. Cross Ref link Pubmed link
    • 28  Maddin S, Laurharanta J, Agache P et al. Isotretinoin improves the appearance of photodamaged skin: results of a 36‐week, multicenter, double‐blind, placebo‐controlled trial. J Am Acad Dermatol 2000;42:5663. Cross Ref link Pubmed link
    • 29  Phillips TJ, Gottlieb AB, Leyden JJ, et al. Efficacy of 0.1% tazarotene cream for the treatment of photodamage. Arch Dermatol 2002;138:148693. Pubmed link
    • 30  Pandel R, Poljšak B, Godic A, Dahmane R. Skin photoaging and the role of antioxidants in its prevention. ISRN Dermatol 2013; Article ID 930164. Pubmed link
    • 31  Farris P, Krutman J, Li YH, et al. Reservatrol: a unique antioxidant offering a multi‐mechanistic approach for treating aging skin. J Drugs Dermatol 2013;12:138994. Pubmed link
    • 32  Ang P, Barlow RJ. Non‐ablative laser resurfacing: a systematic review of the literature. Clin Exp Dermatol 2002;27:6305. Cross Ref link Pubmed link
    • 33  Watson REB, Craven NM, Kang S, et al. A short‐term screening assay, using fibrillin‐1 as a reporter molecule for photoageing repair agents. J Invest Dermatol 2001;116:6728. Cross Ref link Pubmed link
    • 34  Watson REB, Long SP, Bowden JJ, et al. Repair of photoaged dermal matrix by topical application of a cosmetic ‘antiageing’ product. Br J Dermatol 2008;158:4727. Cross Ref link Pubmed link

    Collagenous and elastotic marginal plaques of the hands

    • 35  Burks JW, Wise LJ, Clark WH. Degenerative collagenous plaques of the hands. Arch Dermatol 1960;82:3626. Cross Ref link Pubmed link
    • 36  Jordaan HF, Rossouw DJ. Digital papular calcific elastosis: a histopathological, histochemical and ultrastructural study of 20 patients. J Cutan Pathol 1990;17:35870. Cross Ref link Pubmed link
    • 37  Menegesha YM, Kayal JD, Swerlick RA. Keratoelastoidosis marginalis. J Cutan Med Surg 2002;6:235. Cross Ref link Pubmed link
    • 38  Rongioletti F, Betti R, Crosti C, et al. Marginal papular acrokeratodermas: a unified nosology for focal acral hyperkeratosis, acrokeratoelastoidosis and related disorders. Dermatology 1994;188:2831. Cross Ref link Pubmed link
    • 39  Calderone DC, Fenske NA. The clinical spectrum of actinic elastosis. J Am Acad Dermatol 1995;32:101624. Cross Ref link Pubmed link
    • 40  Todd D, Al‐Aboosi M, Hameed O, et al. The role of UV light in the pathogenesis of digital papular calcific elastosis. Arch Dermatol 2001;137:37981. Pubmed link
    • 41  Mortimore RJ, Conrad RJ. Collagenous and elastotic marginal plaques of the hands. Australas J Dermatol 2001;42:21113. Cross Ref link Pubmed link

    Adult colloid milium and colloid degeneration of the skin

    • 42  Mehregan D, Hooten J. Adult colloid milium: a case report and literature review. Int J Dermatol 2011;50:15314. Cross Ref link Pubmed link
    • 43  Innocenzi D, Barduagni F, Cerio R, Wolter M. UV‐induced colloid milium. Clin Exp Dermatol 1993;18:34750. Cross Ref link Pubmed link
    • 44  Dummer R, Laetsch B, Stutz S, et al. Elastosis colloidalis conglomerata (adult colloid milium, paracolloid of the skin) a maximal manifestation of actinic elastosis. Eur J Dermatol 2006;16:1636. Pubmed link
    • 45  Holzberger PC. Concerning adult colloid milium. Arch Dermatol 1960;82:71116. Cross Ref link Pubmed link
    • 46  Muscardin LM, Bellocci M, Balus K. Papuloverrucous colloid milium: an occupational variant. Br J Dermatol 2000;143:8847. Cross Ref link Pubmed link
    • 47  Findlay GH, Morrison JGL, Simson IW, et al. Exogenous ochronosis and pigmented colloid milium from hydroquinone bleaching creams. Br J Dermatol 1975;93:61322. Cross Ref link Pubmed link
    • 48  Hashimoto K, Miller F, Bereston ES. Colloid milium: histochemical and electron microscopic studies. Arch Dermatol 1972;105:68494. Cross Ref link Pubmed link
    • 49  Handfield‐Jones SE, Atherton D, Black M. Juvenile colloid milium. Br J Dermatol 1991;125:801. Cross Ref link
    • 50  Chowdhury MMV, Blackford S, Williams S. Juvenile colloid milium. Br J Dermatol 1999;141(Suppl. 55):1027.
    • 51  Hashimoto K, Nakayama H, Chimenti S, et al. Juvenile colloid milium. Immunohistochemical and ultrastructural studies. J Cutan Pathol 1989;16:16474. Cross Ref link Pubmed link
    • 52  Sanjuan EB, Planas G, Piquero J, et al. Colloid milium associated with multiple myeloma. Int J Dermatol 1994;33:7935. Cross Ref link Pubmed link
    • 53  Netscher DT, Sharma S, Kinner BM, Lyos A, Griego RD. Adult‐type colloid milium of hands and face successfully treated with dermabrasion. South Med J 1996;89:10047. Cross Ref link Pubmed link
    • 54  Ammirati CT, Giancola JM, Hruza GJ. Adult‐onset facial colloid milium successfully treated with the long‐pulsed Er:YAG laser. Dermatol Surg 2002;28:21519. Pubmed link

    Other causes of cutaneous atrophy

      Atrophy due to corticosteroids

      • 55  Henqqe VR, Ruzicka T, Schwartz RA, et al. Adverse effects of topical corticosteroids. J Am Acad Dermatol 2006;54:115. Cross Ref link Pubmed link
      • 56  Turpeinen M, Raitio H, Pelkonen AS, et al. Skin thickness in children treated with daily or periodical inhaled budesonide for mild persistent asthma. The Helsinki early intervention childhood asthma study. Pediatr Res 2010;67:2215. Cross Ref link Pubmed link
      • 57  Sarrni H, Hopsu‐Havu BK. The decrease of hyaluronate synthesis by anti‐inflammatory steroids in vivo. Br J Dermatol 1978;98:4459. Cross Ref link Pubmed link
      • 58  Averbeck M, Gebhardt C Anderegg U, et al. Suppression of hyaluran synthase 2 expression reflects the atrophogenic potential of glucocorticoids. Exp Dermatol 2010;19:7579. Cross Ref link Pubmed link
      • 59  Risteli J. Effect of prednisolone on the activities of intracellular enzymes of collagen biosynthesis in rat skin. Biochem Pharmacol 1977;26:12958. Cross Ref link
      • 60  Autio P, Oikarinen A, Melkko J, et al. Systemic glucocorticoids decrease the synthesis of type I and type III collagen in human skin in vivo, whereas isotretinoin has little effect. Br J Dermatol 1994;131:6603. Cross Ref link Pubmed link
      • 61  Oishi Y, Fu ZW, Ohnuki Y, et al. Molecular basis of the alteration in skin collagen metabolism in response to in vivo dexamethasone treatment: effects on the synthesis of collagen type I and III, collagenase, and tissue inhibitors of metalloproteinases. Br J Dermatol 2002;147:85968. Cross Ref link Pubmed link
      • 62  Werth VP, Kligman AM, Shi X, et al. Lack of correlation of skin thickness with bone density in patients receiving chronic glucocorticoid. Arch Dermatol Res 1998;290:38893. Cross Ref link Pubmed link
      • 63  Nuutinen P, Riekki R, Parikka M, et al. Modulation of collagen synthesis and mRNA by continuous and intermittent use of topical hydrocortisone in human skin. Br J Dermatol 2003;148:3945. Cross Ref link Pubmed link
      • 64  Koob TJ, Jeffrey JJ, Eisen AZ. Regulation of human skin collagenase activity by hydrocortisone and dexamethasone in organ culture. Biochem Biophys Res Commun 1974;61:10838. Cross Ref link Pubmed link
      • 65  Lehmann P, Zheng P, Lavker RM, et al. Corticosteroid atrophy in human skin. A study of light scanning and transmission electron microscopy. J Invest Dermatol 1983;81:16975. Cross Ref link Pubmed link
      • 66  Jablonska S, Groniowska M, Dabrowski J. Comparative evaluation of skin atrophy in man produced by topical corticosteroids. Br J Dermatol 1979;100:193206. Cross Ref link Pubmed link
      • 67  Barnes L, Kaya G, Rollason V. Topical corticosteroid‐induced skin atrophy: a comprehensive review. Drug Saf 2015;38:493509. Cross Ref link Pubmed link
      • 68  Burton JL, Winter GD. Experimentally induced steroid atrophy in the domestic pig and man. Br J Dermatol 1976;94(Suppl. 12):1079. Cross Ref link Pubmed link
      • 69  Dykes PF, Marks R. An appraisal of the methods used in the assessment of atrophy from topical corticosteroids. Br J Dermatol 1979;101:599609. Cross Ref link Pubmed link
      • 70  James MP, Black MH, Sparkes CG. Measurement of dermal atrophy induced by topical steroids using a radiographic technique. Br J Dermatol 1977;96:3035. Cross Ref link Pubmed link
      • 71  Marks R, Halprin K, Fukui K, et al. Topically applied triamcinolone and macromolecular synthesis by human epidermis. J Invest Dermatol 1971;56:4703. Cross Ref link Pubmed link
      • 72  Holze E, Plewig G. Effects of dermatitis, stripping and steroids on the morphology of corneocytes. J Invest Dermatol 1977;68:3506. Cross Ref link Pubmed link
      • 73  Pinnell S. Management of cutaneous atrophy after corticosteroid injection. J Am Acad Dermatol 1987;17:521. Cross Ref link Pubmed link
      • 74  McMichael AJ, Griffiths CEM, Talwar HS, et al. Concurrent application of tretinoin (retinoic acid) partially protects against corticosteroid‐induced epidermal atrophy. Br J Dermatol 1996;135:604. Cross Ref link Pubmed link
      • 75  Shumaker PR, Rao J, Goldman MP. Treatment of local, persistent cutaneous atrophy following corticosteroid injection with normal saline infiltration. Dermatol Surg 2005;31:13403. Cross Ref link Pubmed link
      • 76  Kaya G, Tran C, Sorg O, et al. Hyaluronate fragments reverse skin atrophy by a CD44‐dependent mechanism. PLOS Med 2006;3:e493. Cross Ref link Pubmed link
      • 77  Schäcke H, Zollner TM, Dӧcke WD, et al. Characterization of ZK245186, a novel selective glucocorticoid receptor agonist for the topical treatment of inflammatory skin diseases. Br J Pharmacol 2009;158:1088103. Cross Ref link Pubmed link

      Striae

      • 78  Stevanovic DV. Corticosteroid‐induced atrophy of the skin with telangiectasia. A clinical and experimental study. Br J Dermatol 1972;87:54856. Cross Ref link Pubmed link
      • 79  Shuster S. The cause of striae distensae. Acta Derm Venereol Suppl (Stockh) 1979;59(85):1619. Pubmed link
      • 80  Herxheimer H. Cutaneous striae in normal boys. Lancet 1953;ii:204. Cross Ref link
      • 81  Carr RD, Hamilton JF. Transverse striae of the back. Arch Dermatol 1969;99:2630. Cross Ref link Pubmed link
      • 82  Thiers H, Moulin G, Larive M. Les vergetures de la corticothérapie locale. Ann Dermatol Syphiligr (Paris) 1969;96:2936. Pubmed link
      • 83  Darvay A, Acland K, Lynn W, Russell‐Jones R. Striae formation in two HIV‐positive persons receiving protease inhibitors. J Am Acad Dermatol 1999;41:4679. Cross Ref link Pubmed link
      • 84  Zheng PS, Lauker RM, Lehmann P, et al. Morphologic investigations on the rebound phenomenon after corticosteroid‐induced atrophy in human skin. J Invest Dermatol 1984;82:34552. Cross Ref link Pubmed link
      • 85  Bertin C, Lopes‐Da Cunha A, Nkengne A, et al. Striae distensae are characterized by distinct microstructural features as measured by non‐invasive methods in vivo. Skin Res Technol 2014;20:816. Cross Ref link Pubmed link
      • 86  Zheng P, Lavker RM, Kligman AM. Anatomy of striae. Br J Dermatol 1985;112:18593. Cross Ref link Pubmed link
      • 87  Arem AJ, Kischer CW. Analyses of striae. Plast Reconstr Surg 1980;65:229. Cross Ref link Pubmed link
      • 88  De Paepe A, Devereux RB, Dietz HC, et al. Revised diagnostic criteria for the Marfan syndrome. Am J Med Genet 1996;62:41726. Cross Ref link Pubmed link
      • 89  Bergman R, Nevit MJ, Gescheidt‐Shoshany H, Pimienta AL, Reinstein E. Atrophic skin patches with abnormal elastic fibres as a presenting sign of the MASS phenotype associated with mutation in the fibrillin‐1 gene. JAMA Dermatol 2014;150(8):8859. Cross Ref link Pubmed link
      • 90  Agg B, Benke K, Szilveszter B, et al. Possible extracardiac predictors of aortic dissection in Marfan syndrome. BMC Cardiovasc Disord 2014;14:47. Cross Ref link Pubmed link
      • 91  Tung JY, Kiefer AK, Mullins M, et al. Genome‐wide association analysis implicates elastin microfibrils in the development of nonsyndromic striae distensae. J Invest Dermatol 2013;133:262831. Cross Ref link Pubmed link
      • 92  Poidevin LOS. Striae gravidarum. Their relation to adrenal cortical hyperfunction. Lancet 1959;ii:4368. Cross Ref link
      • 93  Chernovsky ME, Knox JM. Atrophic striae after occlusive corticosteroid therapy. Arch Dermatol 1964;90:1519. Cross Ref link Pubmed link
      • 94  Kikuchi I, Horikawa S. Perilymphatic atrophy of the skin. A side effect of topical corticosteroid injection therapy. Arch Dermatol 1974;109:5589. Cross Ref link Pubmed link
      • 95  McAvoy BR. No evidence for topical preparations in preventing stretch marks in pregnancy. Br J Gen Pract 2013;63:212. Cross Ref link Pubmed link
      • 96  Al‐Himdani S, Ud‐Din S, Gilmore S, et al. Striae distensae: a comprehensive revision and evidence‐based evaluation of prophylaxis and treatment. Br J Dermatol 2014;170:52747. Cross Ref link Pubmed link
      • 97  Heixsal D, Soirefmann M, Porto MD, et al. Superficial dermabrasion versus topical tretinoin on early striae distensae: a randomized pilot study. Dermatol Surg 2014;40:53744. Cross Ref link Pubmed link
      • 98  Shokeir H, El Bedewi A, Sayed S, et al. Efficacy of pulsed dye laser versus intense pulsed light in the treatment of striae distensae. Dermatol Surg 2014;40:63240. Pubmed link
      • 99  Goldman A, Rossato F, Prati C. Stretch marks: treatment using the 1,064nm Nd:YAG Laser. Dermatol Surg 2008;34:68691. Pubmed link
      • 100  Kou BJ, Lee DH, Kim MN, et al. Fractional photothermolysis for the treatment of striae distensae in Asian skin. Am J Clin Dermatol 2008;9:337. Cross Ref link Pubmed link
      • 101  Ud‐Din S, McAnelly SL, Bowring A, et al. A double blind controlled clinical trial assessing the effect of topical gels on striae distensae (stretch marks): a morphological and immunohistochemical study. Arch Dermatol Res 2013;305:60317. Cross Ref link Pubmed link

      Acquired poikiloderma

      • 102  Okazaki M, Kikuchi I. Radiodermatitis. An analysis of 43 cases. J Dermatol 1986;13:35665. Cross Ref link Pubmed link
      • 103  Carroll CL, Lang W, Snively B, et al. Development and validation of the Dermatomyositis Skin Severity Index. Br J Dermatol 2008;158:345350. Cross Ref link Pubmed link
      • 104  Bloom B, Marchbein S, Fischer M, et al. Poikilodermatous mycosis fungoides. Dermatol Online J 2012;18(12):4. Pubmed link

      Atrophic scars

      • 105  Leung AKC, Pinkao C, Suave RS. Scarring resulting from chickenpox. Pediatr Dermatol 2001;18:37880. Cross Ref link Pubmed link
      • 106  Murdoch ME, Hay RJ, Mackenzie CD, et al. A clinical classification and grading system of the cutaneous changes in onchocerciasis. Br J Dermatol 1993;129:2609. Cross Ref link Pubmed link
      • 107  Colomb D. Stellate spontaneous pseudoscars. Senile and presenile forms: especially those forms caused by prolonged corticoid therapy. Arch Dermatol 1972;105:5514. Cross Ref link Pubmed link
      • 108  Zac FG, Pai SH, Kanshepolsky J. Stellate spontaneous pseudoscars (Colomb). Arch Dermatol 1968;98:499501. Cross Ref link Pubmed link
      • 109  McCash S, Emanuel PO. Defining diabetic dermopathy. J Dermatol 2011;38(10):98892. Cross Ref link Pubmed link
      • 110  Cohen BA, Esterley NB, Nelson PF. Congenital erosive and vesicular dermatitis healing with reticulated supple scarring. Arch Dermatol 1985;121:3617. Cross Ref link Pubmed link
      • 111  Tlougan BE, Paller AS, Schaffer JV, et al. Congenital erosive and vesicular dermatosis with reticulated supple scarring: unifying clinical features. J Am Acad Dermatol 2013;69(6):90915. Cross Ref link Pubmed link
      • 112  Gupta AK, Rasmussen JE, Headington JT. Extensive congenital erosions and vesicles healing with reticulate scarring. J Am Acad Dermatol 1987;17:36976. Cross Ref link Pubmed link
      • 113  De Lange A, Bayet B, Debauche C, et al. Congenital erosive and vesicular dermatosis with reticulated scarring in a newborn: an innovative treatment using a silicone dressing. Pediatr Dermatol 2009;26:7358. Cross Ref link Pubmed link

      Spontaneous atrophic scarring of the cheeks

      • 114  Marks VJ, Miller OF. Atrophia maculosa varioliformis cutis. Br J Dermatol 1986;115:1059. Cross Ref link Pubmed link
      • 115  McCoriston LR, Roys HC. Atrophia maculosa varioliformis cutis. Arch Dermatol 1951;64:5961. Cross Ref link
      • 116  Paradisi M, Angelo C, Conti G, et al. Atrophia maculosa varioliformis cutis: a pediatric case. Pediatr Dermatol 2001;18:47880. Cross Ref link Pubmed link
      • 117  Kolenik SA, Perez MI, Davidson DM, et al. Atrophia maculosa varioliformis cutis. J Am Acad Dermatol 1994;30:83740. Cross Ref link Pubmed link
      • 118  Gordon PM, Doherty VR. Familial atrophia maculosa varioliformis cutis. Br J Dermatol 1996;134:9823. Cross Ref link Pubmed link
      • 119  Ou T, Wang B, Fang K. Familial atrophia maculosa varioliformis cutis: case report and pedigree analysis. Br J Dermatol 2005;153:8214. Cross Ref link Pubmed link

      Acrodermatitis chronica atrophicans

      • 120  Steere AC. Lyme disease. N Engl J Med 1989;321:58696. Cross Ref link Pubmed link
      • 121  Coulson IH. Acrodermatitis chronica atrophicans with coexisting.morphoea. Br J Dermatol 1989;121:2639. Cross Ref link Pubmed link
      • 122  Aberer E, Kersten A, Klade H. Heterogeneity of Borrelia burgdorferi in the skin. Am J Dermatopathol 1996;18:5719. Cross Ref link Pubmed link
      • 123  Flisiak I, Schwartz RA, Chodynicka B. Clinical features and specific immunological response against Borrelia afzelii in patients with acrodermatitis chronica atrophicans. J Med 1999;30:26778. Pubmed link
      • 124  Boehmer‐Andersson E, Hovmark A, Asbrink E. Acrodermatitis chronica atrophicans: histopathologic findings and clinical correlation in 111 cases. Acta Derm Venereol 1998;78:20713. Cross Ref link Pubmed link
      • 125  Asbrink E, Hovmark A. Successful cultivation of spirochaetes from the skin lesions of patients with erythema chronicum migrans and acrodermatitis chronicum atrophicans. Acta Pathol Microbiol Immunol Scand B 1985;93:1613. Pubmed link
      • 126  Asbrink E, Hovmark A. Early and late cutaneous manifestations of Ixodes borne borreliosis (Lyme borreliosis). Ann NY Acad Sci 1988;539:415. Cross Ref link Pubmed link
      • 127  Müller KE. Damage of collagen and elastic fibres by Borrelia burgdorferi: known and new clinical and histological aspects. Open Neurol J 2012;6:17986. Cross Ref link Pubmed link
      • 128  Mullegger RR, McHugh G, Ruthazar R. Differential expression of cytokine mRNA in skin specimens from patients with erythema migrans or acrodermatitis chronica atrophicans. J Invest Dermatol 2000;115:111523. Cross Ref link Pubmed link
      • 129  Grygorczuk S, Péter O, Kondrusik M, et al. Assessment of the different Borrelia burgdorferi sensu lato species in patients with Lyme borreliosis from north‐east Poland by studying preferential serologic response and DNA isolates. Ann Agric Environ Med 2013;20:219. Pubmed link
      • 130  Stinco G, Ruscio M, Bergamo S, et al. Clinical features of 705 Borrelia burgdorferi seropositive patients in an endemic area of northern Italy. Sci World J 2014;2014(1)414505. Cross Ref link
      • 131  Burgdorf WHC, Worret W, Schultka O. Acrodermatitis chronica atrophicans. Int J Dermatol 1979;18:595601. Cross Ref link Pubmed link
      • 132  Santos M, Ribiero‐Rodrigues R, Talhari C, et al. Presence of Borrelia burgdorferi ‘sensu lato’ in patients with morphoea from the Amazonia region in Brazil. Int J Dermatol 2011;50:13738. Cross Ref link Pubmed link
      • 133  Aberer E, Neumann R, Stanek G. Is localised scleroderma a Borrelia infection? Lancet 1985;ii:278. Cross Ref link
      • 134  Halkier‐Sorensen L. Antibodies to the Borrelia burgdorferi in patients with scleroderma. Acta Derm Venereol Suppl (Stockh) 1989;69:11619.
      • 135  Tee SI, Martinez‐Escanamé M, Zuriel D, et al. Acrodermatitis chronica atrophicans with pseudolymphomatous infiltrates. Am J Dermatopathol 2013;35:33842. Cross Ref link Pubmed link
      • 136  Fagrell B, Heiland RA, Howe TR. Acrodermatitis chronica atrophicans can mimic a peripheral vascular disorder. Acta Med Scand 1986;20:4858.
      • 137  Goos W, Schwarz‐Speck M. Acrodermatitis chronica atrophicans. Dermatologica 1972;145:28790. Cross Ref link Pubmed link
      • 138  Leverkas M, Finner AM, Pokrywka A, et al. Metastatic squamous carcinoma of the ankle in long‐standing untreated acrodermatitis chronica atrophicans. Dermatology 2008;217:21518. Cross Ref link Pubmed link
      • 139  Garbe C, Stein H, Dienemann D, Orfanos CE. Borrelia burgdorferi‐associated cutaneous B cell lymphoma. J Am Acad Dermatol 1991;24:58490. Cross Ref link Pubmed link
      • 140  Rees DHE, O'Connell S, Brown MM, et al. The value of serological testing for Lyme disease in the UK. Br J Rheumatol 1995;34:1326. Cross Ref link Pubmed link
      • 141  Aberer E, Breier F, Stanek G. Success and failure in the treatment of acrodermatitis chronica atrophicans. Infection 1996;24:857. Cross Ref link Pubmed link
      • 142  Stanek G, Strle F. Lyme borreliosis. Lancet 2003;362:163947. Cross Ref link Pubmed link
      • 143  Mullegger RR, Glatz M. Is serological follow‐up useful for patients with cutaneous Lyme borreliosis? Curr Probl Dermatol 2009;37:17882. Cross Ref link Pubmed link

      Atrophodermas

      • 144  Curth HO. The genetics of follicular atrophoderma. Arch Dermatol 1978;114:147983. Cross Ref link Pubmed link
      • 145  Hartman RD, Molho‐Pessach V, Schafer JV. Conradi–Hünermann–Happle syndrome. Dermatol Online J 2010;16(11):4. Pubmed link
      • 146  Viksnins P, Berlin A. Follicular atrophoderma and basal cell carcinoma. The Bazex syndrome. Arch Dermatol 1977;113:94851. Cross Ref link Pubmed link
      • 147  Moulin G, Hill MP, Guillaud V, et al. Bandes pigmentées atrophiques acquises suivant les lignes de Blaschko. Ann Dermatol Vénéréol 1992;119:72936.
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      Scleroatrophic syndrome of Huriez

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      Localized abdominal wall atrophy

      • 173  Orvis BR, Bottles K, Kogan BA. Testicular histology in the ‘prune belly’ syndrome. J Urol 1988;139:3357. Pubmed link
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      Paroxysmal haematoma of the finger

      • 176  Achenbach W. Das paroxysmale Handhämatom. Medizinische 1958;52:213840. Pubmed link
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      Panatrophy

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      • 189  Yoon J, Kim CW, Lee SH, et al. Correction of facial defects by autologous fat graft in local panatrophy. Eur J Dermatol 2012;22:71011. Pubmed link

      Facial hemiatrophy

      • 190  El‐Kehdy J, Abbas O, Rubeiz N. A review of Parry–Romberg syndrome. J Am Acad Dermatol 2012;67:76984. Cross Ref link Pubmed link
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      • 195  Handfield‐Jones SE, Peachey RDG, Moss ACH, et al. Ossification in linear morphoea with hemifacial atrophy: treatment by surgical excision. Clin Exp Dermatol 1988;13:3858. Cross Ref link Pubmed link
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      • 197  Bramley P, Forbes A. A case of progressive hemiatrophy presenting with spontaneous fractures of the lower jaw. BMJ 1960;i:14768. Cross Ref link
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      • 199  Sakamoto T, Oku T, Takigawa M. Gower's local panatrophy. Eur J Dermatol 1998;8:11617. Pubmed link
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      • 201  Rodby KA, Kaptein YE, Roring J, et al. Evaluating autologous lipofilling for Parry–Romberg syndrome‐associated defects: a systematic literature review and case report. Cleft Palate Craniofac J 2015, August 21. Pubmed link
      • 202  Chang Q, Li J, Dong Z, et al. Quantitative volumetric analysis of progressive hemifacial atrophy corrected using stromal vascular fraction‐supplemented autologous fat graft. Dermatol Surg 2013;39:146573. Pubmed link

      Disorders of elastic fibre degradation

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      • 207  Lewis KG, Bercovitch L, Dill SW, et al. Acquired disorders of elastic tissue: Part II. Decreased elastic tissue. J Am Acad Dermatol 2004;51:16585. Cross Ref link Pubmed link

      Lax skin

      • 208  El Khoury J, Kurban M, Abbas O. Elastophagocytosis: underlying mechanisms and associated cutaneous entities. J Am Acad Dermatol 2014;70:93444. Cross Ref link Pubmed link

      Acquired cutis laxa

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      • 211  Tsuji T, Imajo Y, Sawabe M, et al. Acquired cutis laxa concomitant with nephrotic syndrome. Arch Dermatol 1987;123:121116. Cross Ref link Pubmed link
      • 212  Ting HC, Foo MH, Wang F. Acquired cutis laxa and multiple myelomatosis. Br J Dermatol 1984;110:3637. Cross Ref link Pubmed link
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      • 214  Marchase P, Holbrook K, Pinnell SR. A familial cutis laxa syndrome with ultrastructural abnormalities of collagen and elastin. J Invest Dermatol 1980;75:399403. Cross Ref link Pubmed link
      • 215  Randle EHW, Muller S. Generalised elastolysis associated with systemic lupus erythematosus. J Am Acad Dermatol 1983;8:86973. Cross Ref link Pubmed link
      • 216  Rongioletti F, Cutolo M, Bondavalli P, Rebora A. Acral localized acquired cutis laxa associated with rheumatoid arthritis. J Am Acad Dermatol 2002;46:12830. Cross Ref link Pubmed link
      • 217  García‐Patos V, Pujol RM, Barnadas MA, et al. Generalized acquired cutis laxa associated with coeliac disease: evidence of immunoglobulin A deposits on the dermal elastic fibres. Br J Dermatol 1996;135:1304. Cross Ref link Pubmed link
      • 218  Hill VA, Seymour CA, Mortimer PS. Penicillamine‐induced elastosis perforans serpiginosa and cutis laxa in Wilson's disease. Br J Dermatol 2000;142:5601. Cross Ref link Pubmed link
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      • 220  Fornieri C, Quaglino D, Lungarella G, et al. Elastin production and degradation in cutis laxa acquisita. J Invest Dermatol 1994;103:5838. Cross Ref link Pubmed link
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      • 222  Kerl H, Berg G. Fatal penicillin‐induced generalized post‐inflammatory elastolysis (cutis laxa). Hautarzt 1975;26:1918. Pubmed link
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      • 224  Verhagen AR, Woerdemann MJ. Post‐inflammatory elastolysis and cutis laxa. Br J Dermatol 1975;92:18390. Cross Ref link Pubmed link
      • 225  Haider M, Alfadley A, Kadry R, et al. Acquired cutis laxa type II (Marshall syndrome) in an 18‐month‐old child: a case report. Pediatr Dermatol 2010;27:8991. Cross Ref link Pubmed link
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      Anetoderma

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      • 237  Kalogeramitros D, Gregoriou S, Makris M, et al. Secondary anetoderma associated with mastocytosis. Int Arch Allergy Immunol 2007;142:868. Cross Ref link Pubmed link
      • 238  Tatnall F, Rycroft R. Pityriasis versicolor with cutaneous atrophy. Clin Exp Dermatol 1985;10:25861. Cross Ref link Pubmed link
      • 239  Ozkan S, Fetil E, Izler F, et al. Anetoderma secondary to generalized granuloma annulare. J Am Acad Dermatol 2000;42:3358. Cross Ref link Pubmed link
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      • 242  Jubert C, Cosnes A, Clerici T, et al. Sjögren's syndrome and cutaneous B cell lymphoma revealed by anetoderma. Arthritis Rheum 1993;36:1334. Cross Ref link Pubmed link
      • 243  Sequrado M, Guerra‐Tapia A, Zarco C, et al. Anetoderma secondary to cutaneous B‐cell lymphoma. Clin Exp Dermatol 2006;31:1301. Cross Ref link Pubmed link
      • 244  Requena L, González‐Guerra E, Angulo J, et al. Anetodermic mycosis fungoides: a new clinicopathological variant of mycosis fungoides. Br J Dermatol 2008;158:15762. Pubmed link
      • 245  Prizant TL, Lucky AW, Frieden IJ, et al. Spontaneous atrophic patches in extremely premature infants. Anetoderma of prematurity. Arch Dermatol 1996;132:6714. Cross Ref link Pubmed link
      • 246  Cartlidge PH, Fox PE, Rutter N. The scars of newborn intensive care. Early Hum Dev 1990;21:110. Cross Ref link Pubmed link
      • 247  Shames BS, Nassif A, Bailey CS, et al. Secondary anetoderma involving a pilomatrixoma. Am J Dermatopathol 1994;16:55760. Cross Ref link Pubmed link
      • 248  Page EH, Assaad M. Atrophic dermatofibroma and dermatofibrosarcoma protuberans. J Am Acad Dermatol 1987;17:94750. Cross Ref link Pubmed link
      • 249  Gamo R, Ortiz‐Romero P, Sopeno J, et al. Anetoderma developing in juvenile xanthogranuloma. Int J Dermatol 2005;44:5036. Cross Ref link Pubmed link
      • 250  Cockayne SE, Gawkrodger DJ. Hamartomatous congenital naevi showing secondary anetoderma‐like changes. J Am Acad Dermatol 1998;39:8435. Cross Ref link Pubmed link
      • 251  Davis W. Wilson's disease and penicillamine‐induced anetoderma. Arch Dermatol 1977;113:9767. Cross Ref link
      • 252  Peterman A, Scheel M, Sams WM Jr, et al. Hereditary anetoderma. J Am Acad Dermatol 1996;35:9991000. Cross Ref link Pubmed link
      • 253  Zellman GL, Levy ML. Congenital anetoderma in twins. J Am Acad Dermatol 1997;36:4835. Cross Ref link Pubmed link
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      • 255  Hofer T, Golderberger D, Itin PH. Anetoderma and borreliosis: is there a pathogenic relationship? Eur J Dermatol 2003;13:399401. Pubmed link
      • 256  Venencie PY, Winkelmann RK, Moore BA. Ultrastructural findings in the skin lesions of patients with anetoderma. Acta Derm Venereol Suppl (Stockh) 1984;64:11220.
      • 257  Venencie PY, Winkelmann RK. Monoclonal antibody studies in the skin lesions of patients with anetoderma. Arch Dermatol 1985;121:7479. Cross Ref link Pubmed link
      • 258  Ghomrasseni S, Dridi M, Gogly B, et al. Anetoderma: an altered balance between metalloproteinases and tissue inhibitors of metalloproteinases. Am J Dermatopathol 2002;24:11829. Cross Ref link Pubmed link
      • 259  Kossard S, Kronman KR, Dicken CH, et al. Inflammatory macular atrophy. Immunofluorescence and ultrastructural findings. J Am Acad Dermatol 1979;1:32534. Cross Ref link Pubmed link
      • 260  Werth VP. Decay‐accelerating factor in human skin is associated with elastic fibers. J Invest Dermatol 1988;91:51116. Cross Ref link Pubmed link
      • 261  Haider M, Alenazi M, Almutawa A, et al. Lupus erythematosus‐associated primary and secondary anetoderma. J Cutan Med Surg 2012;16:647. Pubmed link
      • 262  De Bracco MM, Bianchi CA, Bianchi O, et al. Hereditary complement (C2) deficiency with discoid lupus erythematosus and idiopathic anetoderma. Int J Dermatol 1979;18:71315. Cross Ref link Pubmed link
      • 263  Ryll‐Nardzewski C. Remarques sur le lupus érythémate profond et sur l'anetodermie érythématoide. Ann Dermatol Syphiligr (Paris) 1960;87:62736. Pubmed link
      • 264  Schnitzler L, Sayag J. Pseudotumoral lupus anetoderma and infantile chorea. Ann Dermatol Vénéréol 1988;115:67985.
      • 265  Randle HW, Muller S. Generalized elastolysis associated with systemic lupus erythematosus. J Am Acad Dermatol 1983;8:86973. Cross Ref link Pubmed link
      • 266  Bergman R, Friedman‐Birnbaum R. An immunofluorescence study of primary anetoderma. Clin Exp Dermatol 1990;15:12430. Cross Ref link Pubmed link
      • 267  Hodak E, Shamai‐Lubovitz O, David M, et al. Primary anetoderma associated with a wide‐spectrum of autoimmune abnormalities. J Am Acad Dermatol 1991;25:41518. Cross Ref link Pubmed link
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      Mid‐dermal elastolysis, Upper dermal elastolysis

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      • 279  Harmon CB, Su WPD, Gagne EJ, et al. Ultrastructural evaluation of mid‐dermal elastolysis. J Cutan Pathol 1994;21:2338. Cross Ref link Pubmed link
      • 280  Varadi DP, Saqueton AC. Perifollicular elastolysis. Br J Dermatol 1970;83:14350. Cross Ref link Pubmed link
      • 281  Sterling JC, Coleman N, Pye RJ. Mid‐dermal elastolysis. Br J Dermatol 1994;130:5026. Cross Ref link Pubmed link
      • 282  Tajima S, Imazumi T, Kojiya H, et al. Elastin metabolism in skin fibroblasts explanted from a patient with mid‐dermal elastolysis. Br J Dermatol 1999;140:7524. Pubmed link
      • 283  Maghraoui G, Grossin M, Crickx B, et al. L'elastolyse acquise du derme moyen. Ann Dermatol Vénéréol 1994;121:25965.
      • 284  Dick GF. Elastolytic activity of P. acnes and Staph. epidermidis in acne and normal skin. Acta Derm Venereol Suppl (Stockh) 1976;56:27982.
      • 285  Wagner G, Sachse MM. Elastolysis mediodermalis: a case report and review of the literature. J Dtsch Dermatol Ges 2011;9:81014. Pubmed link
      • 286  Eaton PA, Knable AL, Callen JP. Mid‐dermal elastolysis in a patient undergoing hemodialysis. Cutis 2009;83:1414. Pubmed link
      • 287  Cutillas E, Ferrando FJ, Marli ME, et al. Reticular variant of mid‐dermal elastolysis after insertion of a pacemaker. Clin Exp Dermatol 2010;35:498500. Cross Ref link Pubmed link
      • 288  Lewis KG, Dill SW, Wilkel CS, et al. Mid‐dermal elastolysis preceded by acute neutrophilic dermatosis. J Cutan Pathol 2004;31:726. Cross Ref link Pubmed link
      • 289  Bayle‐Lebey P, Periole B, Daste G, et al. Acquired localized elastolysis associated with varicose veins. Clin Exp Dermatol 1995;20:4925. Cross Ref link Pubmed link
      • 290  Posada C, No N, De la Torre C, Flórez A. Reticular variant of mid‐dermal elastolysis. Australas J Dermatol 2013;54:6971. Cross Ref link Pubmed link
      • 291  Cohen PR, Tschen JA. Linear lumbar localised lysis of elastin fibres: a distinctive clinical presentation of mid‐dermal elastolysis. J Clin Aesthet Dermatol 2013;6:329. Pubmed link
      • 292  Hashimoto K, Tye MJ. Upper dermal elastolysis; a comparative study with mid‐dermal elastolysis. J Cutan Pathol 1994;21:53340. Cross Ref link Pubmed link
      • 293  Newlove T, Tzu J, Meehan S. Papillary dermal elastosis. Dermatol Online J 2011;17(10):12. Pubmed link
      • 294  Rongioletti F, Izakovic J, Romanelli P, et al. Pseudoxanthoma elasticum‐like papillary dermal, elastolysis: a large case series with clinicopathological correlation. J Am Acad Dermatol 2012;67:12835. Cross Ref link Pubmed link
      • 295  Wang AR, Lewis K, Lewis M, et al. Papillary dermal elastosis: a unique elastic tissue disorder or an unusual manifestation of pseudoxanthoma elasticum‐like papillary dermal elastolysis? J Cutan Pathol 2009;36:101013. Cross Ref link Pubmed link
      • 296  Gambichler T. Mid‐dermal elastolysis revisited. Arch Dermatol Res 2010;302:8593. Cross Ref link Pubmed link

      Blepharochalasis, Ascher syndrome

      • 297  Jordan DR. Blepharochalasis syndrome: a proposed pathophysiologic mechanism. Can J Ophthalmol 1992;27:1015. Pubmed link
      • 298  Tepaszto I, Liszkay L, Vass Z. Some data on the pathogenesis of blepharochalasis. Acta Ophthalmol (Copenh) 1963;41:16775. Cross Ref link Pubmed link
      • 299  Kaneoya K, Momota Y, Hatamochi A, et al. Elastin gene expression in blepharochalasis. J Dermatol 2005;32:269. Cross Ref link Pubmed link
      • 300  Grasseger A, Romani N, Fritsch P, et al. Immunoglobulin A (IgA) deposits in lesional skin of a patient with blepharochalasis. Br J Dermatol 1996;135:7915. Cross Ref link Pubmed link
      • 301  Dózsa A, Károlyi ZS, Degrell P. Bilateral blepharochalasis. J Eur Acad Dermatol Venereol 2005;19:7258. Cross Ref link Pubmed link
      • 302  Brazin SA. Unilateral blepharochalasis. Arch Dermatol 1979;115:47981. Cross Ref link Pubmed link
      • 303  Harris WA, Dortzbach RK. Levator tuck. A simplified blepharoptosis procedure. Ann Ophthalmol 1975;7:8738. Pubmed link
      • 304  Findlay GH. Idiopathic enlargements of the lips: cheilitis granulomatosa, Ascher's syndrome and double lip. Br J Dermatol 1954;66:12938. Cross Ref link Pubmed link
      • 305  Papanayotou PH, Hatzoitis JC. Ascher's syndrome: report of a case. Oral Surg Oral Med Oral Pathol 1973;35:46771. Cross Ref link Pubmed link
      • 306  Pitanguy I. Ascher's syndrome. Head Neck Surg 1988;10:30910. Cross Ref link Pubmed link
      • 307  Halling F, Sandrock D, Merten HA, et al. Das Ascher syndrome. Dtsch Z Mund Kiefer Gesichtschir 1991;15:4404. Pubmed link
      • 308  Ali K. Ascher syndrome: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:e268. Cross Ref link Pubmed link
      • 309  Ramesh BA. Ascher syndrome: review of literature and case report. Indian J Plast Surg 2011;44:1479. Cross Ref link Pubmed link
      • 310  Shah‐Desai S, Sandy C, Collin R. Lax eyelid syndrome or ‘progeria’ of eyelid tissues. Orbit 2004;23:312. Cross Ref link Pubmed link

      Actinic granuloma and annular elastolytic giant cell granuloma

      • 311  Hanke CW, Bailin PL, Roenigk HH. Annular elastolytic giant cell granuloma: a clinicopathologic study of five cases and a review of similar entities. J Am Acad Dermatol 1979;1:41321. Cross Ref link Pubmed link
      • 312  Gutiérrez‐González E, Pereiro M, Toribio J. Elastolytic actinic giant cell granuloma. Dermatol Clin 2015;33:33141. Cross Ref link Pubmed link
      • 313  Aso Y, Izaki S, Teraki Y. Annular elastolytic giant cell granuloma associated with diabetes mellitus: a case report and review of the Japanese literature. Clin Exp Dermatol 2011;36:91719. Cross Ref link Pubmed link
      • 314  Dowling GB, Wilson‐Jones E. Atypical (annular) necrobiosis lipoidica of the face and scalp. Dermatologica 1967;135:1126. Cross Ref link Pubmed link
      • 315  Wilson‐Jones E. Necrobiosis lipoidica presenting on the face and scalp. Trans St John's Hosp Dermatol Soc 1971;57:20320.
      • 316  Campos‐Munoz L, Diaz‐Diaz RM, Quesada‐Cortes A, et al. Annular elastolytic giant cell granuloma: a case report located in non‐sun exposed areas. Actas Dermosifiliogr 2006;97:5335. Cross Ref link Pubmed link
      • 317  Ishibashi A, Yokoyama A, Hirano K. Annular elastolytic giant cell granuloma occurring in covered areas. Dermatologica 1987;174:2937. Cross Ref link Pubmed link
      • 318  Muramatsu T, Shirai T, Yamashina Y, et al. Annular elastolytic giant cell granuloma: an unusual case with lesions arising in non‐sun‐exposed areas. J Dermatol 1987;14:548. Cross Ref link Pubmed link
      • 319  Pestoni C, Pereiro M, Toribio J. Annular elastolytic giant cell granuloma produced on an old burn scar and spreading after a mechanical trauma. Acta Derm Venereol 2003;83:31213. Cross Ref link Pubmed link
      • 320  Ozkaya‐Bayazit E, Buyukbabani N, Baykal C, et al. Annular elastolytic giant cell granuloma: sparing of a burn scar and successful treatment with chloroquine. Br J Dermatol 1999;140:52530. Cross Ref link Pubmed link
      • 321  Davies MG, Newman P. Actinic granulomata in a young woman following prolonged sunbed usage. Br J Dermatol 1997;136:7978. Cross Ref link Pubmed link
      • 322  Lim DS, Triscott J. O'Brien's actinic granuloma in association with prolonged doxycycline phototoxicity. Australas J Dermatol 2003;44:6770. Cross Ref link Pubmed link
      • 323  Garg A, Kundu RV, Plotkin O, Aronson IK. Annular elastolytic giant cell granuloma heralding onset and recurrence of acute myelogenous leukemia. Arch Dermatol 2006;142:5323. Cross Ref link Pubmed link
      • 324  Al‐Hoqail IA, Al‐Ghamdi AM, Martinka M, et al. Actinic granuloma is a unique and distinct entity: a comparative study with granuloma annulare. Am J Dermatopathol 2002;24:20912. Cross Ref link Pubmed link
      • 325  McGrae JD. Actinic granuloma: a clinical, histopathologic and immunocytochemical study. Arch Dermatol 1986;122:438. Cross Ref link Pubmed link
      • 326  O'Brien JP. Actinic granuloma: an annular connective tissue disorder affecting sun and heat‐damaged (elastotic) skin. Arch Dermatol 1975;111:46070. Cross Ref link Pubmed link
      • 327  Prendiville J, Griffiths WAD, Russell‐Jones R. O'Brien's actinic granuloma. Br J Dermatol 1985;113:3538. Cross Ref link Pubmed link
      • 328  Limas C. The spectrum of primary cutaneous elastolytic granulomas and their distinction from granuloma annulare: a clinicopathological analysis. Histopathology 2004;44:27782. Cross Ref link Pubmed link
      • 329  Berliner JG, Haemel A, Le Boit PE, et al. The sarcoidal variant of annular elastolytic granuloma. J Cutan Pathol 2013;49:91720. Cross Ref link
      • 330  Ratnavel RC, Grant JW, Handfield‐Jones SE, Norris PG. O'Brien's actinic granuloma: response to isotretinoin. J R Soc Med 1995;88:528P529P. Pubmed link
      • 331  Stefanaki C, Panagiotopoulos A, Kostakis P, et al. Actinic granuloma successfully treated with acitretin. Int J Dermatol 2005;44:1636. Cross Ref link Pubmed link
      • 332  Rongioletti F, Baldari M, Burlando M, et al. Papular elastolytic giant cell granuloma: report of a case associated with monoclonal gammopathy and responsive to topical tacrolimus. Clin Exp Dermatol 2010;35:1458. Cross Ref link Pubmed link

      Granuloma multiforme

      • 333  Kumari R, Thappa DM, Chougule A, Adityan B. Granuloma multiforme: a report from India. Indian J Dermatol Venereol 2009;75:2969. Cross Ref link
      • 334  Leiker DL, Kok SH, Spaas JAJ. Granuloma multiforme: a new skin disease resembling leprosy. Int J Lepr 1964;32:36876. Pubmed link
      • 335  Marshall J, Weber HW, Kok SH. Granuloma multiforme (Leiker). Dermatologica 1967;134:193207. Cross Ref link Pubmed link
      • 336  Leiker DL, Ziedses des Plantes M. Granuloma multiforme in Kenya. East Afr Med J 1967;44:42936. Pubmed link
      • 337  Allenby CF, Wilson Jones E. Granuloma multiforme. Trans St John's Hosp Dermatol Soc 1969;55:8898.
      • 338  Cherian S. Granuloma multiforme in India. Int J Lepr 1990;58:71921.
      • 339  Verhagen ARHB, Koten JW, Chaddah VK, Patel RI. Skin diseases in Kenya: a clinical and histopathological study of 3168 patients. Arch Dermatol 1968;98:57786. Cross Ref link Pubmed link
      • 340  Garrett AS. Granuloma multiforme (called Nkanu disease in the 1940s and Mkar disease in 1964). Int J Lepr 1999;67:1724.
      • 341  Cherian S. Is granuloma multiforme a photodermatosis? Int J Dermatol 1994;33:212. Cross Ref link Pubmed link

      Other elastolytic conditions

      • 342  Mattox AR, Marshall JA, Guo A. Granulomatous mycosis fungoides with clinical features of granulomatous slack skin. Cutis 2014;93:e45. Pubmed link
      • 343  Jawed SI, Myskowski PL, Horwitz S, et al. Primary cutaneous T cell lymphoma (mycosis fungoides and Sézary syndrome): Part 1. Diagnosis: clinical and histopathologic features and new molecular and biologic markers. J Am Acad Dermatol 2014;70:205e116. Cross Ref link

      Acquired pseudoxanthoma elasticum‐like syndromes

        Perforating pseudoxanthoma elasticum

        • 344  Premathala S, Yesudian P, Thambiah AS. Periumbilical pseudoxanthoma elasticum with transepithelial elimination. Int J Dermatol 1982;10:6045. Cross Ref link
        • 345  Kazakis AM, Parish WR. Periumbilical perforating pseudoxanthoma elasticum. J Am Acad Dermatol 1988;19:3848. Cross Ref link Pubmed link
        • 346  Somarsundaram V, Premathala S, Rao NR, et al. Periumbilical perforating pseudoxanthoma elasticum. Int J Dermatol 1987;26:5367. Cross Ref link Pubmed link
        • 347  Budania A, De D, Saikia UN, Kanwar AJ, Mahajan R, Yadav S. Periumbilical perforating pseudoxanthoma elasticum: an acquired perforating disorder. Int J Dermatol 2012;51:43941. Cross Ref link Pubmed link
        • 348  Nickoloff BJ, Noodleman FR, Abel EA. Perforating pseudoxanthoma elasticum associated with chronic renal failure and haemodialysis. Arch Dermatol 1985;121:13212. Cross Ref link Pubmed link
        • 349  Lund HZ, Gilbert CF. Perforating pseudoxanthoma elasticum. Its distinction from elastosis perforans serpiginosa. Arch Pathol Lab Med 1976;100:5446. Pubmed link
        • 350  Pugashetti R, Shinkai K, Ruben BS et al. Calcium may preferentially deposit in areas of elastic tissue damage. J Am Acad Dermatol 2011;64:296301. Cross Ref link Pubmed link
        • 351  Rongioletti F, Izakovic J, Romanelli P, et al. Pseudoxanthoma elasticum‐like papillary dermal, elastolysis: a large case series with clinicopathological correlation. J Am Acad Dermatol 2012;67:12835. Cross Ref link Pubmed link
        • 352  Sueki H, Amemiya M, Watanaba H, et al. Spontaneous resolution in a case of pseudo‐pseudoxanthoma elasticum. Br J Dermatol 2001;144:21315. Cross Ref link Pubmed link

        Acquired pseudoxanthoma elasticum

        • 353  Burge S, Ryan T. Penicillamine‐induced pseudo‐pseudoxanthoma elasticum in a patient with rheumatoid arthritis. Clin Exp Dermatol 1988;13:2558. Cross Ref link Pubmed link
        • 354  Na SY, Choi M, Kim MJ, Lee JH, Cho S. Penicillamine‐induced elastosis perforans serpiginosa and cutis laxa in a patient with Wilson's disease. Ann Dermatol 2010;22:46871. Cross Ref link Pubmed link
        • 355  Light N, Meyrick‐Thomas RH, Stephens A, et al. Collagen and elastin changes in d‐penicillamine‐induced pseudoxanthoma elasticum‐like skin. Br J Dermatol 1986;114:3818. Cross Ref link Pubmed link
        • 356  Meyrick‐Thomas RH, Kirby JDT. Elastosis perforans serpiginosa and pseudoxanthoma elasticum‐like skin changes due to D‐penicillamine. Clin Exp Dermatol 1985;10:38691. Cross Ref link Pubmed link
        • 357  Mainetti C, Masouyé I, Saurat JH. Pseudoxanthoma elasticum‐like lesions in the L‐tryptophan‐ induced eosinophilia‐myalgia syndrome. J Am Acad Dermatol 1991;24:6578. Cross Ref link Pubmed link
        • 358  Winkelmann RK, Peters MS, Venencie PY. Amyloid elastosis. A new cutaneous and systemic pattern of amyloidosis. Arch Dermatol 1985;121:498502. Cross Ref link Pubmed link
        • 359  Vecchietti G, Masouyé I, Salomon D, et al. An unusual form of primary systemic amyloidosis: amyloid elastosis. Report of a case treated by haematopoietic cell transplantation. Br J Dermatol 2003;145:1549. Cross Ref link
        • 360  Fabbri E, Forni GL, Guerrini G, et al. Pseudoxanthoma elasticum‐like syndrome and thalassaemias: an update. Dermatol Online J 2009;15(7):7. Pubmed link
        • 361  Barteselli G, Dell'arti L, Finger RP, et al. The spectrum of ocular alterations in patients with b‐thalassaemia syndrome suggest a pathology similar to pseudoxanthoma elasticum. Ophthalmology 2014;121:70918. Cross Ref link Pubmed link

        Saltpetre disease

        • 362  Christensen OB. An exogenous variety of pseudoxanthoma elasticum in old farmers. Acta Derm Venereol Suppl (Stockh) 1978;58:31922.
        • 363  Neilson AO, Christensen OB, Hentzer B, et al. Saltpetre‐induced dermal changes electron microscopically indistinguishable from pseudoxanthoma elasticum. Acta Derm Venereol Suppl (Stockh) 1978;58:3237.
        • 364  Neri I, Marzaduri S, Berdazzi F, et al. Exogenous pseudoxanthoma elasticum: a new case in an old farmer. Acta Derm Venereol 1993;78:1534.

        Acrokeratoelastoidosis

        • 365  Costa OG. Ackrokeratoelastoidosis. Arch Dermatol Syphilol 1954;70:22831. Cross Ref link
        • 366  Rubegni P, De Aloe G, Romano C, Flori ML, Fimiani M. Acrokeratoelastoidosis: a report of two sporadic cases. Clin Exp Dermatol 1997;22:624. Pubmed link
        • 367  Rongioletti F, Betti R, Crosti C, Rebora A. Marginal papular acrokeratodermas: a unified nosography for focal acral hyperkeratosis, acrokeratoelastoidosis and related disorders. Dermatology 1994;188:2831. Cross Ref link Pubmed link
        • 368  Erkek E, Kocak M, Bozdoğan O, Atasoy P, Birol A. Focal acral hyperkeratosis: a rare cutaneous disorder within the spectrum of Costa acokeratoelastoidosis. Pediatr Dermatol 2004;21:12830. Cross Ref link Pubmed link

        Acquired disorders of elastic tissue deposition

          Linear focal elastosis

          • 369  Burket JM, Zelickson AS, Padilla RS. Linear focal elastosis (elastotic striae). J Am Acad Dermatol 1989;20:6336. Cross Ref link Pubmed link
          • 370  Vogel PS, Cardenas A, Ross EV, et al. Linear focal elastosis. Arch Dermatol 1995;131:8556. Cross Ref link Pubmed link
          • 371  Kanitakis J, Chouvet B, Dupin M, et al. Linear focal elastosis. Eur J Dermatol 1997;7:3002.
          • 372  Péc J, Chromej I. Linear focal elastosis: what's new? J Eur Acad Dermatol Venereol 2004;18:2479. Cross Ref link Pubmed link
          • 373  Moiin A, Hashimoto K. Linear focal elastosis in a young black man: a new presentation. J Am Acad Dermatol 1994;30:8747. Cross Ref link Pubmed link
          • 374  Jang WS, Lee JW, Koo KH, et al. Could a growth spurt cause linear focal elastosis like striae distensae? Ann Dermatol 2012;24:813. Cross Ref link Pubmed link
          • 375  Jeong JS, Lee JY, Kim MK, et al. Linear focal elastosis following striae distensae: further evidence of keloidal repair process in the pathogenesis of linear focal elastosis. Ann Dermatol 2011;23(Suppl. 2):S1413. Cross Ref link Pubmed link
          • 376  Choi SW, Lee JH, Woo HJ, et al. Two cases of linear focal elastosis: different histopathologic findings. Int J Dermatol 2000;39:2079. Cross Ref link Pubmed link
          • 377  Hagari Y, Mihara M, Morimura T, et al. Linear focal elastosis: an ultrastructural study. Arch Dermatol 1991;127:13658. Cross Ref link Pubmed link
          • 378  Hashimoto K. Linear focal elastosis: keloidal repair of striae distensae. J Am Acad Dermatol 1998;39:30913. Cross Ref link Pubmed link
          • 379  Seo JK, Chen JS, Jung SY, et al. A case of linear focal elastosis with a family history. Ann Dermatol 2010;22:20911. Cross Ref link Pubmed link
          • 380  White G. Linear focal elastosis: a degenerative or regenerative process of striae distensae. J Am Acad Dermatol 1992;22:468. Cross Ref link
          • 381  Neve S, Kirtschig G. Elastotic striae associated with striae distensae after application of very potent topical corticosteroids. Clin Exp Dermatol 2006;31:45282. Cross Ref link Pubmed link

          Late‐onset focal dermal elastosis

          • 382  Tajima S, Shimizu K, Izumi T, et al. Late‐onset focal dermal elastosis: clinical and histological features. Br J Dermatol 1995;133:3035. Cross Ref link Pubmed link
          • 383  Limas C. Late onset focal dermal elastosis: a distinct clinicopathologic entity? Am J Dermatopathol 1999;21:3813. Cross Ref link Pubmed link

          Elastofibroma dorsi

          • 384  Nagamine N, Nohara Y, Ito E. Elastofibroma in Okinawa: a clinicopathologic study of 170 cases. Cancer 1982;50:1794805. Cross Ref link Pubmed link
          • 385  Fukuda Y. Histogenesis of the unique elastinophilic fibres of elastofibroma. Hum Pathol 1987;18:4249. Cross Ref link Pubmed link
          • 386  Kapff PD. Elastofibroma of hand. J Bone Joint Surg 1987;69:4689.
          • 387  Govoni E. Elastofibroma: an in vivo model of abnormal elastoneogenesis. Ultrastruct Pathol 1988;12:32739. Cross Ref link Pubmed link
          • 388  Gartmann H, Groth W, Kuhn A. Elastofibroma dorsi. Z Hautkr 1988;63:5258. Pubmed link
          • 389  Yamazaki K. An ultrastructural and immunohistochemical study of elastofibroma: CD34, MEF‐2, pronine 2 (CD33), and factor XIIIa‐positive proliferating fibroblastic stromal cells connected by Cx43‐type gap junctions. Ultrastruct Pathol 2007;31:20919. Cross Ref link Pubmed link
          • 390  Mortman KD, Hochheiser GM, Giblin EM, et al. Elastofibroma dorsi: clinicopathologic review of 6 cases. Ann Thorac Surg 2007;83:18947. Cross Ref link Pubmed link
          • 391  Nagano S, Yokouchi M, Setoyama T, et al. Elastofibroma dorsi: surgical indications and complications of a rare soft tissue tumour. Mol Clin Oncol 2014;2:4214. Pubmed link
          • 392  Karakurt O, Kaplan T, Gunal N, et al. Elastofibroma dorsi management and outcomes: review of 16 cases. Interact Cardiovasc Thorac Surg 2014;18:197201. Cross Ref link Pubmed link

          Elastoderma

          • 393  Kornberg RL, Hendler SS, Oikarinen AI, et al. Elastoderma: disease of elastin accumulation within the skin. N Engl J Med 1985;312:7712. Cross Ref link Pubmed link
          • 394  Yen A, Wen J, Grau M, et al. Elastoderma. J Am Acad Dermatol 1995;33:38992. Cross Ref link Pubmed link
          • 395  de Waal AC, Blocx WA, Seyger MM, et al. Elastoderma: an uncommon cause of acquired hyperextensible skin. Acta Derm Venereol 2012;92:3289. Cross Ref link Pubmed link

          Papular elastorrhexis

          • 396  Bordas X, Ferrandiz C, Ribera M, et al. Papular elastorrhexis: a variety of nevus anelasticus? Arch Dermatol 1987;123:4334. Cross Ref link Pubmed link
          • 397  Sears JK, Seabury Stone M, Argenyi Z. Papular elastorrhexis: a variant of connective tissue nevus. J Am Acad Dermatol 1988;19:40914. Cross Ref link Pubmed link
          • 398  Choonhakarn C, Jirarattanapochai K. Papular elastorrhexis. A distinct variant of connective tissue nevi or an incomplete form of Buschke–Ollendorff syndrome? Clin Exp Dermatol 2002;27:4547. Cross Ref link Pubmed link
          • 399  Choi Y, Jin SY, Lee JH, et al Papular elastorrhexis: a case and differential diagnosis. Ann Dermatol 2011;23(Suppl. 1):S536. Cross Ref link Pubmed link
          • 400  Schorr WF, Opitz JM, Reyes CN. The connective tissue nevus–osteopoikilosis syndrome. Arch Dermatol 1992;106:20814. Cross Ref link
          • 401  Schirren H, Schirren CG, Stolz W, et al. Papular elastorrhexis: a variant of dermatofibrosis lenticularis disseminata (Buschke–Ollendorff syndrome). Dermatology 1994;189:36872. Cross Ref link Pubmed link
          • 402  Ryder HF, Antaya RJ. Nevus anelasticus, papular elastorrhexis and eruptive collagenoma: clinically similar entities with focal absence of elastic fibres in childhood. Pediatr Dermatol 2005;22:1537. Cross Ref link Pubmed link
          • 403  Lee SH, Park SH, Yoon TJ, et al. Papular elastorrhexis improved by intralesional injection of triamcinolone. J Dermatol 2001;28:56971. Cross Ref link Pubmed link

          Fibromatoses and other causes of diffuse fibrosis

            Fibromatoses

              Palmar fascial fibromatosis

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              • 405  Bower M, Nelson M, Gazzard BG. Dupuytren's contracture in patients infected with HIV. BMJ 1990;300:1645. Cross Ref link Pubmed link
              • 406  Evans RA. The aetiology of Dupuytren's disease. Br J Hosp Med 1986;35:1989.
              • 407  Heathcote JG. Fibromatosis and diabetes mellitus. Lancet 1981;i:1420. Cross Ref link
              • 408  Matthews P. Familial Dupuytren's contracture with predominant female expression. Br J Plast Surg 1979;32:1203. Cross Ref link Pubmed link
              • 409  Critchley EM, Vakil SD, Hayward HW, et al. Dupuytren's disease in epilepsy: result of prolonged administration of anticonvulsants. J Neurol Neurosurg Psychiatry 1976;39:49850. Cross Ref link Pubmed link
              • 410  Larkin JG, Frier BM. Limited joint mobility and Dupuytren's contracture in diabetic, hypertensive and normal populations. BMJ 1986;292:1494. Cross Ref link Pubmed link
              • 411  Arafa M, Steingold RF, Noble J, et al. The incidence of Dupuytren's disease in patients with rheumatoid arthritis. J Hand Surg 1984;9B:1656. Cross Ref link
              • 412  Allen PW. The fibromatoses. A clinicopathologic classification based on 140 cases. Am J Surg Pathol 1977;1:25570. Cross Ref link Pubmed link
              • 413  Piérard GE, Lapière CM. Phenytoin dependent fibrosis in polyfibromatosis syndrome. Br J Dermatol 1979;100:33541. Cross Ref link Pubmed link
              • 414  Hassell TM, Page RC, Narayanan AS, et al. Diphenylhydantoin (Dilantin) gingival hyperplasia: drug‐induced abnormality of connective tissue. Proc Natl Acad Sci USA 1976;73:290912. Cross Ref link Pubmed link
              • 415  Kiess W, Butenandt O. Development of Dupuytren's contracture during growth hormone therapy. Lancet 1993;342:1812. Cross Ref link Pubmed link
              • 416  Palmer KT, D'Angelo S, Syddall H, et al. Dupuytren's contracture and occupational exposure to hand‐transmitted vibration. Occup Environ Med 2014;71:2415. Cross Ref link Pubmed link
              • 417  Murrell GAC, Francis MJ, Bromley L, et al. Free radicals and Dupuytren's contracture. BMJ 1987;295:13735. Cross Ref link Pubmed link
              • 418  Granger DN. Superoxide radicals in feline intestinal ischaemia. Gastroenterology 1981;81:229. Pubmed link
              • 419  James WD, Odom RB. The role of the myofibroblast in Dupuytren's contracture. Arch Dermatol 1980;116:80711. Cross Ref link Pubmed link
              • 420  Baird KS, Alwan WH, Crossan JF, Wojciak B. T‐cell mediated response in Dupuytren's disease. Lancet 1993;341:16223. Cross Ref link Pubmed link
              • 421  Gabbiani G, Manjo G. Dupuytren's contracture: fibroblast contraction. An ultrastructural study. Am J Pathol 1972;66:13146. Pubmed link
              • 422  Murrell GA. The role of the fibroblast in Dupuytren's contracture. Hand Clin 1991;7:66980. Pubmed link
              • 423  Bailey AJ, Sims TJ, Gabbiani G, et al. Collagen of Dupuytren's disease. Clin Sci Mol Med 1977;53:499502. Pubmed link
              • 424  Ulrich D, Hrynyschyn K, Pallua N. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in sera and tissue of patients with Dupuytren's disease. Plast Reconstr Surg 2003;112:127986. Cross Ref link Pubmed link
              • 425  Koźna EM, Glowacki A, Olazyk K, et al. Dermatan sulphate remodeling associated with advanced Dupuytren's contracture. Acta Biochim Pol 2007;54:82130. Pubmed link
              • 426  Ling RSM. The genetic factor of Dupuytren's disease. J Bone Joint Surg 1963;45B:70918.
              • 427  Becker K, Tinschert S, Lienert A, et al. The importance of genetic susceptibility in Dupuytren's disease. Clin Genet 2015;87:4837. Cross Ref link Pubmed link
              • 428  Forrester HB, Temple‐Smith B, Ham S, et al. Genome‐wide analysis using exon arrays demonstrates an important role of expression of extracellular matrix, fibrotic control and tissue remodelling genes in Dupuytren's disease. PLOS One 2013;8(3):e59056. Cross Ref link Pubmed link
              • 429  Rodrigo JJ, Niebauer JJ, Brown RL, et al. Treatment of Dupuytren's contracture. Long‐term result after fasciotomy and fascial excision. J Bone Joint Surg Am 1976;58:3807. Pubmed link
              • 430  Shaw DL, Wise D, Holms W. Dupuytren's disease treated by palmar fasciectomy and an open palm technique. J Hand Surg 1996;21B:4845. Cross Ref link
              • 431  Gelman S, Schlenker R, Bachoura A, et al. Minimally invasive partial fasciectomy for Dupuytren's contracture. Hand (NY) 2012;7:3649. Cross Ref link
              • 432  Badalamente MA, Hurst LC, Hentz VR. Collagen as a clinical target. Nonoperative treatment of Dupuytren's disease. J Hand Surg 2002;27A:78898. Cross Ref link
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              • 434  Murrell GAC. Hypothesis for the resolution of Dupuytren's contracture with allopurinol. Spec Sci Technol 1987;10:10712.
              • 435  Hurst LC, Badalamente MA. Nonoperative treatment of Dupuytren's disease. Hand Clin 1999;15:97107. Pubmed link
              • 436  Degreef I, Tejpar S, Sciot R, De Smet L. High‐dosage tamoxifen as neoadjuvant treatment in minimally invasive surgery for Dupuytren's disease in patients with a strong predisposition toward fibrosis: a randomized controlled trial. J Bone Joint Surg Am 2014;96:65562. Cross Ref link Pubmed link
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              Plantar fascial fibromatosis

              • 438  Allen RA, Woolner LB, Ghormley RK, et al. Soft tissue tumours of the sole with special reference to plantar fibromatosis. J Bone Joint Surg Am 1995;37:1426.
              • 439  Warthan TL, Rudolf RI, Gross PR, et al. Isolated plantar fibromatosis. Arch Dermatol 1973;108:8235. Cross Ref link Pubmed link
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              • 443  Motolese A, Mola F, Cherubino M, et al. Squamous cell carcinoma and Ledderhose disease: a case report. Int J Low Extrem Wounds 2013;12:297300. Cross Ref link Pubmed link
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              • 445  Jacob CI, Kumm RC. Benign anteromedial plantar nodules of childhood: a distinct form of plantar fibromatosis. Pediatr Dermatol 2000;17:4724. Cross Ref link Pubmed link
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              Penile fibromatosis

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              • 464  Hsu GC, Chen HS, Hsieh CH, et al. Long term results of autologous venous grafts for penile morphological reconstruction. J Androl 2007;28:18693. Cross Ref link Pubmed link

              Knuckle pads

              • 465  Garrod AE. On an unusual form of nodule upon the joints of the fingers. BMJ 1893;29:15761.
              • 466  Mikkelson OH. Knuckle pads in Dupuytren's disease. Hand 1977;9:301. Cross Ref link Pubmed link
              • 467  Morginson WJ. Discrete keratodermas over the knuckle and finger articulations. Arch Dermatol 1955;71:34953. Cross Ref link
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              • 477  Rushing ME, Sheehan DJ, Davis LS. Video game induced knuckle pads. Pediatr Dermatol 2006;23:4557. Cross Ref link Pubmed link
              • 478  Myeroff CM, Stern PJ. Granuloma annulare mimicking dorsal knuckle pads. J Hand Surg 2011;36A:103941. Cross Ref link
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              Pachydermodactyly

              • 481  Al Hammadi A, Hakim M. Pachydermodactyly: case report and review of the literature. J Cutan Med Surg 2007;11:1857. Cross Ref link Pubmed link
              • 482  Verbov J. Pachydermodactyly: a variant of the true knuckle pad. Arch Dermatol 1975;111:524. Pubmed link
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              • 484  Draluck JC, Kopf AU, Hodak E. Pachydermodactyly: first report in a woman. J Am Acad Dermatol 1992;27:3035. Cross Ref link Pubmed link
              • 485  Bardazzi F, Fanti PA, De Padova MP, et al. Localized pachydermodactyly in a woman. Acta Derm Venereol Suppl (Stockh) 1994;74:1523.
              • 486  Bardazzi F, Neri I, Fanti PA, et al. Pachydermodactyly in two young girls. Pediatr Dermatol 1996;13:28891. Cross Ref link Pubmed link
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              • 494  Tompkins SD, McNutt NS, Shea CR. Distal pachydermodactyly. J Am Acad Dermatol 1998;38:35962. Cross Ref link Pubmed link
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              • 497  Lautenschlager S, Itin PH, Rufli T. Pachydermodactyly: reflecting obsessive‐compulsive behavior? Arch Dermatol 1994;130:387. Cross Ref link Pubmed link
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              White fibrous papulosis of the neck

              • 501  Shimizu H, Nishikawa T, Kimura S. White fibrous papulosis of the neck: a review of 16 cases. Jpn J Dermatol B 1985;95:107784.
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              • 503  Cerio R, Gold S, Wilson‐Jones E. White fibrous papulosis of the neck. Clin Exp Dermatol 1991;16:2245. Cross Ref link Pubmed link
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              • 506  Perrin CH, Castenet J, Lacour J‐P, et al. Papulose blanche du cou. Aspects cliniques de pseudoxanthoma elastique. Ann Dermatol Vénéréol 1996;123:11417.
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              • 509  Siragusa M, Schepis C, Palazzo R, et al. Skin pathology findings in a cohort of 1500 adult and elderly subjects. Int J Dermatol 1999;38:3616. Cross Ref link Pubmed link

              Camptodactyly

              • 510  Engbar WD, Flatt AF. Camptodactyly. An analysis of sixty‐six patients and twenty‐four operations. J Hand Surg 1977;2A:21624. Cross Ref link
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              • 525  Le Bourhis L, Benko S, Girardin SE. Nod1 and Nod2 in innate immunity and human inflammatory disorders. Biochem Soc Trans 2007;35:147984. Cross Ref link Pubmed link
              • 526  Parish JG, Horn DB, Thompson M, et al. Familial streblodactyly with amino‐aciduria. BMJ 1963;ii:124750. Cross Ref link
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              Juvenile fibromatoses

                Infantile myofibromatosis
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                • 534  Martignetti JA, Tian L, Li D, et al. Mutations in PDGFRB cause autosomal‐dominant infantile myofibromatosis. Am J Hum Genet 2013;92:10017. Cross Ref link Pubmed link
                • 535  Cheung YH, Gayden T, Campeau PM, et al. A recurrent PDGFRB mutation causes familial infantile myofibromatosis. Am J Hum Genet 2013;92:9961000. Cross Ref link Pubmed link
                • 536  Lee JW Mutations in PDGFRB and NOTCH3 are the first genetic causes identified for autosomal dominant infantile myofibromatosis. Clin Genet 2013;84:34001.
                • 537  Gatibelza ME, Vazgucz BR, Bereni N, et al. Isolated infantile myofibromatoisis of the upper eyelid: uncommon localization and long‐term results after surgical management. J Pediatr Surg 2012;47:14579. Cross Ref link Pubmed link
                • 538  Kikuehi K, Abe R, Shinkuma S, et al. Spontaneous remission of solitary‐type infantile myofibromatosis. Case Rep Dermatol 2011;3:1815. Cross Ref link Pubmed link
                • 539  Martin JM, Jordá E, Calduch L, et al. Self‐healing generalized infantile myofibromatosis. J Eur Acad Dermatol Venerol 2008;22:2368.
                • 540  Wu SY, McCavit TL, Cederberg K, Galindo RL, Leavey PJ. Chemotherapy for generalised infantile myofibromatosis with visceral involvement. J Pediatr Hematol Oncol 2015;37:4025. Cross Ref link Pubmed link
                Juvenile hyaline fibromatosis
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                • 542  Chitale AR, Murthy AK, Maniar JK, et al. Juvenile hyaline fibromatosis. Ultrastruct Pathol 1987;11:7715. Cross Ref link Pubmed link
                • 543  Ishikawa H, Maeda H, Takamatsu H, et al. Systemic hyalinosis (juvenile hyaline fibromatosis). Ultrastructure of the hyaline with particular reference to the cross‐banded structure. Arch Dermatol Res 1979;265:195206. Cross Ref link Pubmed link
                • 544  Finlay AY, Ferguson SD, Holt PJA, et al. Juvenile hyaline fibromatosis. Br J Dermatol 1983;108:60916. Cross Ref link Pubmed link
                • 545  Denadai R, Bertola DR, Raposo‐Amaral CE. Hyaline fibromatosis syndrome. New unifying term and surgical approach. Indian J Pathol Microbiol 2012;55:262. Cross Ref link Pubmed link
                • 546  Gupta CK, Singhi MK, Baisal M, et al. Juvenile hyaline fibromatosis in siblings. Indian J Dermatol Venereol Leprol 2005;71:11518. Cross Ref link Pubmed link
                • 547  Mayer DA, Silva A. Juvenile hyaline fibromatosis. A histologic and histochemical study. Arch Pathol Lab Med 1988;112:92831. Pubmed link
                • 548  Winik B, Boente M, Asail R. Juvenile hyaline fibromatosis: ultrastructural study. Am J Dermatopathol 1998;20:3728. Cross Ref link
                • 549  Krishnamurthy J, Dalal BS, Sunita Gubanna MV. Juvenile hyaline fibromatosis. Indian J Dermatol 2011;56:7313. Cross Ref link Pubmed link
                • 550  Fong K, Rama Devi AR, Lai‐Cheng JE, et al. Infantile systemic hyalinosis associated with a putative splice‐site mutation in the ANTXR2 gene. Clin Exp Dermatol 2012;37:6358. Cross Ref link Pubmed link
                • 551  Rampoldi L. Different molecular consequences of frameshift mutations in the ANTXR2 gene. Hum Mutat 2013;34(7):v. Cross Ref link Pubmed link
                • 552  Camarasa JG, Moreno A. Juvenile hyaline fibromatosis. J Am Acad Dermatol 1987;16:8813. Cross Ref link Pubmed link
                • 553  Fayad MN, Yacoub A, Salman S, et al. Juvenile hyaline fibromatosis. Two new cases and a review of the literature. Am J Med Genet 1987;26:12331. Cross Ref link Pubmed link
                • 554  Landing BH, Nadorra R. Infantile systemic hyalinosis: report of four cases of a disease, fatal in infancy, apparently different from juvenile systemic hyalinosis. Pediatr Pathol 1986;6:5579. Cross Ref link Pubmed link
                • 555  Remberger K, Krieg J. Fibromatosis hyalinica multiplex (juvenile hyaline fibromatosis). Cancer 1985;56:61424. Cross Ref link Pubmed link
                • 556  Quintal D, Jackson R. Juvenile hyaline fibromatosis. A 15‐year follow up. Arch Dermatol 1985;121:10623. Cross Ref link Pubmed link

                Nephrogenic systemic fibrosis

                • 557  Cowper S, Robin H, Steinberg S, et al. Scleromyxedema‐like cutaneous diseases in renal‐dialysis patients. Lancet 2000;356:10001. Cross Ref link Pubmed link
                • 558  Chopra T, Kandukurti K, Shah S, Ahmed R, Panesar M. Understanding nephrogenic systemic fibrosis. Int J Nephrol 2012; Article ID 912189. Pubmed link
                • 559  Swaminathan S, High WA, Ranville J, et al. Cardiac and vascular metal deposition with high mortality in nephrogenic systemic fibrosis. Kidney Int 2008;73:141318. Cross Ref link Pubmed link
                • 560  Daftari Besheli L, Aran S, Shagdar K, et al. Current status of nephrogenic systemic fibrosis. Clin Radiol 2014;69:6618. Cross Ref link Pubmed link
                • 561  Weller A, Barber JL, Olsen OE. Gadolinium and nephrogenic systemic fibrosis: an update. Pediatr Nephrol 2013;29:192737. Cross Ref link Pubmed link
                • 562  Grobner T. Gadolinium: a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis? Nephrol Dial Transplant 2006;21:11048. Cross Ref link Pubmed link
                • 563  Edward M, Quinn J, Mukherjee S, et al. Gadodiamide contrast agent ‘activates’ fibroblasts: a possible cause for nephrogenic systemic fibrosis. J Pathol 2008;214:58493. Cross Ref link Pubmed link
                • 564  Schmidt‐Lauber C, Bossaller L, Abujudeh HH, et al. Gadolinium‐based compounds induce NLRP3‐dependent IL‐1b production and peritoneal inflammation. Ann Rheum Dis 2014; doi: 10.1136/annrheumdis‐2013‐204900 (epub).
                • 565  Nainani N, Panesar M. Nephrogenic systemic fibrosis. Am J Nephrol 2008;29:19. Cross Ref link Pubmed link
                • 566  Swaminathan S, Ahmed I, McCarthy JT, et al. Nephrogenic fibrosing dermopathy and high‐dose erythropoietin therapy. Ann Intern Med 2006;145:2345. Cross Ref link Pubmed link
                • 567  Naylor E, Hu S, Robinson‐Bostom L. Nephrogenic systemic fibrosis with septal panniculitis mimicking erythema nodosum. J Am Acad Dermatol 2008;58:14950. Cross Ref link Pubmed link
                • 568  Solomon GJ, Wu E, Rosen PP. Nephrogenic systemic fibrosis mimicking inflammatory breast carcinoma. Arch Pathol Lab Med 2007;131:1458. Pubmed link
                • 569  Holtzem KE, Nardone B, Lomasney JW, et al. Superior vena cava obstruction associated with nephrogenic systemic fibrosis. J Drugs Dermatol 2014;13:61518. Pubmed link
                • 570  Bernstein EJ, Isakova T, Sullivan ME, Chibnik LB, Wolf M, Kay J. Nephrogenic systemic fibrosis is associated with hypophosphataemia: a case‐control study. Rheumatology (Oxford) 2014;53:161317. Cross Ref link Pubmed link
                • 571  Streams BN, Liu V, Liegois N, et al. Clinical and pathologic features of nephrogenic fibrosing dermopathy: a report of two cases. J Am Acad Dermatol 2003;48:427. Cross Ref link Pubmed link
                • 572  Kalb RE, Helm TN, Sperry H, et al. Gadolinium‐induced nephrogenic systemic fibrosis in a patient with an acute and transient kidney injury. Br J Dermatol 2007;158:60710. Cross Ref link Pubmed link
                • 573  Linfert DR, Schell JO, Fine DM . Treatment of nephrogenic systemic fibrosis: limited options but hope for the future. Semin Dial 2008;21:1559. Cross Ref link Pubmed link
                • 574  Robinson MR, Routhouska SB, Paspulati RM, et al. Alefacept therapy for nephrogenic systemic fibrosis: a case series. J Drugs Dermatol 2011;10:9224. Pubmed link
                • 575  Poisson JL, Low A, Park YA. The treatment of nephrogenic systemic fibrosis with therapeutic plasma exchange. J Clin Apher 2013;28:31720. Cross Ref link Pubmed link

                Environmental and drug‐induced scleroderma

                • 576  Smith V, Vanthuyne M, Vander Cruysson B, et al. Over‐representation of construction‐related occupations in male patients with systemic sclerosis. Ann Rheum Dis 2008;67:144850. Cross Ref link Pubmed link
                • 577  Ward AM, Udnoon S, Watkins J, et al. Immunological mechanism in the pathogenesis of vinyl chloride disease. BMJ 1976;i:9368. Cross Ref link
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                • 579  Sluis‐Cremer GK, Hessel PA, Nizdo EH, et al. Silica, silicosis and progressive systemic sclerosis. Br J Ind Med 1985;42:83843. Pubmed link
                • 580  Marie I, Gehanno JF, Bubenheim M, et al. Prospective study to evaluate the association between systemic sclerosis and occupational exposure and review of the literature. Autoimmun Rev 2014;13:1516. Cross Ref link Pubmed link
                • 581  Saihan EM, Burton JL, Heaton KW. A new syndrome with pigmentation, scleroderma, gynaecomastia, Raynaud's phenomenon and peripheral neuropathy. Br J Dermatol 1978;99:43740. Cross Ref link Pubmed link
                • 582  Sparrow GP. A connective tissue disease similar to vinyl chloride disease in a patient exposed to perchlorethylene. Clin Exp Dermatol 1977;2:1722. Cross Ref link Pubmed link
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                • 586  Iglesias JL, De Moragas JM. The cutaneous lesions of the Spanish toxic oil syndrome. J Am Acad Dermatol 1983;9:15960. Cross Ref link Pubmed link
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                • 588  Kaufman LD, Seidman RJ, Phillips ME, et al. Cutaneous manifestations of the L‐tryptophan‐associated eosinophilia–myalgia syndrome: a spectrum of sclerodermatous disease. J Am Acad Dermatol 1990;23:10639. Cross Ref link Pubmed link
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                • 590  Varga J, Jimenez SA. Chemical exposure‐induced cutaneous fibrosis. Lessons from ‘experiments of nature’. Arch Dermatol 1994;130:97100. Cross Ref link Pubmed link
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                • 594  Palestine RF, Millas JL, Spigel GT, et al. Skin manifestations of pentazocine abuse. J Am Acad Dermatol 1980;2:4755. Cross Ref link Pubmed link
                • 595  Barthelemy H, Hermier C, Perrot H. Nécrose cutanée avec évolution sclérodermiforme aprés l'injection souscutanée d'heparinate de calcium. Ann Dermatol Vénéréol 1985;112:2457.
                • 596  Brunskill NJ, Berth‐Jones J, Graham‐Brown RAC. Pseudosclerodermatous reaction to phytomenadione injection (Texier's syndrome). Clin Exp Dermatol 1988;13:2768. Cross Ref link Pubmed link
                • 597  Pujol RM, Puig L, Moreno A. Pseudoscleroderma secondary to phytomenadione (vitamin K1) injections. Cutis 1989;43:3658. Pubmed link
                • 598  Morel A, Betlloch I. Morphea‐like reaction from vitamin K1. Int J Dermatol 1995;34:2012. Cross Ref link Pubmed link
                • 599  Bourrat E, Moraillon I, Vignon‐Pennamen MD. Placard sclérodermiforme de la cuisse de l'enfant aprés injection de vitamine K1 à la naissance. Ann Dermatol Vénéréol 1996;123:6348.
                • 600  Bernstein RM, Hall MA, Gostelow BE. Morphoea‐like reaction to D‐penicillamine therapy. Ann Rheum Dis 1981;40:424. Cross Ref link Pubmed link
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                • 602  Stewart FA, Gonino AC, Elewski BE. New side effect of TNF‐alpha inhibitors: morphoea. Skinmed 2013;11:5960. Pubmed link
                • 603  Dospinescu P, Jones GT, Basu N. Environmental risk factors in systemic sclerosis. Curr Opin Rheumatol 2013;25:17983. Cross Ref link Pubmed link
                • 604  Finch WR, Rodnan GP, Buckingham RB, et al. Bleomycin‐induced scleroderma. J Rheumatol 1980;7:6519. Pubmed link
                • 605  Liu S, Herault Y, Pavlovic G, et al. Skin progenitor cells contribute to bleomycin‐induced skin fibrosis. Arthritis Rheum 2014;66:70713. Cross Ref link
                • 606  Sternberg EM, van Woert MH, Young SN, et al. Development of a scleroderma‐like illness during therapy with L‐5‐hydroxytryptophan and carbidopa. N Engl J Med 1980;303:7827. Cross Ref link Pubmed link
                • 607  Hassell TM, Page RC, Narayanan AS, et al. Diphenylhydantoin (Dilantin) gingival hyperplasia: drug‐induced abnormality of connective tissue. Proc Natl Acad Sci USA 1976;73:290912. Cross Ref link Pubmed link
                • 608  Guistiniani S, Robustelli F, Marieni M. Hyperplastic gingivitis during diltiazem therapy. Int J Cardiol 1987;15:2479. Cross Ref link Pubmed link
                • 609  Trunnell TN, Waisman M. Hypertrophic retroauricular folds attributable to diphenylhydantoin. Cutis 1982;30:2079. Pubmed link
                • 610  Ilia R, Goldfarb B, Gueron M. Skin thickening and sensory loss of the feet during diltiazem therapy. Int J Cardiol 1992;35:115. Cross Ref link Pubmed link

                Constricting bands of the extremities

                • 611  Meggitt ST, Harper J, Lacour M, et al. Raised limb bands developing in infancy. Br J Dermatol 2002;147:35963. Cross Ref link Pubmed link
                • 612  Patterson T. Congenital ring constrictions. Br J Plast Surg 1961;69:53269.
                • 613  Dent DM, Fataar S, Rose AG. Ainhum and angiodysplasia. Lancet 1981;ii:3967. Cross Ref link
                • 614  Editorial. Ainhum. Lancet 1975;ii:1920.
                • 615  Browne SG. Ainhum. Int J Dermatol 1976;15:34850. Cross Ref link Pubmed link
                • 616  Cignini P, Giorlandino C, Padula F, et al Epidemiology and risk factors of amniotic band syndrome or ADAM sequence. J Prenat Med 2012;6:5963. Pubmed link
                • 617  Glessner JR. Spontaneous intra‐uterine amputation. J Bone Joint Surg Am 1963;45:3515.
                • 618  Petereka ES, Karon IM. Congenital pseudo‐ainhum of the finger. Arch Dermatol 1964;90:1214. Cross Ref link Pubmed link
                • 619  Raque CJ, Stein KM, Lane JM. Pseudo‐ainhum constricting bands of the extremities. Arch Dermatol 1972;105:4348. Cross Ref link Pubmed link
                • 620  Rushton DI. Amniotic band syndrome. BMJ 1983;286:91920. Cross Ref link Pubmed link
                • 621  Young ID, Lindenbaum RH, Thompson EM, et al. Amniotic bands in connective tissue disorders. Arch Dis Child 1985;60:10613. Cross Ref link Pubmed link
                • 622  Lockwood C, Ghidini A, Romero R, et al. Amniotic band syndrome: reevaluation of its pathogenesis. Am J Obstet Gynecol 1989;160:10303. Cross Ref link Pubmed link
                • 623  Moessinger AC. Amniotic band syndrome associated with amniocentesis. Am J Obstet Gynecol 1981;141:58891. Cross Ref link Pubmed link
                • 624  Latteo SA, Taylor AE, Meggitt SJ. Raised limb bands developing in infancy. Br J Dermatol 2006;154:7912. Pubmed link
                • 625  Bockers M, Benes P, Bork K, et al. Persistent skin ulcers, mutilations and acro‐osteolysis in hereditary sensory and autonomic neuropathy. J Am Acad Dermatol 1989;21:7369. Cross Ref link Pubmed link
                • 626  Almond SL, Curley RK, Feldberg L. Pseudoainhum in chronic psoriasis. Br J Dermatol 2003;149:10646. Cross Ref link Pubmed link
                • 627  Christopher AP, Grattan CEH, Colvan MA. Pseudo‐ainhum and erythropoietic protoporphyria. Br J Dermatol 1988;118:11316. Cross Ref link Pubmed link
                • 628  Schamroth JM. Mutilating keratoderma. Int J Dermatol 1986;25:24951. Cross Ref link Pubmed link
                • 629  Kamalan A. Ainhum trichosporosis Z‐plasty. Dermatologica 1981;162:372. Cross Ref link Pubmed link
                • 630  Hung NN. Congenital constriction ring in children: sine plasty combined with removal of fibrous groove and fasciotomy. J Child Orthop 2012;6:18997. Cross Ref link Pubmed link

                Abnormal fibrotic responses to skin injury

                  Keloids and hypertrophic scars

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                  • 632  Zachariae H. Delayed wound healing and keloid formation following argon laser treatment or dermabrasion during isotretinoin treatment. Br J Dermatol 1988;118:7036. Cross Ref link Pubmed link
                  • 633  Bagatin E, dos Santos Guadanhim LR, Yarak S, et al. Dermabrasion for acne scars during treatment with oral isotretinoin. Dermatol Surg 2010;36:4839. Cross Ref link Pubmed link
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                  • 636  Marneros AG, Norris JEC, Olsen BR, et al. Clinical genetics of familial keloids. Arch Dermatol 2001;137:142934. Cross Ref link Pubmed link
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                  • 638  Moustafa MFH, Abdul Fattah AF. Presumptive evidence of the effect of pregnancy oestrogens on keloid growth. Plast Reconstr Surg 1975;56:4503. Cross Ref link Pubmed link
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                  • 640  Ghatnatti V, Sarma D, Saikia U. Enlarged hands and feet: not always acromegaly. Indian J Endocrinol Metab 2012;16(Suppl. 2):S31820. Cross Ref link Pubmed link
                  • 641  Kelly AP. Keloids: a review. Dermatol Clin 1988;7:1309.
                  • 642  Paradisi M, Angelo C, Conti G, et al. Dubowitz syndrome with keloidal lesions. Clin Exp Dermatol 1994;19:457.
                  • 643  Scott MH Jr, Scott MJ, Scott AM. Linear keloids resulting from abuse of anabolic androgenic steroid drugs. Cutis 1994;53:413. Pubmed link
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                  • 645  Zhang K, Garner W, Cohen L, et al. Increased types I and III collagen and transforming growth factor‐b1 mRNA and protein in hypertrophic burn scar. J Invest Dermatol 1995;104:7504. Cross Ref link Pubmed link
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                  • 647  Sidgwick GP, Bayat A. Extracellular matrix molecules implicated in hypertrophic and keloid scarring. J Eur Acad Dermatol Venereol 2012;26:14152. Cross Ref link Pubmed link
                  • 648  Bailey AJ, Bazin S, Sims TJ, et al. Characterization of the collagen of hypertrophic and normal human scars. Biochim Biophys Acta 1975;405:41221. Cross Ref link Pubmed link
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                  • 650  Hunzelmann N, Anders S, Sollberg S, et al. Coordinate induction of collagen type I and biglycan expression in keloids. Br J Dermatol 1996;135:3949. Cross Ref link Pubmed link
                  • 651  Younai S, Nichter LS, Wellisz T, et al. Modulation of collagen synthesis by transforming growth factor‐b in keloid and hypertrophic scar fibroblasts. Ann Plast Surg 1994;33:14851. Cross Ref link Pubmed link
                  • 652  Haisa M, Okochi H, Grotendorst GR. Elevated levels of PDGF and receptors in keloid fibroblasts contribute to an enhanced response to PGDF. J Invest Dermatol 1994;103:5603. Cross Ref link Pubmed link
                  • 653  Chen JJ, Zhao S, Cen Y, et al. Effect of heat shock protein 47 on collagen accumulation in keloid fibroblast cells. Br J Dermatol 2007;156:118895. Cross Ref link Pubmed link
                  • 654  Crowe N, Parkhouse N, McGrouther D, et al. Neuropeptide‐containing nerves in painful hypertrophic human scar tissue. Br J Dermatol 1994;130:44452. Cross Ref link Pubmed link
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                  • 656  Linares HA, Kischer CW, Dobrkovsky M, et al. The histiotypic organization of the hypertrophic scar in humans. J Invest Dermatol 1972;59:32331. Cross Ref link Pubmed link
                  • 657  Kischer CW, Bunce H III, Shetlar MR. Mast cell analyses in hypertrophic scars, hypertrophic scars treated with pressure and mature scars. J Invest Dermatol 1978;70:3557. Cross Ref link Pubmed link
                  • 658  Meenakshi J, Jayaraman V, Ramakrishnan KM, et al. Ultrastructural differentiation of abnormal scars. Ann Burns Fire Disasters 2005;18:838. Pubmed link
                  • 659  Matsuoka LY, Uitto J, Wortsman J, et al. Ultrastructural characteristics of keloid fibroblasts. Am J Dermatopathol 1988;10:5058. Cross Ref link Pubmed link
                  • 660  Granick M, Kimura M, Kim S, et al. Telomere dynamics in keloid. Eplasty 2011;11:e15. Pubmed link
                  • 661  Bloemen MC, van der Veer VM, Ulrich MM, et al. Prevention and curative management of hypertrophic scar formation. Burns 2009;35:46375. Cross Ref link Pubmed link
                  • 662  Kanaar P, Oort J. Fibrosarcomas developing in scar tissue. Dermatologica 1969;138:31219. Cross Ref link Pubmed link
                  • 663  Ud‐Din S, Bayat A. Strategic management of keloid disease in ethnic skin: a structured approach supported by the emerging literature. Br J Dermatol 2013;169(Suppl. 1):7181. Cross Ref link Pubmed link
                  • 664  Jalali M, Bayat A. Current use of steroids in management of abnormal raised skin scars. Surgeon 2007;5:17580. Cross Ref link Pubmed link
                  • 665  Gauglitz GG, Korting HC, Pavicic T, et al. Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. Mol Med 2011;17:11325. Cross Ref link Pubmed link
                  • 666  Gold MH. A controlled clinical trial of topical silicone gel sheeting in the treatment of hypertrophic scars and keloids. J Am Acad Dermatol 1994;30:5067. Cross Ref link Pubmed link
                  • 667  O'Brien L, Pandit A. Silicone gel sheeting for preventing and treating hypertrophic and keloid scars. Cochrane Database Syst Rev 2006;(1):CD003826. Pubmed link
                  • 668  Wong T‐W, Chiu H‐C, Chen J‐S, et al. Symptomatic keloids in two children: dramatic improvement with silicone cream occlusive dressing. Arch Dermatol 1995;131:7757. Cross Ref link Pubmed link
                  • 669  Kischer CW, Shetlar MR, Shetlar CL. Alteration of hypertrophic scars induced by mechanical pressure. Arch Dermatol 1975;111:604. Cross Ref link Pubmed link
                  • 670  Tzitotzios C, Profyris C, Sterling J. Cutaneous scarring: pathophysiology, molecular mechanisms, and scar reduction therapeutics. Part II. Strategies to reduce scar formation after dermatologic procedures. J Am Acad Dermatol 2012;66:1324. Cross Ref link Pubmed link
                  • 671  Hatamipour E, Mehrabi S, Hatamipour M, et al. Effects of combined intralesional 5‐fluorouracil and topical silicone in prevention of keloids: a double‐blind randomized clinical trial study. Acta Med Iran 2011;49:12730. Pubmed link
                  • 672  Sadeghinia A, Sadeghinia S. Comparison of the efficacy of intralesional triamcinolone acetonide and 5‐fluorouracil tattooing for the treatment of keloids. Dermatol Surg 2012;38:1049. Cross Ref link Pubmed link
                  • 673  España A, Solano T, Quintanilla E. Bleomycin in the treatment of keloids and hypertrophic scars by multiple needle punctures. Dermatol Surg 2001;27:237. Pubmed link
                  • 674  Camacho‐Martinez FM, Rey ER, Serrano FC, et al. Results of a combination of bleomycin and triamcinolone acetonide in the treatment of keloids and hypertrophic scars. An Bras Dermatol 2013;88:38794. Cross Ref link Pubmed link
                  • 675  Bailey JN, Waite AE, Clayton WJ, et al. Application of topical mitomycin C to the base of shave‐removed keloid scars to prevent their recurrence. Br J Dermatol 2007;156:6826. Cross Ref link Pubmed link
                  • 676  Stashower ME. Successful treatment of earlobe keloids with imiquimod after tangential shave excision. Dermatol Surg 2006;32:3806. Pubmed link
                  • 677  Ud‐Din S, Thomas G, Morris J, et al. Photodynamic therapy: an innovative approach to the treatment of keloid disease evaluated using subjective and objective non‐invasive tools. Arch Dermatol Res 2013;305:20514. Cross Ref link Pubmed link
                  • 678  Ahuja RB, Chatterjee P. Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids. Burns 2014;40:5838. Cross Ref link Pubmed link
                  • 679  Mamalis AD, Lev‐Tov H, Nguyen D‐H, et al. Laser and light‐based treatment of keloids: a review. J Eur Acad Dermatol Venereol 2014;28:68999. Cross Ref link Pubmed link
                  • 680  Perry D, Colthurst J, Giddings P, et al. Treatment of symptomatic abnormal skin scars with electrical stimulation. J Wound Care 2010;19:44753. Cross Ref link Pubmed link
                  • 681  Chu Y, Guo F, Li Y, Li X, Zhou T, Guo Y. A novel truncated TGF‐beta receptor II down‐regulates collagen synthesis and TGF‐beta I secretion of keloid fibroblasts. Connect Tissue Res 2008;49:928. Cross Ref link Pubmed link
                  • 682  Lee JH, Kim SE, Lee AY. Effects of interferon‐alpha‐2b on keloid treatment with triamcinolone acetonide intralesional injection. Int J Dermatol 2008;47:1836. Cross Ref link Pubmed link
                  • 683  van Leeuwen MC, Stokmans SC, Bulstra AE. Surgical excision with adjuvant irradiation for treatment of keloid scars: a systematic review. Plas Reconstr Surg Glob Opin 2015;3:e440. Cross Ref link
                  • 684  Jones CD, Guiot L, Samy M, Gorman M, Tehrani H. The use of chemotherapeutics for the treatment of keloid scars. Dermatol Reports 2015;7:5880. Pubmed link

                  Perforating dermatoses

                  • 685  Burgdorf W, Plewig G, Wolff HH, Lamdthaler M, eds. Braun‐Falco's Dermatology, 3rd edn. Berlin: Springer, 2008.
                  • 686  Rapini RP, Herbert AA Drucker CR. Acquired perforating dermatosis. Evidence for combined transepidermal elimination of both collagen and elastic fibers. Arch Dermatol 1989;125:10748. Cross Ref link Pubmed link
                  • 687  Patterson JW. The perforating disorders. J Am Acad Dermatol 1984;10:56181. Cross Ref link Pubmed link
                  • 688  Mehregan RH. Transepithelial elimination. Curr Probl Dermatol 1970;3:12447. Cross Ref link
                  • 689  Patterson JW. Progress in the perforating dermatoses. Arch Dermatol 1989;125:11213. Cross Ref link Pubmed link
                  • 690  Akoglu G, Emre S, Sunqu N, et al. Clinicopathological features of 25 patients with acquired perforating dermatosis. Eur J Dermatol 2013;23:86471. Pubmed link
                  • 691  Zelger B, Hintner H, Aubock J, Fritsch PO. Acquired perforating dermatosis. Arch Dermatol 1991;127:695700. Cross Ref link Pubmed link

                  Acquired perforating dermatosis

                  • 692  Ramirez‐Fort MK, Khan F, Rosendahl CO, et al. Acquired perforating dermatosis: a clinical and dermatoscopic correlation. Derm Online J 2013;19(7):18958.
                  • 693  Patterson JW. The perforating disorders. J Am Acad Dermatol 1984;10:56181. Cross Ref link Pubmed link
                  • 694  Cochran RJ, Tucker SB, Wilkin JK, et al. Reactive perforating collagenosis of diabetes mellitus and renal failure. Cutis 1983;31:558. Pubmed link
                  • 695  Poliak SC, Lebwohl MG, Parris A, et al. Reactive perforating collagenosis associated with diabetes mellitus. N Engl J Med 1982;306:814. Cross Ref link Pubmed link
                  • 696  Rapini RP, Herbert AA, Drucker CR, et al. Acquired perforating dermatosis: evidence of combined transepidermal elimination of both collagen and elastic fibres. Arch Dermatol 1989;125:10748. Cross Ref link Pubmed link
                  • 697  Stone RA. Kyrle‐like lesions in two patients with renal failure undergoing dialysis. J Am Acad Dermatol 1981;5:7079. Cross Ref link Pubmed link
                  • 698  Morton CA, Henderson IS, Jones MC, et al. Acquired perforating dermatosis in a British dialysis population. Br J Dermatol 1996;135:6717. Cross Ref link Pubmed link
                  • 699  Gagnon IAL, Desai T. Dermatological diseases in patients with chronic kidney disease. J Nephropathol 2013;2:1049. Cross Ref link Pubmed link
                  • 700  Patterson JW. Progress in the perforating dermatoses. Arch Dermatol 1989;125:11213. Cross Ref link Pubmed link
                  • 701  Akoglu G, Emre S, Sunqu N, et al. Clinicopathological features of 25 patients with acquired perforating dermatosis. Eur J Dermatol 2013;23:86471. Pubmed link
                  • 702  Kikuchi N, Ohtsuka M, Yamamoto T. Acquired perforating dermatosis: a rare association with dermatomyositis. Acta Derm Venereol 2013;93:7356. Cross Ref link Pubmed link
                  • 703  Piqué‐Dura E, Equia P, Garcia‐Vázquez O. Acquired perforating dermatosis associated with natalizumab. J Am Acad Dermatol 2013;68:e1857. Cross Ref link Pubmed link
                  • 704  Zelger B, Hintner H, Aubock J, Fritsch PO. Acquired perforating dermatosis. Arch Dermatol 1991;127:695700. Cross Ref link Pubmed link
                  • 705  Kim SW, Kim MS, Lee JH, et al. A clinicopathological study of thirty cases of acquired perforating dermatosis in Korea. Ann Dermatol 2014;26:16271. Cross Ref link Pubmed link
                  • 706  Choudhury N, Aggarwal I, Dutta D, Ghosh AGS, Chatterjee G, Chowdhury S. Acquired perforating dermatosis and Addison's disease due to disseminated histoplasmosis: presentation and clinical outcome. Dermatoendocrinology 2013;5:3058. Cross Ref link
                  • 707  Mehregan AH, Schwartz OD. Reactive perforating collagenosis. Arch Dermatol 1967;96:27782. Cross Ref link Pubmed link
                  • 708  Kanan MW. Familial reactive perforating collagenosis and intolerance to cold. Br J Dermatol 1974;91:40514. Cross Ref link Pubmed link
                  • 709  Nair BKH, Sarojini PA, Basheer AM, et al. Reactive perforating collagenosis. Br J Dermatol 1974;91:399403. Cross Ref link Pubmed link
                  • 710  Cerio R, Calnan CD, Wilson‐Jones E. A clinico‐pathological study of reactive perforating collagenosis: report of 10 cases [Abstract]. Br J Dermatol 1987;117(Suppl. 32):1617. Cross Ref link
                  • 711  Fretzin DF, Beal DW, Jao W. Light and ultrastructural study of reactive perforating collagenosis. Arch Dermatol 1980;116:10548. Cross Ref link Pubmed link
                  • 712  Millard PR, Young E, Harrison DE, et al. Reactive perforating collagenosis: light, ultrastructural and immunohistological studies. Histopathology 1986;10:104756. Cross Ref link Pubmed link
                  • 713  Bovenmeyer DA. Reactive perforating collagenosis. Experimental production of the lesion. Arch Dermatol 1970;102:31317. Cross Ref link Pubmed link
                  • 714  Chae KS, Park YM, Cho SH, et al. Reactive perforating collagenosis associated with periampullary carcinoma. Br J Dermatol 1998;139:54850. Cross Ref link Pubmed link
                  • 715  Delacretaz J, Gattlen JM. Verrucous perforating collagenoma. Dermatologica 1976;152:656. Cross Ref link Pubmed link
                  • 716  Laugier P, Woringer F. Reflexions au sujet d'une collagenome perforant verruciforme. Ann Dermatol Syphiligr (Paris) 1963;90:2932.
                  • 717  Moulin G, Balme B, Musso M, Thomas L. Le collagénome perforant verruciforme, une dermatose par inclusion exogène? A propos d'un cas induit par le chlorure de calcium. Ann Dermatol Vénéréol 1995;122:5914.
                  • 718  Knox JM, Knox JM, Dinehart SM, et al. Acquired perforating disease in oil field workers. J Am Acad Dermatol 1986;14:60511. Cross Ref link Pubmed link
                  • 719  Shoenfeld RJ, Grekin JN, Mehregan A. Calcium deposition in the skin. A report of four cases following electroencephalography. Neurology 1965;15:47780. Cross Ref link Pubmed link
                  • 720  Goette DK. Transepidermal elimination of altered collagen after intralesional adrenal steroid injections. Arch Dermatol 1984;120:53940. Cross Ref link Pubmed link
                  • 721  Katz R, Hood AF. Transepidermal elimination following the use of a topical adrenal steroid. Arch Dermatol 1985;121:41213. Cross Ref link Pubmed link
                  • 722  Kruger K, Tebbe B, Krengel S, et al. Acquired reactive perforating dermatosis. Successful treatment with allopurinol in two cases. Hautzart 1999;50:11520. Cross Ref link
                  • 723  Tilz H, Beck JC, Legat F, et al. Allopurinol in the treatment of acquired perforating dermatosis. An Bras Dermatol 2013;88:947. Cross Ref link Pubmed link
                  • 724  Mii S, Yatsa R, Hayashi R, et al. Acquired reactive collagenosis successfully treated with narrow‐band ultraviolet B. Acta Derm Venereol 2009;89:5301. Cross Ref link Pubmed link
                  • 725  Serrano G, Aliaga A, Lorente M, et al. Reactive perforating collagenosis responsive to PUVA. Int J Dermatol 1988;27:11819. Cross Ref link Pubmed link
                  • 726  Sezar R, Erkek E. Acquired perforating dermatosis successfully treated with photodynamic therapy. Photodermatol Photoimmunol Photomed 2012;28:502. Cross Ref link Pubmed link
                  • 727  Yang A, Chong WS, Tay HL. Effective treatment of uraemic pruritus and acquired perforating dermatosis with amitriptyline. Australas J Dermatol 2014;55:e547. Cross Ref link Pubmed link
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                  Elastosis perforans serpiginosa

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                  • 740  Na SY, Choi M, Kim MJ, et al. Penicillamine‐induced elastosis perforans serpiginosa and cutis laxa in a patient with Wilson's disease. Ann Dermatol 2010;22:46871. Cross Ref link Pubmed link
                  • 741  Hashimoto K, Hill WR. Elastosis perforans serpiginosa: histochemical and enzymic digestion studies. J Invest Dermatol 1960;35:714. Cross Ref link Pubmed link
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                  • 745  Khatu SS, Dhurat RS, Nayak CS, et al. Penicillamine‐induced elastosis perforans serpiginosa with abnormal ‘lumpy‐bumpy’ elastic fibers in lesional and non‐lesional skin. Indian J Dermatol Venereol Leprol 2011;77:558. Cross Ref link Pubmed link
                  • 746  Mehregan AH. Elastosis perforans serpiginosa. A review of the literature and report of 11 cases. Arch Dermatol 1968;97:38193. Cross Ref link Pubmed link
                  • 747  Catterall MD, Padley NR. Elastosis perforans serpiginosa. Clin Exp Dermatol 1979;4:11922. Cross Ref link Pubmed link
                  • 748  Schamroth JM. Elastosis perforans serpiginosa in a patient with renal disease. Arch Dermatol 1988;122:824. Cross Ref link
                  • 749  Whyte HJ, Winkelmann RK. Elastosis perforans: the association of congenital anomalies, and salient facts in histology. J Invest Dermatol 1960;35:11322. Cross Ref link Pubmed link
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                  • 751  Ratnavel RC, Norris PG. Penicillamine‐induced elastosis perforans serpiginosa treated successfully with isotretinoin. Dermatology 1994;189:813. Cross Ref link Pubmed link
                  • 752  Langeveld‐Wildschut EG, Toonstra J, et al. Familial elastosis perforans serpiginosa. Arch Dermatol 1993;129:2057. Cross Ref link Pubmed link
                  • 753  Outland JD, Brown TS, Callen JP. Tazarotene is an effective therapy for elastosis perforans serpiginosa. Arch Dermatol 2002;138:16971. Cross Ref link Pubmed link
                  • 754  Kelly SC, Purcell SM. Imiquimod therapy for elastosis perforans serpiginosa. Arch Dermatol 2006;142:82930. Cross Ref link Pubmed link
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                  • 756  Kaufman AJ. Treatment of elastosis perforans serpiginosa with the flashlamp pulsed dye laser. Dermatol Surg 2000;26:10602. Cross Ref link Pubmed link
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                  • 759  Saxena M, Tope WD. Response of elastosis perforans serpiginosa to pulsed CO2, Er:YAG, and dye lasers. Dermatol Surg 2003;29:6778. Pubmed link